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A Monosaccharide Residue Is Sufficient to Maintain Mouse and Human IgG Subclass Activity and Directs IgG Effector Functions to Cellular Fc Receptors.

Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly

A role for PKC-epsilon in Fc gamma R-mediated phagocytosis by RAW 264.7 cells

Protein kinase C (PKC) plays a prominent role in immune signaling, and the paradigms for isoform selective signaling are beginning to be elucidated. Real-time microscopy was combined with molecular and biochemical approaches to demonstrate a role for PKC-epsilon in Fcgamma receptor (FcgammaR)-dependent phagocytosis. RAW 264.7 macrophages were transfected with GFP-conjugated PKC isoforms, and GFP m

Recombinant factor IX Fc for the treatment of hemophilia B

Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E

Hur är en socialarbetare?

In this paper I have investigated the construction of the professional social worker in Swedish journals and newspapers. My empiric material is a collection of major articles published in Sweden between 2002 and 2012. The thirteen articles analyzed in this paper is a selection from 1250 relevant articles found between these years. When analyzing the empirical material I have been working with a di

LU Holding Årsredovisning 2020

LU Holding AB 556500-1467 Box 117, SE - 221 00 Lund, Sweden, Visiting address The Spark, Medicon village, Scheeletorget 1, Lund Telephone +46 46-222 00 00 Internet www.innovation.lu.se 1 AÅ rsredovisning för LU Holding AB 556500-1467 Räkenskapsåret 2020-01-01 – 2020-12-31 Transaktion 09222115557446406774 Signerat BA, JA, SF, BN, HP, CW, CE, UR, ST, LW, ME LU Holding AB 556500-1467 Box 117, SE -

https://www.innovation.lu.se/sites/innovation.lu.se/files/2021-08/LU%20Holding%20a%CC%8Arsredovisning%202020.pdf - 2026-05-11

Sensorless method of detecting plunger position in solenoid actuators

This thesis investigates if it is possible to measure the plunger position in a Ledex 282352-023 solenoid actuator without the use of external sensors. To do this, various different methods, all based on comparing the current response to the applied voltage were evaluated from different categories such as calculation time, reliability and distinct position levels. The method that performed best in

Family caregivers of persons with dementia. Experiences of burden, satisfaction and psychosocial intervention.

Popular Abstract in Swedish När en familjemedlem drabbas av en demenssjukdom påverkas även de övriga familjemedlemmarna på något sätt. Allt mer vård och omsorg flyttar in i hemmen och de närståendes roll och funktion blir mycket centrala. Syftet med denna doktorsavhandling var att undersöka hur närstående till demenssjuka personer mår, och att planera, genomföra och undersöka effekten av en 5-vec

Ny teknik för att hitta och behandla prostatacancer – Vetenskap och Hälsa

Ny teknik för att hitta och behandla prostatacancer – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Ny teknik för att hitta och behandla prostatacancer 2017-01-18 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Forskare vid Lunds universitet har tillsammans

https://www.vetenskaphalsa.se/ny-teknik-for-att-hitta-och-behandla-prostatacancer/ - 2026-05-10

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Nyhetsbrev från Akademikerföreningen Sveriges Ingenjörer vid Siemens Energy AB Kontakt: asi.se@siemens-energy.com Redaktörer: SvE, MP, SJ Nr: 06/24 2024-09-12 GRIP to Mercer, G2M Mercer är vårt nya system för att klassificera samtliga befattningar för tjänstemän på företaget. Mercer ersätter vårt tidgare system, GRIP, och efter den 12 september har alla tjänstemän en ny befattningskod synlig i Coi

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/siemens-energy-ab/nyhetsbrev/asi-nyhetsbrev-0624.pdf - 2026-05-10

The search for safe haven assets in the time of a global pandemic

The global pandemic has initially negatively influenced the financial markets all over the world. As a consequence, the volatility in the stock markets increased and investors have experienced great monetary losses. In addition, the volatility spillover has increased between different markets and assets, which additionally amplifies the negative influence by the pandemic. This motivates the search