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Hormone-sensitive lipase (HSL) is expressed and enzymatically active in beta-cells and has been proposed to be involved in the generation of the lipid-derived signal that seems to be necessary for glucose-stimulated insulin secretion. In this study, we investigated whether the expression of HSL in INS-1 cells and in rat islets is affected by exposure to high glucose concentrations. Incubation of I
BACKGROUND: As cardiovascular disease (CVD) is one of the most common causes of mortality worldwide, much interest has been focused on reliable methods to predict cardiovascular risk. DESIGN: A cross-sectional, population-based screening study with 17-year follow-up in Southern Sweden. METHODS: We compared a non-laboratory, consultation-based risk assessment method comprising age, sex, present smo
The oncogene cyclin D1 is highly expressed in many breast cancers and, despite its proliferation-activating properties, it has been linked to a less malignant phenotype. To clarify this observation, we focused on two key components of malignant behavior, migration and proliferation, and observed that quiescent G0/G1 cells display an increased migratory capacity compared to cycling cells. We also f
Here we report an EPR signal that is induced by a pH jump to alkaline pH in the S3 state of the oxygen-evolving complex in photosystem II. The S3 state is first formed with two flashes at pH 6. Thereafter, the pH is changed in the dark prior to freezing of the sample. The EPR signal is 90-100 G wide and centered around g = 2. The signal is reversibly induced with a pK = 8.5 ± 0.3 and is very stabl
The signal crayfish Pacifastacus leniusculus is an invasive species in Sweden, threatening the red-listed nobel crayfish Astacus astacus through spreading the crayfish plague. Time-to-event models can handle censored data on such introduced populations for which the state (successful or not) is only partially known at the last observation, but even though data on introduced populations most often
To assess muscle strength in the knee extensors, knee flexors and ankle dorsiflexors in persons with late effects of polio, and determine how much muscle strength, gender, age and BMI are related to gait performance.
The article examines the formal process of ‘ethical clearance’ for social science research at a large university and illuminates how it functions to undermine its stated purpose. We find that rather than promoting ethical standards, the bureaucratic process creates negative and cynical attitudes and game playing. For almost all participants, the entire procedure is counterproductive and experience
Purpose Visual interpretation of brain amyloid-β (Aβ) PET can be difficult in individuals with borderline Aβ burden. Coregistration with individual MRI is recommended in these cases, which, however, is not always available. This study evaluated coregistration with the early perfusion frames acquired immediately after tracer injection to support the visual interpretation of the late Aβ-frames in PE
Purpose This research aims to deepen the view of willingness to share knowledge within the organization by using the lens of organization-based self-esteem in a case study. Methodology Utilizing an interpretive tradition, especially symbolic interactionism, this research employs a qualitative case study methodology with an abductive approach. The empirical material is gathered through 14 semi-
Drastic emission-reductions are needed to avoid the disastrous consequences of climate change. Flying is one of the highest individual carbon-impact actions. By 2050, the aviation industry’s share on global greenhouse gas emissions is expected to rise by 300 to 700%. An intervention to counteract this development is to reduce flying at universities as they have a critical role in leading sustainab
Originating in the Treaty of Rome, the Common Agricultural Policy (CAP) is the European Union’s largest and first supranational policy, well-known for its high cost, trade distorting effects and its reluctance to change. Despite being subject to three major reform attempts during 1992-2003 many of the original defects still remain. The aim of this thesis is to examine how far reaching the CAP refo
This chapter challenges the widely held belief that more consumer choices lead to better outcomes. This chapter explores how the proliferation of options, while seemingly empowering, can actually lead to decision paralysis, dissatisfaction and unsustainable consumption patterns. The myth is rooted in classical economic theories that equate more choice with freedom and personal satisfaction, but ps
Bildguide för Drupal Rekommendationer Janni Lundqvist Vedam Användarstöd & suppport Webbavdelningen, sektionen Kommunikation 2025 Allmänna tips Använd liggande bilde Ha inte förstora bilde Försök att använda originalbilden och dens forma Alla bilder passar inte överall Bör bild finnas på sidan? Tänk på att storlekarna är endast rekommendationer för de element/funktioner som finns i Drupal
https://www.webbpublicering.lu.se/sites/webbpublicering.lu.se/files/2025-03/BILDGUIDE%201.0.pdf - 2026-07-10
Drones have been used by the military since mid-1970 but the development of autonomous systems from the turn of the millennium and onward has opened the area of UAV to civil service and the public immensely. Today UAV technology saves lives in Search And Rescue operations, complements and supports full scale vehicles at the Police force and assists in surveys and documentation of ground and forest
NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska som vänder sig till fakultetskommunikatörer vid Lunds universitet för vidarespridning i fakultets- och institutionskanaler – Nr 31 v 40 - 2020. UNIVERSITETSGEMENSAMT Universitetet satsar på specialteam för att förebygga sexuella trakasserier efter Tellus-rapport* Vid ett webbinarium den 28 september presenterades resultaten från under
https://www.cec.lu.se/sites/cec.lu.se/files/2020-10/LU-gemensamt%20Mejlutskick%20Nr%2031-2020-v40.pdf - 2026-07-10
Delivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy. Peptide linkage to mAbs has previously been achieved through genetic fusion, chemical conjugation, nano-engineered platforms and high affinity peptides. In this study, we h
