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Din sökning på "M 1707 s 1" gav 18472 sökträffar

Two-step mechanism of inhibition of cathepsin B by cystatin C, due to the inhibitor displacing the occluding loop of the enzyme

Stopped-flow kinetics showed that the inhibition of the lysosomal cysteine proteinase, cathepsin B, by its endogenous inhibitor, cystatin C, occurs by a two-step mechanism, in which an initial, weak interaction is followed by a conformational change. The initial interaction most likely involves binding of the N-terminal region of the inhibitor to the proteinase. Considerable evidence indicates tha

Microstructure analysis of novel resorbable calcium phosphate/sulphate bone cements

This paper presents a new method to obtain porosity in apatitic cements, by mixing a-tricalcium phosphate (alpha-TCP) with calcium sulphate hemihydrate. The material was characterized by X-ray diffraction and observations in Electron Microscopy. The results show that crystals of calcium sulphate stayed embedded in the hydroxyapatite formed from a-TCP. By dissolution of these crystals porosity coul

Blood redistribution in the fetal brain during chronic hypoxia

Background Studies on blood flow velocity in the fetal middle cerebral artery have revealed signs of brain sparing in chronic hypoxia. These signs of brain sparing can disappear in the terminal case, but whether this applies to the whole brain or only parts of it is unknown. Methods Velocity waveforms of the middle cerebral, anterior cerebral and posterior cerebral arteries were recorded in 221 pr

Distribution and functional significance of phosphodiesterase isoenzymes in the human lower urinary tract

To date, it is widely accepted that several disorders of the male and female urogenital tract, such as erectile dysfunction, bladder overactivity, urinary stone disease and the benign prostatic syndrome, can be therapeutically approached by influencing the function of the smooth musculature of the respective organs. In order to achieve a pronounced drug effect without significant adverse events, e

Cognition- and anxiety-related behavior, synaptophysin and MAP2 immunoreactivity in the adult rat treated with a single course of antenatal betamethasone

We investigated the effects of a single course of antenatal betamethasone on cognition- and anxiety-related behavior and synaptophysin and microtubule-associated protein 2 (MAP2) immunoreactivity in the adult rat hippocampus. On d 20 of gestation, pregnant rats were injected with either 1) 170 mu g/kg body weight of betamethasone ("clinically equivalent dose," equivalent to 12 mg twice, 24 h apart

Bronchoscopy and bronchoalveolar lavage findings in cross-country skiers with and without "ski asthma"

Bronchial hyperresponsiveness to methacholine with asthma-like symptoms ("ski asthma") is frequent in elite cross-country skiers. To further the understanding of "ski asthma", 10 nonasthmatic, nonatopic controls and 30 adolescent elite skiers were investigated by bronchoscopy and bronchoalveolar lavage (BAL). Nine skiers were atopic without allergy symptoms. Compared with controls, the macroscopic

Pollen productivity estimates for the reconstruction of past vegetation cover in the cultural landscape of southern Sweden

Pollen productivity estimates (PPE) are one of the critical parameters for a quantitative reconstruction of past vegetation from fossil pollen records. Modern pollen and vegetation data were collected in traditional landscapes of southern Sweden to derive PPE for the most characteristic plant taxa. The 42 selected sites are assumed to be good analogues of historical to prehistorical grasslands. A

Matrilin-2, a large, oligomeric matrix protein, is expressed by a great variety of cells and forms fibrillar networks

Matrilin-2 is a member of the protein superfamily with von Willebrand factor type A-like modules. Mouse matrilin-2 cDNA fragments were expressed in 293-EBNA cells, and the protein was purified, characterized, and used to immunize rabbits. The affinity-purified antiserum detects matrilin-2 in dense and loose connective tissue structures, subepithelial connective tissue of the skin and digestive tra

The effectiveness of enzymatic replacement therapy measured by turbidimetry and the lipaemic index in exocrine pancreatic insufficient young, growing pigs, fed a high-fat diet.

