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Chronic glomerular and tubular nephrotoxicity has been reported in up to 50% and 25%, respectively, of children and adolescents treated with ifosfamide and up to 60% and 30% of those given cisplatin. Up to 35% of children have proteinuria and microalbuminuria, implying chronic glomerular damage, after unilateral nephrectomy for a renal tumour. We are still learning about nephrotoxicity due to the

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Innovation literature shows that the characteristics of a company's innovation processes determine their performance in different areas. In this study, we adopt a general conceptual model from innovation theory and apply it to packaging innovation. This helps identify and describe subprocesses in packaging innovation and how to measure their performance. It also links the packaging innovation proc

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Pseudopotentials, tight-binding models, and k p theory have stood for many years as the standard techniques for computing electronic states in crystalline solids. Here, we present the first new method in decades, which we call atomistic k . p theory. In its usual formulation, k . p theory has the advantage of depending on parameters that are directly related to experimentally measured quantities,

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Classifying active galactic nuclei (AGNs) is a challenge, especially for BL Lacertae objects (BLLs), which are identified by their weak emission line spectra. To address the problem of classification, we use data from the fourth Fermi Catalog, Data Release 3. Missing data hinder the use of machine learning to classify AGNs. A previous paper found that Multivariate Imputation by Chain Equations (MI

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Introduction: Induction of labor (IOL) is one of the most common obstetrical procedures, with an increasing rate. The prostaglandin E1 analogue misoprostol is frequently used as a primary method of labor induction. The optimal dose and route of administration is yet to be ascertained. Aim: To compare efficiacy and safety between a regimen of sublingually administered misoprostol and a regimen of o

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In developing EnergyNet we have leveraged and are extending lessons from telecom's shift from a centralized, circuit-switched phone system to decentralized, packet-switched data networks. EnergyNet utilizes 1) an Energy Router that enforces galvanic separation and utilizes software-controlled energy flows over a DC backplane, 2) Energy Local and Wide Area Networks (ELAN/EWAN) based on DC microgrid

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Contamination or damage to X-ray optics is becoming increasingly problematic for beamlines at 3rd and 4th generation storage-rings and FEL sources. Carbon contamination, induced by ultra-intense photon-beams, can cause a major loss in flux, focusing power, and specific absorptions which are detrimental to spectroscopy. For new light sources, with higher coherence, intensity, and repetition rates,

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BACKGROUND: A child with avoidant/restrictive food intake disorder (ARFID) has a diet so limited that it leads to medical, nutritional, and/or psychosocial problems. ARFID affects both children and their families, often causing parents to feel anxious and isolated. This study aimed to explore the experiences of Swedish parents raising a child with ARFID.METHOD: Data were generated through semi-str

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Hållbarhet och hållbar mobilitet har blivit viktiga mål i national politik och policy. Cykling har dock inte kunnat dra nytta av detta. Om man betraktar cyklingens betydelse under de senaste decennierna, och dess förväntade betydelse i framtiden, finns emellertid få anledningar till optimism, åtminstone inte på nationell och övergripande nivå; cykeln befinner sig fortfarande i skuggan av bilen. DeSustainability and sustainable mobility have become important political goals and have left their mark as important discourses in national policies and programs. Against expectations, cycling has barely benefited from this. Looking back over the shoulder at the significance of cycling over the last few decades and looking forward to suggested implications in the future give no reason for joy, at l

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INTRODUCTION: The gerontological literature suggests that external housing-related control beliefs (HCB) influence activities of daily living (ADL) among older people, but knowledge is scarce for people with Parkinson's disease (PD). This longitudinal study aimed to explore the directions of the relationship between external HCB and ADL among people with PD.METHODS: Baseline (T1) and 3-year follow

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Money is central to capitalism and to our many sustainability crises. Could we remake money so as to advance sustainable economies and fair societies? A growing number of scholars, politicians, and activists think we can, and they are doing it from the bottom up. This book examines how grassroots groups, municipalities and radical crypto-entrepreneurs are remaking money by designing and organising

