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This thesis discusses institutional sustainability and transitions to sustainable development. These concepts are explored through a qualitative case study on rural groundwater management institutions in Aweil East, South Sudan. The primary question guiding the discussion is how a transition towards sustainable development is reflected in this particular case. The secondary questions supporting th
For over a decade the healthcare industry has attempted to mimic the non-medical industry with the use of incident reporting as one of many tools used to increase patient safety. But often healthcare workers are trained to perfect individual performance and the incident reporting descriptions are frequently weighted with character flaws (Leape, 1997). Human error is viewed as a personal failure in
Hur resonerar elever och lärare på musikestetiska programmet kring respons i musikundervisningen? Syftet med denna studie är att öka kunskapen om respons i musikundervisningen på estetiska programmet samt få en inblick i hur elever hittar motivation efter respons från sina lärare. Uppsatsen bygger på en kvalitativ undersökning som är formad efter intervjuer med elever och lärare på estetiska progrWhat are the thoughts and opinions of teachers and students at the arts programme regarding response in music teaching? The purpose of this study is to increase awareness about response in music education in the arts programme in Swedish upper secondary school, and to gain insight into how students find motivation after receiving response from their teachers. This essay is based on a qualitative s
Watersheds are patchy landscapes, hard to understand and deal with. Previous scholarship investigated various institutional arrangements to tackle classical problems related to the overuse, misuse and mismanagement of water resources. While studies eloquently identified conditions under which individuals cooperate and avoid a “tragedy of the commons” scenario, they hardly scrutinized the role of p
Polarized light is a key feature of the blue sky, used by many animals as a sensory cue for compass navigation. Like other insects, locusts perceive the E-vector orientation of polarized light with a specialized region of their compound eye, the dorsal rim area. Neurons in the brain relay this information through several processing stages to the central complex. The central complex has a modular n
Corynebacterium glutamicum is a rod-shaped actinomycete with a distinct model of peptidoglycan synthesis during cell elongation, which takes place at the cell poles and is sustained by the essential protein DivIVA(CG) (C. glutamicum DivIVA). This protein contains a short conserved N-terminal domain and two coiled-coil regions: CC1 and CC2. Domain deletions and chimeric versions of DivIVA were used
Alterations in the scaffold protein WRAP53β have previously been linked to carcinogenesis and, in particular, associated with an increased risk for epithelial ovarian cancer. Here, we investigated the pathogenic impact and prognostic significance of WRAP53β in connection with epithelial ovarian cancer and examined the underlying mechanisms. We find that reduced expression of WRAP53β in ovarian tum
Bile-tolerant Helicobacter species such as Helicobacter pullorum, Helicobacter bilis, and Helicobacter hepaticus are associated with hepatic disorders in animals and may be involved in the pathogenesis of chronic liver diseases (CLD) in humans. Antibody responses to cell surface proteins of H. pullorum, H. bilis, and H. hepaticus in serum samples from patients with CLD, a randomized population gro
The TINEL Project is running a series of camps for staff at higher education institution to support them in developing inclusive eLearning. The first camp was conducted face-to-face, but the coronavirus pandemic meant that the second camp was conducted online. This created a case study in inclusive eLearning in itself and allowed us to experience and reflect on the challenges and opportunities of
Brazil's Atlantic Forest biome is one of the world's biodiversity hotspots, whose heterogeneous ecosystems are threatened by habitat loss and climate change. Palaeoecological research can provide essential context for the impacts of anthropogenic climate change in the 21st Century and beyond, but existing studies have notable limitations in the insights they can provide: vegetation proxy data are
The barrier function of the skin is mainly assured by its outermost layer, stratum corneum (SC), which consists of dead keratin-filled cells embedded in a lipid matrix. The skin is daily exposed to an environment with changing conditions in terms of hydration and different chemicals. Here we investigate how a molecule that has reasonable solubility in both hydrophobic and hydrophilic environments
Acute dyspnea with underlying congestion is a leading cause of emergency department (ED) visits with high rates of hospitalization. Adrenomedullin is a vasoactive neuropeptide hormone secreted by the endothelium that mediates vasodilation and maintains vascular integrity. Plasma levels of biologically active adrenomedullin (bio-ADM) predict septic shock and vasopressor need in critically ill patie
Background Patch test reactivity to nickel varies over time. To what extent this variation is associated with fluctuations in the T-cell reactivity to nickel is not known. Objectives Our aim was to investigate the relationship between variation over time in the patch test and the systemic T-cell reactivity to nickel. Methods Patients (n = 15) with a history of contact allergy to nickel were subjec
An important role for WNT-5A is implicated in a variety of tumors, including breast carcinoma. We previously showed that WNT-5A signaling inhibits migration and metastasis of breast cancer cells, and that patients with primary breast cancer in which WNT-5A was expressed have a better prognosis. Despite the fact that RhoGTPase Cdc42 is commonly associated with increased cell migration, we here show
The main aim of the present study was to examine the economic consequences of a reduction in the incidence of clinical mastitis (CM) at herd level under current Swedish farming conditions. A second objective was to ask whether the estimated cost of CM alters depending upon whether the model reflects the fact that in different stages of lactation, CM gives rise to different yield-loss patterns or p
Apart from the relevant lipid-lowering effects, statins have demonstrated significant, although heterogeneous, anti-tumor activities in preventing breast cancer (BC) progression. To characterize the critical pathways behind the diverse responses to therapy, we investigated statin-induced changes in regulation of lipid metabolism and abundance of neutral lipid-containing cytoplasmic lipid droplets
We present an estimate for the convergence rate of the Dirichlet-Neumann iteration for the discretized unsteady transmission problem. Specifically, we consider the coupling of two heat equations on two identical squared domains. The Laplacian is discretized by second order central finite differences and the implicit Euler method is used for the time discretization. For the semidiscrete case, Hensh