Purpose: Conventionally, the management of exocrine pancreatic insufficiency (EPI) involves the consumption of a specific diet as well as the replacement of pancreatic enzymes, the effectiveness of which is usually measured by a classical method of blood analyses of non-esterified fatty acids (NEFA) and triglycerides (TG). Dietary supplementation with a pancreatic enzyme preparation (PEP), in conj

Optimizing factor prophylaxis for the haemophilia population: where do we stand?

The hallmark of severe haemophilia, defined as a circulating level of factor (F) VIII (haemophilia A cases) or FIX (haemophilia B cases) of < 1%, is recurrent bleeding into muscles and joints (haemarthroses) from an early age of life. The inevitable result of such bleeding is progressive joint damage, leading to disabling arthritis that is typically evident within the first 2 decades of life in pe

The importance of cofactors in the histologic progression of minimal and mild chronic hepatitis C

A follow-up liver biopsy was done 9-16 years (mean 12 years) after initial biopsy in 20 untreated Swedish patients infected with hepatitis C (8 men, 12 women; mean age 30 years at initial biopsy) in whom first biopsy had been classified as chronic persistent hepatitis. A significant progression of liver damage was found when using Histology Activity Index (HAI) scoring according to Knodell (p=0.00

Measurement of D*(+/-) meson production and F-2(c) in deep-inelastic scattering at HERA

The inclusive production of D*+/-(2010) mesons in deep-inelastic scattering is studied with the HI detector at HERA. In the kinematic region 1 < Q(2) < 100 GeV2 and 0.05 < y < 0.7 an e(+) p cross section for inclusive D*+/- meson production of 8.50 +/- 0.42(stat.)(-100)(+1.21)(syst.) nb is measured in the visible range p(tD*) > 1.5 GeV and eta(D*) < 1.5. Single and double differential inclusive D*

Lundatrackitimplementeringsplan

1 Trackit Implementeringsplan - för nya gemensamma rutiner för att följa Lundastudenter före, under och efter studierna vid Lunds universitet November 2012 Styrgruppen för Trackit projektet 2 Implementeringsplan (Trackit) för nya gemensamma rutiner för att följa Lundastudenter före, under och efter studierna vid Lunds universitet Introduktion Trackit! Lundaprojektet har genom en kartläggning av ru

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/lundatrackitimplementeringsplan.pdf - 2026-05-27

Verkstader-for-eget-arbete-940924

Föreskrifter för användande av verkstäder vid Lunds universitet för eget arbete Föreskrifter för användande av verkstäder vid Lunds universitet för eget arbete Beslut av förvaltningschefen 1994-09-02; dnr I A 32 11892/94 Föreskrifter för angiven verksamhet fastställs enligt bilaga. Föreskrifterna gäller fr o m beslutsdatum. Detta beslut har fattats av undertecknad förvaltningschef efter föredragni

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/verkstader-for-eget-arbete-940924.pdf - 2026-05-27

Infoblad Master Markvård 2022

Markvård MASTER I MILJÖVETENSKAP MED NATURVETENSKAPLIG INRIKTNING, 60/120 HP | LUNDS UNIVERSITET MARK- GRUNDEN FÖR LIVSVIKTIGA ORGANISMER! Biotopförstöring och påverkan på växter och djur till följd av ovarsam hantering av skadliga ämnen är vanligt förekommande problem, och sjukdomar orsakade av förorenat dricksvatten är en realitet för miljontals människor. I vårt närområde nås vi allt oftare av

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2022-03/Infoblad%20master%20markv%C3%A5rd%202022.pdf - 2026-05-27

Förankringskapacitet i cementsnåla småhusgrunder

Byggindustrin står inför nya utmaningar i form av skärpta krav när det gäller dess klimatpåverkan. En betydande faktor för byggindustrins klimatpåverkan är den cement som används i betong, eftersom det i samband med tillverkning av cement frigörs stora mängder koldioxid. Platta på mark är en vanlig typ av grundläggning i byggnader i mindre skala, såsom småhus. En typisk småhusplatta av betong ha