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High Affinity Antibodies to Plasmodium falciparum Merozoite Antigens Are Associated with Protection from Malaria

Background: Malaria kills almost 1 million people every year, but the mechanisms behind protective immunity against the disease are still largely unknown. Methodology/Principal Findings: In this study, surface plasmon resonance technology was used to evaluate the affinity (measured as kd) of naturally acquired antibodies to the Plasmodium falciparum antigens MSP2 and AMA1. Antibodies in serum samp

Proteolysis of purified IgGs by human and bacterial enzymes in vitro and the detection of specific proteolytic fragments of endogenous IgG in rheumatoid synovial fluid

A comparative in vitro survey of physiologically relevant human and microbial proteinases defined a number of enzymes that induced specific hinge domain cleavage in human IgG1. Several of these proteinases have been associated with tumor growth, inflammation, and infection. A majority of the identified proteinases converted IgG to F(ab')(2), and a consistent feature of their action was a transient

Intercomparison of C-14 Analysis of Carbonaceous Aerosols: Exercise 2009

Radiocarbon analysis of the carbonaceous aerosol allows an apportionment of fossil and non-fossil sources of airborne particulate matter (PM). A chemical separation of total carbon (TC) into its subfractions organic carbon (OC) and elemental carbon (EC) refines this powerful technique, as OC and EC originate from different sources and undergo different processes in the atmosphere. Although C-14 an

A Heterobimetallic FeIIIMnII Complex of an Unsymmetrical Dinucleating Ligand: A Structural and Functional Model Complex for the Active Site of Purple Acid Phosphatase of Sweet Potato

The heterodinuclear mixed-valence complex [FeMn(ICIMP)(OAc)(2)Cl] (1) {H2ICIMP = 2-(N-carboxylmethyl)-[N-(N-methylimidazolyl-2-methyl)aminomethyl]-[6-(N-isopropylmethyl)-[N-(N-methylimidazolyl-2-methyl)]aminomethyl-4-methylphenol], an unsymmetrical N4O2 donor ligand} has been synthesized and fully characterized by several spectroscopic techniques as well as by X-ray crystallography. The crystal st

Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro

Certain monoclonal antibodies (mAbs) to type II collagen (CII) induce arthritis in vivo after passive transfer and have adverse effects on chondrocyte cultures and inhibit self assembly of collagen fibrils in vitro. We have examined whether such mAbs have detrimental effects on pre-existing cartilage. Bovine cartilage explants were cultured over 21 days in the presence of two arthritogenic mAbs to

Highly efficient CO2 and propylene oxide co-polymerization using Zn glutarate/Zn-Cr double metal cyanide composite catalyst

A highly active zinc glutarate-double metal cyanide (DMC) composite catalyst (ZnGA/Zn-CrDMC) was designed for the carbon dioxide (CO2) and propylene oxide (PO) copolymerization reaction. The composite catalyst was synthesized in a rheological phase reaction and characterized using Fourier transform infrared spectroscopy (FT-IR), powder X-ray diffraction (PXRD), and scanning electron microscopy (SE

Dissecting the properties of circulating IgG against streptococcal pathogens through a combined systems antigenomics-serology workflow

This study showcases an integrative mass spectrometry-based strategy combining systems antigenomics and systems serology to characterize human antibodies in clinical samples. This strategy involves using antibodies circulating in plasma to affinity-enrich antigenic proteins in biochemically fractionated pools of bacterial proteins, followed by their identification and quantification using mass spe

Ageing, social participation, and everyday mobility : Facilitating age-friendly environments

Due to the increasing share of older people worldwide, the United Nations has directed an initiative towards a "decade of healthy ageing" to promote "age-friendly environments". This study aims to gain a deeper understanding of how to promote social participation and everyday mobility in later life. The ambition is to increase the knowledge about how to create more age-friendly environments and so

Sylvain Richoz

Universitetslektor Kontaktinformation E-post: sylvain [dot] richoz [at] mgeo [dot] lu [dot] seOrganisation Miljö- och geovetenskapliga institutionen (MGeo) Hämtställe: 16 WebbplatsSylvain Richoz profil i Lunds universitets forskningsportalAndra roller Universitetslektor Geologiska institutionenMy research is focused on:1) the interactions between climate-induced change in seawater chemistry and pa

https://www.geologi.lu.se/sylvain-richoz - 2026-05-17

Shopping Centres, Cycling Accessibility and Planning–The Case of Nova Lund in Sweden

This paper evaluates the history and cycling accessibility of Nova, a shopping centre established in Lund, Sweden, in 2002. The current situation was also analysed through observation and a literature review. Moreover, the study conducted a closer analysis of the history and role of the municipality based on further literature study and interviews with officials. The conclusion of the analysis indThis paper evaluates the history and cycling accessibility of Nova, a shopping centre established in Lund, Sweden, in 2002. The current situation was also analysed through observation and a literature review. Moreover, the study conducted a closer analysis of the history and role of the municipality based on further literature study and interviews with officials. The conclusion of the analysis ind

Kampen om jord: om institutioner, rationella val och viljan att göra rätt i landreformens Zimbabwe

Land Reform in Zimbabwe was instigated at the end of the 1970’s as an effort to ease tensions and more equitably distribute wealth and power between the disenfranchised black population and their white colonial rulers. In this thesis I examine Zimbabwean land reform from a new institutional perspective. More specifically, I examine which of the two institutional logics, logic of appropriateness an

Reconstructing institutional stability and change Conceptualizing the social ontology of institutional stability and change in Historical Institutionalism

Questions about institutional stability and change are critically important for any understanding of political institutions. The field of Historical institutionalism in political science has described, studied and theorized institutions for decades. One of the most recurring concepts utilized in the explanation of institutional stability is path dependence, describing theoretical and empirical mec

SPAC merger vs traditional IPO

Special Purpose Acquisition Companies are surging in popularity as a way for companies to go public. As half of the initial public offerings on US stock exchanges were SPACs in 2021 there seems to be no indication of SPACs slowing down. This thesis examines the performance of companies that went public via a business combination with a SPAC in the year 2020 compared to companies that decided to ta

Navigating the Moral Landscape of Foster Care: : The Risk of Blame and Suspicion in Paid Parenthood

Foster care provides a family‐like upbringing for children who cannot stay with their biological parents for various reasons. While the practice of paying foster parents is not questioned, the level of the fee and how it is spent (or not spent) are morally charged matters. Foster parents’ motives may be questioned by the media, neighbors, or social workers, who may suspect financial gain. Although

Ny teknik - gamla kläder: Motiv till andrahandskonsumtion av kläder via internet

Uppsatsen behandlar delvis internets betydelse för andrahandsmarknaden av kläder men framförallt vilka motiv konsumenterna har när de handlar begagnade kläder via internet. Teorin som används är Pierre Bourdieus teori om smak, fält, habitus och olika former av kapital. Metod för insamling av data bestod av kvantitativ metod i form av webbaserad enkät. Resultatet analyserades sedan i statistiskanal