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Evidence for an involvement of striatal D1 receptors in levodopa-induced dyskinesia has been presented whereas the contribution of striatal D2 receptors remains controversial. In addition, whether D1 and D2 receptors located in the substantia nigra reticulata shape the response to levodopa remains unknown. We therefore used dual probe microdialysis to unravel the impact of striatal and nigral D1 o
Objective. Costimulatory receptor CD226 plays an important role in T cell activation, differentiation, and cytotoxicity. This study was undertaken to investigate the genetic association of CD226 with susceptibility to systemic lupus erythematosus (SLE) and to assess the functional implications of this association. Methods. Twelve tag single-nucleotide polymorphisms (SNPs) in CD226 were typed in 1,
Cycling as mode of transport can be seen as a sustainable and active mode of travel that can be part of the solution for climate change and urban congestion. Many cities in Europe are now investing in cycling to reduce their carbon emissions and make their spaces more liveable and accessible. Some cities have arguably already achieved an advanced cycling culture where cycling is normalised and wov
The doctrine of abuse of rights in a general sense is not a new one. According to some scholars it can be traced back to as early as Roman law and statements by Praetor Cicéro regarding the purchase of property. The influence of Roman law can be seen in many Member States today and the theory of abuse of law has lived on in many states such as France. However, the doctrine of abuse in EU law is a
This study explores how members of Myanmar’s largest political parties perceive inclusion of its citizen in the democratic process. Through a threefold aim the study has looked at how party members’ understanding of inclusion is externalised within the parties; whether these perceptions implies hindrances to Myanmar’s democratic development; and how the analytical findings can contribute to the th
Syftet med denna uppsats är att visa hur staden Lagos har vuxit i storlek och ökat i befolkning mellan åren 1990-2008. Jämförelser över staden för åren 1990, 1999 och 2008 har gjorts så att huvudragen i stadens tillväxt har kunnat visas och analyseras. Baserat på hur staden har vuxit och förändrats under dessa år så har även tre stycken framtidsmodeller för hur Lagos kan tänkas se ut år 2020 produThe aim of this thesis is to show how the city of Lagos has grown in size and population between the years 1990-2008. Comparisons over the city for the years 1990, 1999 and 2008 have been made so that the main characteristics of the city’s growth can be shown and analyzed. Based on this expansion future prospects for the city has been provided through producing three different scenarios on how Lag
This paper examines the benefits of using CBT-techniques as a therapeutic tool within the treatment of stuttering. Stuttering is a complex disorder that involves not only speech disfluencies but also psychological and interpersonal problems as a consequence of the interaction of thoughts, emotions and behaviour. This case study describes CBT carried out with a young woman with stuttering difficult
Examensarbetets titel: Positionering och dess betydelse för framgång inom mobilbranschen Seminariedatum: 2010-06-04 Ämne/kurs: FEK P01, examensarbete, magisternivå, Strategic Management, 15 högskolepoäng Författare: André Agnesson Franzén och Jesper Ling Handledare: Matts Kärreman Fem nyckelord: Positionering, mobilbranschen, Sony Ericsson, interna faktorer, externa faktorer Syfte: Syftet med denn
The aim of this thesis is to demonstrate how the concept of the ideal victim of crime contributes to re-victimize significant populations exploited by human traffickers. The argument is that seeing women trafficked in the sex industry as the norm together with a focus only on “women and children” as victims/survivors contribute to further hide-and therefore re-victimize-men and young boys. The Peo
This thesis aims to explore the role a private network of investors can play when addressing and investing in the Sustainable Development Goals. The network explored is the Sida facilitated network Swedish Investors for Sustainable Development. The network was created in 2016 and has since worked to increase the knowledge among the members regarding how they should invest more efficiently in the S
