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Dissecting the properties of circulating IgG against streptococcal pathogens through a combined systems antigenomics-serology workflow

This study showcases an integrative mass spectrometry-based strategy combining systems antigenomics and systems serology to characterize human antibodies in clinical samples. This strategy involves using antibodies circulating in plasma to affinity-enrich antigenic proteins in biochemically fractionated pools of bacterial proteins, followed by their identification and quantification using mass spe

Asymptotic Performance Analysis of Distributed Non-Bayesian Quickest Change Detection with Energy Harvesting Sensors

This paper focuses on the distributed non-Bayesian quickest change detection based on the Cumulative Sum (CUSUM) algorithm in an energy harvesting wireless sensor network (WSN), where the distributions before and after the change point are assumed to be known. Each sensor is powered by randomly available harvested energy from the surroundings. It samples the observation signal and computes the log

High Affinity Antibodies to Plasmodium falciparum Merozoite Antigens Are Associated with Protection from Malaria

Background: Malaria kills almost 1 million people every year, but the mechanisms behind protective immunity against the disease are still largely unknown. Methodology/Principal Findings: In this study, surface plasmon resonance technology was used to evaluate the affinity (measured as kd) of naturally acquired antibodies to the Plasmodium falciparum antigens MSP2 and AMA1. Antibodies in serum samp

Proteolysis of purified IgGs by human and bacterial enzymes in vitro and the detection of specific proteolytic fragments of endogenous IgG in rheumatoid synovial fluid

A comparative in vitro survey of physiologically relevant human and microbial proteinases defined a number of enzymes that induced specific hinge domain cleavage in human IgG1. Several of these proteinases have been associated with tumor growth, inflammation, and infection. A majority of the identified proteinases converted IgG to F(ab')(2), and a consistent feature of their action was a transient

Intercomparison of C-14 Analysis of Carbonaceous Aerosols: Exercise 2009

Radiocarbon analysis of the carbonaceous aerosol allows an apportionment of fossil and non-fossil sources of airborne particulate matter (PM). A chemical separation of total carbon (TC) into its subfractions organic carbon (OC) and elemental carbon (EC) refines this powerful technique, as OC and EC originate from different sources and undergo different processes in the atmosphere. Although C-14 an

A Heterobimetallic FeIIIMnII Complex of an Unsymmetrical Dinucleating Ligand: A Structural and Functional Model Complex for the Active Site of Purple Acid Phosphatase of Sweet Potato

The heterodinuclear mixed-valence complex [FeMn(ICIMP)(OAc)(2)Cl] (1) {H2ICIMP = 2-(N-carboxylmethyl)-[N-(N-methylimidazolyl-2-methyl)aminomethyl]-[6-(N-isopropylmethyl)-[N-(N-methylimidazolyl-2-methyl)]aminomethyl-4-methylphenol], an unsymmetrical N4O2 donor ligand} has been synthesized and fully characterized by several spectroscopic techniques as well as by X-ray crystallography. The crystal st

Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro

Certain monoclonal antibodies (mAbs) to type II collagen (CII) induce arthritis in vivo after passive transfer and have adverse effects on chondrocyte cultures and inhibit self assembly of collagen fibrils in vitro. We have examined whether such mAbs have detrimental effects on pre-existing cartilage. Bovine cartilage explants were cultured over 21 days in the presence of two arthritogenic mAbs to

Can Foreign Aid Spur Growth? Empirical evidence from the developing world between 1978 and 2013

This study aims to investigate the impact of foreign aid on economic growth by using an exogenous instrument identified by Galiani et al. (2015). Researchers have through the years failed to agree on whether aid causes growth, being unable to identify an exogenous instrument that can eliminate the endogeneity problem associated with aid and growth. Galiani et al. (2015) claim to have found such an

Automatic Landing without GPS

Sagem Défense et Sécurité (now Safran Electronics & Defense), a French space and defense company of the SAFRAN group, is working on the next generation of Unmanned Aerial System (UAS). This UAS features a fully automatic Unmanned Aerial Vehicle (UAV) equipped with a state-of-the-art navigation system. This navigation system relies mainly on a high-accuracy Inertial Measurement Unit (IMU) coupl

Changing the game - The effects of a radical logo rebranding strategy on the consumer-brand relationship in football

Purpose: The purpose of this thesis is to provide an understanding of how consumer-brand relationships are affected by a radical rebranding strategy of a football club’s logo. This further leads the paper to contribute to the literature of consumer-brand relationships in the special context of football. Methodology: The interpretative nature of this research calls for a qualitative research appro

Disputationer 2022

Anders SjögrenStraffrättsliga förhållningsregler – En rättsvetenskaplig studie av förbuds-, påbuds- och permissivregler som riktar sig till enskildaDatum för disputation: fredagen den 14 oktoberFakultetsopponent: professor em Dan Frände, Helsingfors universitetÄmne: straffrättAbstractThis thesis focuses on conduct rules in criminal law. Such rules prohibit, proscribe and permit different courses o

https://www.jur.lu.se/forskning/disputationer/disputationer-2022 - 2026-05-21

A scattering study of concentrated lens protein solutions and mixtures - Towards understanding the molecular origin of presbyopia

Healthy eye lenses are transparent and flexible, able to adapt shape in order to focus on far away and close-by objects. With age, however, this flexibility is lost, leading to a condition known as presbyopia. This vision disorder where close-by objects appear blurred commonly starts around the age of 40. The aim of this thesis is to elucidate the molecular origin of the gradual hardening of the c

Årsstämmoprotokoll LU Holding 2024 Signerat

Protokoll fört vid årsstämma i LU Holding AB, org.nr 556500-1467, den 24 juni 2024 i Lund Närvarande aktieägare Antal aktier Antal röster Lunds universitet genom Erik Renström 100 __________ 100 __________ Summa 100 100 Dessutom var Kristina Eneroth och Christine Widstrand närvarande. § 1 Ordförande Stämman öppnades av Erik Renström som valdes till ordförande vid stämman. Noterades att ordföranden

https://www.innovation.lu.se/sites/innovation.lu.se/files/2024-08/A%CC%8Arssta%CC%88mmoprotokoll%20LU%20Holding%202024%20signerat.pdf - 2026-05-22

Lintang Hizbullah - Ph.D. Candidate

My bachelor’s degree is in: Inorganic Chemistry from Padjadjaran University, Indonesia I graduated year: 2014 My master’s degree is in: Inorganic Chemistry from Lund University, Sweden I graduated year: 2021 I am a Ph.D. student in Prof. Ebbe Nordlander's group, part of the Chemical Physics Division at Lund University. Here I work on the development of antimalarial drugs where I enhance organometa

https://www.kemi.lu.se/lintang-hizbullah-phd-candidate - 2026-05-21