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18-F Radiolabelling of Thiodigalactosides as Galectin-3 Inhibitors

Kan man spåra framtida läkemedel i kroppen med radioaktivt fluor? Hur fungerar egentligen olika läkemedel? De allra flesta kanske inte bryr sig, så länge det lindrar din huvudvärk eller tar hand om din infektion. Men när man ska ta fram nya läkemedel måste man tyvärr vara lite mer noggrann än så. Eftersom kostnaden för att gå från en flaska på kemilabbet till en burk på apoteket ofta är miljardbelGalectin-3 is a soluble protein in the body that has been shown involvement in biological processes such as tumour growth and metastasis as well as auto immune disease. Molecules developed by Ulf Nilsson’s research group have shown inhibitory effect in in vitro and in vivo studies towards galecin-3 but to get detailed information about distribution in vivo studies using PET should be performed. Pr

Vad är det värt? - En brottsofferinriktad rättsfallsstudie över straffvärdet för grov kvinnofridskränkning

The crime of gross violation of a woman’s integrity is based on the fact that criminal acts committed by a man against a woman to whom he is, or has been, married or with whom he is, or has been cohabiting under circumstances similar to marriage, are to be assessed more seriously if each of the acts was part of a repeated violation of the person’s integrity and the acts were liable to severely dam

The Immunogenicity and Cytotoxicity of Antibiotic-Derived Mycobacterial Vesicles

Hur kan antibiotikabehandling vid tuberkulos bidra till lungskada? Varför drabbas många tuberkulospatienter av långvariga lungskador, trots att infektionen är botad? Ny forskning visar att antibiotikan i sig kan spela en oväntad roll. När bakterierna utsätts för stressen som antibiotikan orsakar, börjar de släppa ifrån sig små kapslar, liknande mikroskopiska paket, som kan trigga immunförsvaret oTuberculosis (TB) affects millions of people annually and remains one of the leading causes of infectious diseases-related deaths in the world. Current anti-TB treatment consists of a prolonged regimen of multiple antibiotics, which effectively eliminates the bacteria when it is not antibiotic resistant. However, large proportions of the TB-treated individuals experience persistent pulmonary dysfu

Ju fler kockar, desto sämre soppa - Möjligheterna för de ursprungliga ägarna i ett gräsrotsfinansierat aktiebolag att bibehålla kontrollen och inflytandet över bolaget

Avkastningsbaserad gräsrotsfinansiering är en kapitalanskaffningsmetod där små- och nystartade privata aktiebolag via en internetbaserad plattform tar in kapital från många mindre investerare, som i gengäld förvärvar aktier i bolaget. Gräsrotsfinansiering är en effektiv metod, men efter genomförd finansiering är det lilla privata aktiebolaget oftast behäftat med en stor aktieägarkrets, någon som kEquity crowdfunding is when a limited liability company raises capital from a large number of investors whom in return acquire shares in the company. Companies utilize equity crowdfunding to secure funds at an early stage. Equity crowdfunding will however alter the ownership structure of the company to a diversified ownership. In order to maintain its efficiency the company must retain the decisiv

Golare har visst polare En utvecklingsstudie angående möjligheten till eftergift av konkurrensskadeavgift i svensk rätt

Cartels are by nature secretive and thereby hard to find. As a way to stop these hard-core cartels an American system emerged which since has been exported worldwide - a leniency pro-gramme. The affected parties are given an opportunity to inform the authorities and the com-pany who does so is in return released from any potential charges, provided that they follow the authorities guidelines durin

Characterization of circulating T cell-specific exosomes as a possible biomarker in type 1 diabetes

T cell-exosomer som biomarkör vid Typ 1-Diabetes Typ 1-diabetes (T1D) är en autoimmun sjukdom, där kroppens T-celler (immunceller) angriper bukspottskörtelns insulinproducerande betaceller. Insulin är ett viktigt hormon, som reglerar blodsockerhalten i kroppen. Destruktion av betacellerna leder till nedsatt insulinproduktion och därmed höga blodsockerhalter, som följaktligen leder till andra kompType 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, is a growing and serious health problem worldwide with highest incidence in developed countries and among children. It is a T cell-mediated autoimmune disease, characterized by destruction of β-cells of the pancreatic islets of Langerhans, resulting in deficient insulin secretion and hyperglycemia. The cause of the dis

Dealing with unconstitutional changes of government - The African Union Way

Ickekonstitutionella regeringsförändringar har varit ett stort problem i Afrika sen avkoloniseringen och militärkupper har varit en minst lika vanlig form av regeringsbyte som demokratiska val. Afrikanska unionen (AU) har sen den bildades 2001 utvecklat den afrikanska internationella rätten för att kunna hantera dessa situationer. AU:s föregångare Organisationen för afrikansk enighet (OAU) hade inUnconstitutional changes of government has been a major problem in Africa since decolonization with military coups being a more common way of changing government than democratic elections. The African Union (AU) was established in 2001 and has since then provided a significant development of the African law, not the least in the branch of law covering the AU response to unconstitutional changes of

Functional public procurement for innovation, welfare and the environment

Public procurement can be a great driver of innovation and thereby an important instrument of innovation policy. By using functional specifications, the buyer describes the problem to be solved and what needs to be achieved, instead of describing a product as the solution, which is often the case today. Functional public procurement is potentially a powerful innovation policy instrument for two re

https://www.circle.lu.se/functional-public-procurement-innovation-welfare-and-environment - 2026-05-09

What drives the organic private label customer? A study of the influencing variables on the purchase behaviour

Purpose: The purpose of this thesis is to examine, which of those variables suggested by past research – i.e. consumer attitude, store image, perceived price, packaging and perceived quality - have a significant influence on the customer’s purchase behaviour of organic private labels. Methodology: A quantitative study with a deductive approach and a cross-sectional design was chosen to obtain qua