Idag behandlas cancer med bl.a. strålbehandling, tyvärr ger denna många gånger biverkningar. Detta beror på att strålningen inte bara skadar cancerceller utan även friska celler, eftersom strålningen måste passera frisk vävnad för att nå in till cancertumören. Det har nyligen utvecklats en ny strålbehandlingsteknik som kan minska strålningen till frisk vävnad samtidigt som tumören ges en hög strål"Intensity modulated radiation therapy (IMRT) is a fairly new modality in the treatment of cancer with radiotherapy. The original idea is Swedish and has existed for more than 20 years. But it is only in recent years that clinics have implemented the IMRT technique. IMRT uses many segments (small subfields) that build up radiation fields with nonuniform energy fluence. With this technique, be
Syftet med examensarbetet har varit att åstadkomma en kapacitetsökning i Thom Lightings lager i Landskrona. Målet var att bestämma hur en lämplig lagerlayout med ett smalgångsalternativ skulle se ut och hur mycket kapacitetsökning denna lösning skulle åstadkomma. Ytterligare en målsättning var att se över vilka rutiner som krävs för att skapa ett effektivt lager och slutligen göra en simulering so
BACKGROUND: The majority of out-of-hospital cardiac arrests (OHCAs) occur at place residence, which is associated with worse outcomes in unselected prehospital populations. Our aim was to investigate whether location of arrest was associated with outcome in a selected group of initial survivors admitted to intensive care.METHODS: This is a post-hoc analysis of the Targeted Temperature Management a
A search for dark matter produced in association with a Higgs boson decaying to b-quarks is performed using pp collisions at a centre-of-mass energy of √s=13 TeV. The dataset has an integrated luminosity of 79.8 fb−1 and was recorded with the ATLAS detector at the Large Hadron Collider. Selected collision events comprise large missing transverse momentum and either two b-tagged small radius jets o
En större mängd kvartsavslag och brända ben, upptäckta vid rekognosering (Norrbottens Museum) av hyggesberedda ytor norr om byn Sammakko, c. 40 km SO Gällivare, har tolkats att indikera ett kortvarigt använt boplatsområde. Platsen, liggande c. 100 meter norr Linaälven och i kanten av en nästan igenväxt göl, genomgick arkeologisk förundersökning sommaren 2019. Insamlat material av brända ben ochA large number of quartz fragments from knapping andburnt bone, discovered during reconnaissance (NorrbottensMuseum) of forest-cleared areas north of the villageSammakko, c. 40 km SE of Gällivare, have been interpretedto indicate a short-term used dwelling site. Th esite, located c. 100 meters north of the Linaälven Riverand at the edge of an almost overgrown pond, underwentarchaeological prelimin
BackgroundObservational data suggests that an anterior or apical left ventricular (LV) position in Cardiac Resynchronization Therapy (CRT) is associated with worse outcome and higher likelihood of “non-response”. It is not known whether the benefits of optimizing LV lead position in a second procedure outweighs the procedural risks.ObjectiveTo evaluate the clinical effects of LV lead repositioning
The purpose of this study was to investigate the effects of experimental data on performance of a developed Bayesian algorithm tailored for orphan source search, estimating which parameters affect the accuracy of the algorithm. The algorithm can estimate the position and activity of a gamma-ray point source from experimental mobile gamma spectrometry data. Bayesian estimates were made for source p
Observables sensitive to the anomalous production of events containing hadronic jets and missing momentum in the plane transverse to the proton beams at the Large Hadron Collider are presented. The observables are defined as a ratio of cross sections, for events containing jets and large missing transverse momentum to events containing jets and a pair of charged leptons from the decay of a Z/ γ∗bo
Pilot-scale tests were run with ozonation for reduction of 24 pharmaceuticals at 10 full-scale wastewater treatment plants in southern Sweden. Reduction was evaluated based on doses of 3, 5 and 7 g O3/m3 at all plants. The reduction of pharmaceuticals reached on average 65% at 3 g O3/m3, 78% at 5 g O3/m3 and 88% for 7 g O3/m3 in terms of total concentration of pharmaceuticals. Specific ozone dose Pilot-scale tests were run with ozonation for reduction of 24 pharmaceuticals at 10 full-scale wastewater treatment plants in southern Sweden. Reduction was evaluated based on doses of 3, 5 and 7 g O3/m3 at all plants. The reduction of pharmaceuticals reached on average 65% at 3 g O3/m3, 78% at 5 g O3/m3 and 88% for 7 g O3/m3 in terms of total concentration of pharmaceuticals. Specific ozone dose
