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An automated ECG-based method may provide diagnostic support in the management of patients with acute coronary syndrome. The Olson method has previously proved to accurately identify the culprit artery in patients with acute coronary occlusion. Methods The Olson method was applied to 360 patients without acute myocardial ischemia and 52 patients with acute coronary occlusion. Results This study es

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Let N be the number of members in a population. Fix any real number A≥2. We present a sequential search algorithm to estimate the exact value of N, with an error probability of at most exp(−A)+exp(−2A)+exp(−3A), regardless of the value of N.

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Public Procurement for Innovation (PPI) is a powerful, underutilized demand-side innovation policy instrument that can be used to stimulate innovation, meet sectoral policy goals and mitigate grand challenges. Further research is required to analyze how PPI contributes to these goals and how it operates in practice; more case studies are needed to achieve this. We analyze a case of direct developm

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Affinity-based solid-phase extraction (SPE) is an attractive low-cost sample preparation strategy for biomarker analysis. Molecularly imprinted polymers (MIPs) as affinity sorbents offer unique opportunities for affinity SPE, due to their low manufacturing cost and high robustness. A limitation is the prediction of their affinity; therefore, screening of analyte recovery and specificity within a l

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The implementation of an enhanced modelling approach for fibre-reinforced composites is presented which may, in addition to the directional dependency induced by the fibres, allow the capturing of the fibre-bending stiffness. The theoretical framework is based on the introduction of higher-order gradients of the motion function as additional arguments of the energy function such that size effects

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Background and purpose — Patient-reported outcome measures (PROMs) are increasingly used to evaluate results in orthopedic surgery. To enhance good responsiveness with a PROM, the minimally important change (MIC) should be established. MIC reflects the smallest measured change in score that is perceived as being relevant by the patients. We assessed MIC for the Self-reported Foot and Ankle Score (

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Microfluidic techniques were applied to the separation of parasite and parasite-infected cells from blood to facilitate the detection of leishmaniasis, a disease representing a high burden in the developing world and for which new diagnostic tools are urgently needed. Leishmania mexicana promastigotes were successfully separated from red blood cells in a deterministic lateral displacement device.

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An analysis on selecting cutting speed, cutting feed and depth of cut when collecting data for the Colding Tool Life Model based on Woxen's Equivalent Chip Thickness was performed to achieve the lowest possible model error. All possible combinations of a large data set were evaluated with regard to model error. This work shows that an increase of ratio between the highest and lowest cutting speed,

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During the past one and a half decades ambient pressure x-ray photoelectron spectroscopy (APXPS) has grown to become a mature technique for the real-time investigation of both solid and liquid surfaces in the presence of a gas or vapour phase. APXPS has been or is being implemented at most major synchrotron radiation facilities and in quite a large number of home laboratories. While most APXPS ins

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Introduction: Product-oriented environmental law is an expanding, poly-thematic subsection of environmental law. First, an increasing number of policy instruments are being used at the international, European and national levels to regulate products, including mandatory performance standards, consumer subsidies, public procurement practices, product bans, taxes and charges and various kinds of man

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A prototype of a surface emissions trap, a new device for reducing emissions of volatile organic compounds and particulate matter from surfaces while allowing evaporation of moisture, was used to improve the indoor air quality of a school building with elevated air concentrations of 2-ethyl-1-hexanol. A clear improvement of the perceived air quality was noticed a few days after the trap had been a

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The starch industry is a key sector of the European food industry with an annual turnover of approx. €4 billion. The production processes in the starch industry are still dominated by conventional separation processes such as evaporators, separators and rotary vacuum filters (RVFs). Membrane processes are only rarely used. This presentation will show how membrane processes can be used to optimise

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This paper evaluates the utility of the feedback particle filter (FPF) for state estimation of SE(2)-configured dynamics in a real-time context. The filter is implemented in discrete time to fuse gyroscopic-and accelerometer measurements with Ultra-Wideband (UWB) and camera measurements. With this state information, the FPF is compared to other common filters in terms of the estimate mean square e

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Membrane processes, antibiotics, enzymes, biofuels and biochemicalsThe end of the 20th century was marked by the start of the third and so far final wave of biotechnology, the so-called white biotechnology, aiming to substitute chemical processes based on C2/C3 chemistry of oil and gas by biotechnological processes. The standard conversion process in biotechnology is fermentation, which is used t

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Objective: To describe the design and rationale for the genetic analysis of acute and chronic cerebrovascular neuroimaging phenotypes detected on clinical MRI in patients with acute ischemic stroke (AIS) within the scope of the MRI-GENetics Interface Exploration (MRI-GENIE) study. Methods: MRI-GENIE capitalizes on the existing infrastructure of the Stroke Genetics Network (SiGN). In total, 12 inte

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It is a human fundamental to desire to be valued, loved and respected - to be significant. Social exclusion induce significance loss which elicits a 'quest for significance' - the search for opportunities to re-gain significance. The present article establishes this relation in a laboratory experiment (N = 71, mean age = 28, SD = 10.42, 65% women, 35% men), showing that socially excluded individua

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The estimation of dynamic panel data models with interactive effects and moving average errors is considered. This is accomplished by making an extension to the factor analytical (FA) estimator which was originally designed for dynamic panels with fixed effects only and serially uncorrelated errors. The results show that the additional allowances have no effect on the asymptotic properties of the

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Studies conducted in historical populations and developing countries have evidenced the existence of clustering in infant deaths, which could be related to genetic inheritance and/or to social and cultural factors such as education, socioeconomic status or parental care. A transmission of death clustering has also been found across generations. One way of expanding the knowledge on intergeneration