Juristens förhandlingstekniker - Förhandling med japaner

Detta examensarbete behandlar hur en jurist bör förhandla med japaner samt vad en jurist bör tänka på i en förhandlingssituation. Förhandlingen utgör idag en viktig del av juristens arbete - i stort sett all kontakt med andra människor inbegriper någon form av förhandling. I och med en ökad globalisering agerar nu många svenska affärsjurister över hela världen och god kulturkännedom har blivit en

Insurance information for inbound interns and guests at lu

Microsoft Word - Info om försäkringar mm för inkommande praktikanter, gäster.docx Dear intern/guest, Welcome to Lund University Faculty of Medicine! This email contains important information about your insurance at Lund University. Please read it through carefully. Swedish government provides special insurances called ”Insurance for foreign visitors” for incoming interns, guests and staff. You nee

https://www.medicine.lu.se/sites/medicine.lu.se/files/insurance_information_for_inbound_interns_and_guests_at_lu.pdf - 2026-05-11

Styrelseprotokoll20191218

Styrelseprotokoll 2019-12-18 Sida 1 av 4 STYRELSEPROTOKOLL Diarienummer Biologiska institutionen Datum 2019-12-18 Protokoll institutionsstyrelsen Närvaro Närvarande ledamöter Carin Jarl Sunesson, prefekt, ordförande, Marita Cohn, Nils Cronberg, Violeta Kaleskovska, Carina Rasmussen, Karin Rengefors, Johannes Rousk, Tobias Uller, Niklas Wahlberg, Frånvarande ledamöter Anton Andersson-Strand, Marcus

https://www.biologi.lu.se/internt/sites/biologi.lu.se.internt/files/2020-12/styrelseprotokoll20191218.pdf - 2026-05-11

Near real-time mapping of floodwater mosquito breeding sites using aerial photographs

Summary: Floodwater mosquitoes occur in temporary flooded areas and can cause tremendous nuisance in the near and far surroundings. In the Nedre Dalälven region in Central Sweden, mosquito control is based on application of the biological larvicide Bacillus thuringiensis israelensis (BTI) by helicopter. Precise mapping of the floodwater mosquito breeding sites, a prerequisite for successful BTI tr

Oettle ruth

Microsoft Word - Thesis of Ruth Oettle The Environment for sale? The examination of the critical features of a third‐party in facilitating a transaction in the market for environmental offsets. Ruth Oettle ruth.oettle@gmail.com 25 May 2008 Submitted in partial fulfilment of the requirements for the International Master’s Programme in Environmental Studies and Sustainability Science (LUMES), Lund U

https://www.lumes.lu.se/sites/lumes.lu.se/files/oettle_ruth.pdf - 2026-05-11

Quantifying archaeo-organic degradation – A multiproxy approach to understand the accelerated deterioration of the ancient organic cultural heritage at the Swedish Mesolithic site Ageröd

Despite a growing body of evidence concerning accelerated organic degradation at archaeological sites, there have been few follow-up investigations to examine the status of the remaining archaeological materials in the ground. To address the question of archaeo-organic preservation, we revisited the Swedish, Mesolithic key-site Ageröd and could show that the bone material had been subjected to an

Molecular studies of pancreatic cancer: Characterization of the transforming growth factor beta signaling pathway

Popular Abstract in Swedish Pankreascancer (cancer i bukspottkörteln) drabbar ungefär 900 personer om året i Sverige. Tumörformen har tidigare varit vanligare hos män men är numera lika vanlig hos män och kvinnor. Pankreascancer är ovanligt före 40 års ålder, men ökar stadigt med åldern och ungefär 80% av dem som drabbas är över 60 år gamla. Pankreascancer är en aggressiv tumörform och på grund avIn the present thesis, genetic abnormalities in pancreatic cancer were studied, with special emphasis on alterations of components involved in the transforming growth factor beta (TGFB) signaling pathway. In the first study, fluorescence in situ hybridization and cytogenetic analyses revealed aberrations of chromosome 18 in all 13 pancreatic carcinoma cell lines studied, in particular frequent bre

Data Science Lab

Data Science Lab is part of Data Science Hub. The lab contains financial data terminals and is located on the first floor in LUSEM Learning Hub, room B:307, Alfa 5. It is open around the clock to all students at LUSEM. Data Science Lab and Financial databases In the lab you have access to financial data terminals. It is open for all students at LUSEM.Where: Room B:307, LUSEM Learning Hub, Alfa 5.

https://www.lusem.lu.se/organisation/lund-university-school-economics-and-management-library/lusem-library/data-science-lab - 2026-05-09

Process-based models not always better than empirical models for predicting budburst of Norway spruce and birch in Europe.

Budburst models have mainly been developed to capture the processes of individual trees, and vary in their complexity and plant physiological realism. We evaluated how well eleven models capture the variation in budburst of birch and Norway spruce in Germany, Austria, the United Kingdom and Finland. The comparison was based on the models performance in relation to their underlying physiological as

”Jag hoppas någon gång kunna berätta för mina patienter att vi har ett botemedel” – Vetenskap och Hä

”Jag hoppas någon gång kunna berätta för mina patienter att vi har ett botemedel” – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök ”Jag hoppas någon gång kunna berätta för mina patienter att vi har ett botemedel” 2022-04-28 Veckans Wallenbergforskare, barnkardiologen Karin Tran Lundmark, be

https://www.vetenskaphalsa.se/jag-hoppas-nagon-gang-kunna-beratta-for-mina-patienter-att-vi-har-ett-botemedel/ - 2026-05-09