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The World Health Organization declared COVID-19, the infectious disease caused by the coronavirus SARS-CoV-2, a pandemic on March 12, 2020. COVID-19 is causing massive health problems and economic suffering around the world. The European Association for the Study of Obesity (EASO) promptly recognised the impact that the outbreak could have on people with obesity. On one side, emerging data suggest
This research monograph explores new frontiers in Markov chains. Although time-homogeneous Markov chains are well understood, this is not at all the case with time-inhomogeneous ones. The book, after a review on the classical theory of homogeneous chains, including the electrical network approach, introduces several new models which involve inhomogeneous chains as well as related new types of rand
This thesis investigates the role of trust in the context of decentralised finance (DeFi). Representing a new paradigm shift in finance, DeFi emerge from the technological developments that we have witnessing in the last decades, particularly decentralised ledger technologies (DLTs) of which Blockchain is perhaps the most popular. DeFi is changing the way that firms raise financial capital and a c
The purpose of this thesis’ topic is to investigate the evolutionary dispersal of the Charon’s fee or Obolus rite outside the Roman provinces in Northern Europe, with a specific focus on Roman Iron Age and Migration Period Scandinavia. The aim of this study is therefore to add further understanding to the spread of Roman cultural influences outside the imperial borders and what made Roman material
The aims of this work are to better understand (1) the relation between exposure and the risk of an accident between pedestrians and motorized vehicles and between bicyclists and motorized vehicles occurring at urban intersections and (2) how the speed environment and the victim´s age relate to the injury severity/outcome once a pedestrian or a bicyclist has been struck by a motorized vehicle. Cro
This research uses data from observations of 8277 motorcyclists at various types of roads of the road hierarchy in Malaysia in 2015, to investigate the effects of road characteristics, motorcyclists’ riding behaviour, motorcyclists’ and motorcycles’ characteristics on the occurrence of riding with excessive speed. For data collection and analysis, new software, i.e. MECHROM, was developed. The spe
Flight is an expensive form of locomotion, but also offers the ability to travel great distances at relatively low cost. Birds have developed various adaptations for optimizing flight performance. The main aim of this thesis is to identify how morphological variables in birds affect aerodynamic drag and flight performance. To this end I studied the aerodynamic performance of a jackdaw (Corvus mone
The dendritic cell (DC) lineage encompasses a diverse population of cells with unique subtype-specific functions. In peripheral blood, four DC subsets have been identified based on their distinct expression of CD1c, CD141, CD16, and CD123, and these subpopulations exhibit functional properties in immune responses. However, their respective roles in allergic diseases, such as rhinitis, are unclear.
Factor H is an inhibitor of the complement system, essential for controlling the alternative pathway and also playing a crucial role in various cellular functions. In this thesis, we identified new intriguing functions of FH as a survival factor for primary human monocytes, promoting their differentiation into immunosuppressive macrophages. We showed that FH is expressed by human breast cancer cel
After electrophoresis of an alkaline extract of type 15 group A streptococci, three main precipitation lines were obtained in diffusion experiments against commercial human polyclonal IgG (lines 1, 2 and 3). Nineteen of 23 sera (83%) from apparently healthy human individuals gave line 3, while 6 of them (26%) gave line 1. The sera giving line 1 did also give line 3. Line 2 was obtained with 2 sera
Evaluating the trade interdependence among countries is the key to understanding critical metal minerals security. By constructing a novel interdependence network, this paper reveals a more comprehensive world hierarchy and risk system of critical metals, and focuses on the interdependencies between China and the US-led MSP countries before and after the Sino-US trade disputes. The results indicat
Bacterial infections represent a serious health care problem, and all multicellular organisms have developed defense mechanisms to eliminate pathogens that enter the host via different paths including wounds. Many invertebrates have an open circulatory system, and effective coagulation systems are in place to ensure fast and efficient closure of wounds. It was proposed early on that coagulation sy
