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The presence of different time scales in a dynamic model significantly hampers the efficiency of its simulation. In multibody systems the fact is particularly relevant, as the mentioned time scales may be very different, due for example to the coexistence of mechanical components controlled by electronic drive units, and may also appear in conjunction with significant nonlinearities. This paper pr
Alzheimer's Disease (AD) is the most prevalent form of dementia worldwide, yet the development of therapeutics has been hampered by the absence of suitable biomarkers to diagnose the disease in its early stages prior to the formation of amyloid plaques and the occurrence of irreversible neuronal damage. Since oligomeric A beta species have been implicated in the pathophysiology of AD, we reasoned
Objectives: We evaluated a method for gas monitoring in the mastoid cavity using tunable diode laser spectroscopy by comparing it to simultaneously obtained computed tomographic (CT) scans. Methods: The presented optical technique measures free gases, oxygen (O2), and water vapor (H2O) within human tissue by use of low-power diode lasers. Laser light was sent into the tip of the mastoid process
In the capitalist system, there is a need to envision alternatives that advocate for a more just and sustainable world. Alternative scholarships, such as degrowth, aim to counter the hegemonic narrative of food commodification by promoting practices that put social and environmental well-being at the forefront. This ethnographic research outlines the alternative strategies of tackling food waste a
This study investigates the experiences of individuals who have left a criminal lifestyle and the factors influencing their journey. Through interviews with both individuals active in a criminal lifestyle and those who have successfully transitioned to a law-abiding life, this research explores the motivations for leaving a criminal lifestyle and the challenges faced during this process. Key findi
The Bangladeshi Gen Zs and university students demonstrated a revolutionary example of civic engagement, participatory culture, subcultural identity formation, and reformation during the Student Quota Reform Movement in July, leading to the July massacre where thousands of protesting students were tortured and shot to death in public. The movement happened as an enraged response against the announ
As the COVID-19 pandemic spread across the globe, unprecedented policy measures were implemented by central banks and governments to dampen the effect on the real economy. Alongside the spread of the pandemic, research regarding how to simulate similar effects of the virus on the real economy and how to formulate optimal policy began spreading at an equal pace. The aim of this thesis is twofold. I
The most common controller in the process industry today is the PID controller due to its simple structure. A regular factory may have thousands of different PID controllers in use where each of them has to be tuned to work satisfactory. Doing this manually can become both a difficult and time consuming task where some knowledge for each process is required. Therefore, it is highly beneficial to h
Three-dimensional (3D) city models are increasingly utilized among stakeholders of different sectors, particularly those dealing with building information. 3D city models are a three-dimensional digital representation of urban structures, most prominently buildings. They offer diverse applications and have gained wide acceptance as a support tool in planning practices. The push to achieve greater
The covid pandemic has put light on a trend of office buildings experiencing more vacancy than ever before, given our working habits have been forced to shift from occurring predominantly in an office to mainly being pursued from our private homes. This project foresees a future where working remotely has become the new normal and proposes a residential program in an existing office structure, giv
Hematopoietic stem cells (HSCs) are of great importance for the body and can be used to treat diseases such as leukemia or autoimmune conditions. To be able to use HSCs more extensively in therapies we need to know more about how they are being regulated, one way to do this is by knocking down genes with RNA interference. In this project we test a new micro RNA (miRNA), called miR30E, to investiga
In response to growing social injustices in cities, bottom-up initiatives are increasingly recognised as sites of resistance and experimentation. I examine how the PARKS project in Hamburg, a temporary, collectively governed green space, challenges neoliberal urban development and envisions socially just green spaces. Adopting a case study approach, I draw on semi-structured interviews, participan
The increase in contact resistance within battery systems remains poorly understood, despite being one of the primary contributors to battery degradation. This project aims to investigate this phenomenon by modeling the electrical interface as a contact between a pin and a busbar. The main goal is to build a DOE and machine learning framework, using Bayesian optimization to efficiently explore the
This thesis investigates how startups in Tier 2 European cities achieve sustainable growth by engaging with their local entrepreneurial ecosystems. While prior research has largely focused on major capital cities, this study aims to understand how emerging urban canters with less mature infrastructures can still support high-growth entrepreneurial activity. A qualitative research design was employ
This study investigates the corrosion behavior of a magnesium-zinc (Mg-Zn) alloy in a simulated body-like environment, with the aim of optimizing its degradation rate for biodegradable medical implant applications. These implants are designed to support bone healing and then gradually degrade once no longer needed, thereby eliminating the need for additional surgery. Magnesium alloys are promising
In the evolving landscape of digital entrepreneurship, social media influencers (SMIs) have emerged as strategic actors navigating complex stakeholder environments to sustain long-term business viability. While existing literature extensively addresses branding, authenticity, and audience engagement, it often overlooks the strategic coordination required to manage stakeholder relationships across
Electricity grids are essential to industrialized societies, yet they are increasingly unable to meet the dual demands of increased electrification and electricity system decarbonization. Smart grids offer a solution to these challenges by integrating information and communication technologies into the physical grid. However, despite their potential, smart grid implementations often fail to delive
