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Critical loads - assessment of uncertainty

The effects of data uncertainty in applications of the critical loads concept were investigated on different spatial resolutions in Sweden and northern Czech Republic. Critical loads of acidity (CL) were calculated for Sweden using the biogeochemical model PROFILE. Three methods with different structural complexity were used to estimate the adverse effects of SO2 concentrations in northern Czech R

Protein folding variants, for better or for worse? The lesson learned from HAMLET.

Popular Abstract in Swedish Vad är det för något i human mjölk som dödar cancer celler? Kan “fel” veckade proteiner vara nyttiga? Kan fett vara inblandat i protein veckning? Det är några av frågorna som tas upp i denna avhandling. Allt levande består av proteiner som i sin tur är uppbyggda av amino syror. Det finns 20 st. olika amino syror som på olika sätt kan länkas samman till proteinkedjor. DBy varying its secondary or tertiary structure a single protein can attain new biological functions. The amyloid forming proteins are the best known examples where a change in conformation leads to the formation of amyloid fibrils that accumulate in tissues and cause disease. a-lactalbumin in contrast, is an example of a protein that acquires a beneficial function when the conformation is altered

Importance of the iron–sulfur component and of the siroheme modification in the resting state of sulfite reductase

The active site of sulfite reductase (SiR) consists of an unusual siroheme–Fe4S4 assembly coupled via a cysteinate sulfur, and serves for multi-electron reduction reactions. Clear explanations have not been demonstrated for the reasons behind the choice of siroheme (vs. other types of heme) or for the single-atom coupling to an Fe4S4 center (as opposed to simple adjacency or to coupling via chains

Aeolian activity in Sweden: an unexplored environmental archive

During the course of this three-year project, we have studied aeolian deposits at 70 sites within sixteen areas in south-central Sweden. Inland dunes have been the focus, but some sites with coversand and coastal dunes have also been investigated. We have mapped dune morphology, mainly by LiDAR-based remote sensing, studied the internal sediment architecture by ground-penetrating radar profiling a

Solar variability over the Holocene period : disentangling geomagnetic and solar influences on a new continuous 10Be record from Little Dome C, Antarctica

Reliable information on solar activity over the Holocene period is important to predict the Sun in the future and to understand the mechanism behind the Sun-climate linkage. Presently, there are discrepancies in the proxy data of solar activity due to reasons that are not yet understood. This leads to major uncertainties in Holocene solar reconstructions. This PhD project aims to improve the Holoc

Methane flux measurements with low-cost solid state sensors in Kobbefjord, West Greenland

Vad spelar Arktis för roll i klimatförändringarna? Denna avlägsna, och glest befolkade, del av världen utgör faktiskt en viktig del av klimatsystemet. Arktis spelar en betydande roll i kolets kretslopp; vilket innefattar såväl koldioxid och metan, två av de viktigaste växthusgaserna. Förändringar i koncentrationer av växthusgaser påverkar hur mycket värme som hålls kvar i jordens atmosfär. VåtmarkMethane is one of the most important greenhouse gases, and the Arctic region plays an important role in its dynamics. Due to limited observations in this remote and often harsh environments, large uncertainties surround the role of the Arctic region in a warming climate. In this thesis, I examine the performance of the three low-cost solid state sensors, Figaro sensors TGS2600-B00, TGS2611-C00 an

Nyhetsbrev juni 2012

JUNI 2012 Nyhetsbrev från stiftelsen Forska Lund - Insamlingsstiftelsen för forskning och utbildning inom Lunds universitet Tack för alla bidrag Ett stort tack för alla fantastiska bidrag som vi har fått in till forskningen vid Lunds universitet via stiftelsen Forska Lund. I skrivandets stund är det 80 000 kronor fördelat på 58 gåvor under 2012. Väldigt få kan på egen hand åstadkomma stora skillna

https://www.lu.se/sites/www.lu.se/files/nyhetsbrev_juni_2012.pdf - 2026-05-15

Geophysical Investigation of a Rural Water Point Installation Program in Nampula Province, Mozambique

There are many projects in Mozambique for poverty reduction. One of these projects is funded by Millennium Challenge Account (MCA) and is aimed to install a total of 600 rural water points in the province of Nampula and Cabo Delgado in crystalline rock zone. Each water point consists of a drilled well, a water pump and a communal washing basin. Vertical Electrical Sounding (VES) was used for asse

Extensive central nervous system involvement in Merkel cell carcinoma : a case report and review of the literature