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Eritreans are currently forcefully conscripted into national service, which is indefinite and requires them to engage in tasks that are beyond a ‘purely military character’. These include economic development activities, work for private companies and even domestic work for their superiors, for which they receive little or no pay. Deserting or evading national service is heavily punished and refug

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Humanitarian Visas Key to Improving Europe’s Migration Crisis RAOUL WALLENBERG’S HUMANITARIAN VISAS The best known Humanitarian Visa is the so called Schutz Pass issued by Swedish diplomat Raoul Wallenberg. He served at the Budapest legation in the critical end phase of the Nazi reign in Hungary. In collaboration with staff at the embassy and the Swedish foreign ministry, and with the support of t

https://rwi.lu.se/app/uploads/2016/04/Humanitarian-Visas-policy-brief.pdf - 2026-07-17

Publication in embo mol med

REST suppression mediates neural conversion of adult human fibroblasts via microRNA‐dependent and ‐independent pathways Research Article REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways Janelle Drouin-Ouellet1,†, Shong Lau1,†, Per Ludvik Brattås1, Daniella Rylander Ottosson1, Karolina Pircs1, Daniela A Grassi1, Lucy M Collins2,

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_embo_mol_med.pdf - 2026-07-17

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Uppsatsen studerar gällande rätt i Sverige rörande omvändelseförsök med utgångspunkt i en statlig utredning (SOU 2023:37) som gjordes förra året. Utredningen drog slutsatsen att en särskild reglering av omvändelseförsök inte behöver införas i Sverige och uppsatsen redogör för argumenten som fördes. Då området förblir oreglerat undersöker uppsatsen vilka konstitutionella rättigheter som kan tänkas This essay studies the legal framework in Sweden regarding so-called “conversion therapies” with the starting point in a Swedish Government Official Report (SOU 2023:37) that was published last year. The government report suggested that there is no need to regulate so-called “conversion therapies” or, as more commonly called, SOGIECE in Sweden. The essay presents and discusses the argument made by

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I Sverige idag uppskattas det att 16 procent konsumerar alkohol på ett sätt som bedöms som riskbruk. Detta är något som kan ge upphov till en rad olika konsekvenser, såsom sjukdomar, skador och missbruk. Vidare visar studier att fyra procent av individer mellan 16-24 år lider av någon form av spelproblem. Precis som med alkohol kan det vid konsumtion av spel utvecklas ett missbruk. Det är konstate

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Popular Abstract in Swedish Transplantation av lungor är ett relativt nytt behandlingsalternativ vid svår lung-sjukdom. Den första lungtransplantationen på människa gjordes 1963. Patienten dog efter 18 dagar i njursvikt. Mellan 1963 och 1980 gjordes ca 40 lungtransplantationer i världen med nedslående resultat. Medianöverlevnaden var enbart 8,5 dagar och den patient som levde längst levde bara 6 mDuring the past 15 years lung transplantation has been established as a therapeutic option for patients with end-stage pulmonary disease. The results have improved over time and some transplantation centers now show 1-year survival rates above 80%. The number of donors has remained relatively constant during later years but the demand is increasing resulting in longer waiting times and an increasi

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Popular Abstract in Swedish Ser man bakåt i historien har människan alltid försökt reparera eller ersätta vävnader i kroppen vid skador. En av de äldsta rapporterna om användande av biomaterial är runt 4000 år gammalt. I detta fall användes linnefibrer som suturmaterial. Från början användes naturliga material som collagen, silke, hår, bomull och olika cellulosamaterial. Under senare hälften av 19The aim of the this thesis was surface modification of a biomedical polyurethane (PUR), Pellethane 2363-80AE*, to improve the biocompatibility. Surfaces modified by poly(ethylene oxide) (PEO) were prepared either by grafting PEO covalently at the PUR surface by a two-step reaction, or by using amphiphilic polymers containing PEO as the hydrophilic part. The amphiphilic polymers consisted of one co