INTRODUCTION: Merkel cell carcinoma is a rare malignant cutaneous neoplasm that is locally invasive and frequently metastasizes to lymph nodes, liver, lungs, bone and brain. The incidence of Merkel cell carcinoma has increased in the past three decades.CASE PRESENTATION: A 65-year-old Caucasian man presented with a sudden onset of severe headache and a three-month history of balance disturbance. M

Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay

Lysosomal membrane permeabilization (LMP) contributes to tissue involution, degenerative diseases, and cancer therapy. Its investigation has, however, been hindered by the lack of sensitive methods. Here, we characterize and validate the detection of galectin puncta at leaky lysosomes as a highly sensitive and easily manageable assay for LMP. LGALS1/galectin-1 and LGALS3/ galectin-3 are best suite

Synthesis of naproxen-imprinted polymer using Pickering emulsion polymerization

For the last decades, molecular imprinting is developing intensively, especially in the case of the application of new imprinting techniques. In this work, for the first time, a Pickering emulsion polymerization was used to synthesize the S-naproxen-imprinted polymer spheres following a noncovalent protocol. To enhance the knowledge about imprinting process using mentioned technique, thorough anal

Poly(arylene piperidinium) hydroxide ion exchange membranes: synthesis, alkaline stability and conductivity

A series of poly(arylene piperidinium)s (PAPipQs) devoid of any alkali-sensitive aryl ether bonds or benzylic sites are prepared and studied as anion exchange membranes (AEMs) for alkaline fuel cells. First, the excellent alkaline stability of the model compound 4,4-diarylpiperidinium is confirmed. Medium molecular weight poly(arylene piperidine)s are then synthesized in polycondensations of N-met

Geophysical investigation of arural water point installation program in Nampula province, Mozambique

There are many projects in Mozambique for poverty reduction. One of these projects is funded by Millennium Challenge Account (MCA) and is aimed to install a total of 600 rural water points in the province of Nampula and Cabo Delgado in crystalline rock zone. Each water point consists of a drilled well, a water pump and a communal washing basin. Vertical Electrical Sounding (VES) was used for asses

Surgical management of cytologically indeterminate thyroid nodules

Nodules in the thyroid are frequent. Preoperative investigations including fine-needle cytology and ultrasound cannot in all patients rule out malignancy. Thus, surgical excision for histopathologic examination is often needed. In this narrative review, we examine aspects of the surgical management of indeterminate thyroid nodules, using a comprehensive review of the available literature. The auth

Pediatric procedural sedation and analgesia in the emergency department : surveying the current European practice

Procedural sedation and analgesia outside the operating theater have become standard care in managing pain and anxiety in children undergoing diagnostic and therapeutic procedures. The objectives of this study are to describe the current pediatric procedural sedation and analgesia practice patterns in European emergency departments, to perform a needs assessment-like analysis, and to identify barr

Antarctic glacial history since the Last Glacial Maximum: an overview of the record on land

This overview examines available circum-Antarctic glacial history archives on land, related to developments after the Last Glacial Maximum (LGM). It considers the glacial-stratigraphic and morphologic records and also biostratigraphical information from moss banks, lake sediments and penguin rookeries, with some reference to relevant glacial marine records. It is concluded that Holocene environmen

Oxidation of 5-hydroxymethylfurfural with a novel aryl alcohol oxidase from Mycobacterium sp. MS1601

Bio-based 5-hydroxymethylfurfural (HMF) serves as an important platform for several chemicals, among which 2,5-furan dicarboxylic acid (FDCA) has attracted considerable interest as a monomer for the production of polyethylene furanoate (PEF), a potential alternative for fossil-based polyethylene terephthalate (PET). This study is based on the HMF oxidizing activity shown by Mycobacterium sp. MS 16

The Ordovician System of South Africa : a review

Outcrops of the Ordovician System in South Africa are extensive; they cover significant portions of the Northern, Western and Eastern Cape provinces as part of the Cape Fold Belt as well as the KwaZulu-Natal Province as supracrustal cover overlying the Natal sector of the Paleoproterozoic Namaqua-Natal metamorphic province. Within the Cape Fold Belt, Ordovician rocks of the Table Mountain Group (P

Choice of Indoor Standard in Hygrothermal Simulations of External Walls – Three Swedish Case Studies

When assessing the moisture damage risks of different external wall designs using hygrothermal simulation software, the user of said software can choose between different inputs for the determination of the indoor climate. This paper aims to compare results from field measurements in three Swedish buildings using different standards available in a widely used commercial hygrothermal simulation sof