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The Bicoid (Bcd) protein gradient in Drosophila serves as a paradigm for gradient formation in textbooks. To explain the generation of the gradient, the ARTS model, which is based on the observation of a bcd mRNA gradient, proposes that the bcd mRNA, localized at the anterior pole at fertilization, migrates along microtubules (MTs) at the cortex to the posterior to form a bcd mRNA gradient which i
Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by tau and amyloid brain pathology. With the gradual degeneration of neurons, cognitive symptoms will arise and the affected individual will eventually develop AD dementia. The neuropathologic hallmarks of AD have been observed also in cognitively healthy individuals, which has led to the assumption that the disorde
Climate change is likely to have severe effects on water availability in Ethiopia. The aim of the present study was to assess the impact of climate change on the Gilgel Abay River, Upper Blue Nile Basin. The Statistical Downscaling Tool (SDSM) was used to downscale the HadCM3 (Hadley centre Climate Model 3) Global Circulation Model (GCM) scenario data into finer scale resolution. The Soil and Wate
The ATLAS detector is used to search for high-mass states, such as heavy charged gauge bosons (W'. W*), decaying to a charged lepton (electron or muon) and a neutrino. Results are presented based on the analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 36 pb(-1). No excess beyond standard model expectations is observed. A W' with sequential
The United States has the highest incarceration rate in the world. The phenomenon of mass incarceration largely confines minorities and people living in poverty. More than 600,000 prisoners are released yearly to face barriers of reentering society. Struggles of finding employment, housing, and being denied social services, due to their criminal record, generate a system where former inmates becom
With the rise of serious environmental threats brought about by climate change, governments, organizations, leaders, and academics are constantly seeking ways to address this growing concern, and the development of a circular economy model is seen as a viable solution towards ensuring environmental sustainability alongside economic growth. The concept of circular economy has been defined in a mult
Belgium is celebrated for its progressive LGBTI legislation, ranking second on the ILGA index. At the same time Belgian LGBTQIA+ people experience alarmingly high rates of violence and fear. This thesis examines two competing narratives about the relationship between LGBTI legislation and LGBTQIA+ experiences of safety: (1) ‘LGBTQIA+ safety requires state protection’; and (2) ‘LGBTQIA+ safety requ
Great investments are planned in the north of Sweden the coming years, not the least in the county of Norrbotten where the projects collectively are referred to as the green transition due to the focus on fossil-free techniques. But to be able to secure a sustainable energy supply and reach the goal set by the member states of the European Union of a carbon dioxide neutral union in 2050 the produc
Syftet med uppsatsen är att presentera möjligheter att hänföra en PMSCs (Private Military and Security Company) överträdelser av internationell rätt till en kontrakterande Stat. Uppsatsen fokuserar på relevanta bestämmelser i ARSIWA som det huvudsakliga rättsliga ramverket för Statsansvar. Uppsatsen presenterar definitionen av PMSCs och relevanta egenskaper rörande dess arbetssätt och organisationThe aim of the thesis is to present the possibilities of attributing the unlawful conduct of a Private Military and Security Company (PMSC) to a contracting State. It focuses on relevant provisions of ARSIWA as the main legal framework on State responsibility for wrongful acts. It will focus on relevant characteristics of PMSCs that contribute to the assessment of these entities under the law of a
The research explores the protections provided for migrant domestic workers who are highly undervalued and often exposed to trafficking, despite comprising an integral part of the labour force worldwide. Saudi Arabia is a focus destination country for the study, as it emerged from among the top destination countries absorbing 61 percent of recorded Ethiopian migrant domestic workers. Despite such
The underlying values people hold in relation to the environment is an important aspect to consider when natural areas are shared. These underlying values, so called value orientations, and differences in values directed towards a natural phenomenon can impact views on suitable management, lead to disagreements and even conflict. Understanding of the diverse aspects people value can therefore be i
Under de senaste åren har södra halvklotet och den vidsträckta Södra oceanen fått ökad upp-märksamhet och betydelse inom det vetenskapliga samfundet med avseende på globala klimatförändringar och den globala CO2-cykeln, särskilt vad gäller förhållandena under senaste istidsmaximum (Last Glacial Maximum, LGM) och holocen. Man menar att Västvindbältet på södra halvklotet (Southern Hemisphere WesterlIn recent years, the Southern Hemisphere (SH) and the vast Southern Ocean (SO) have gained awareness and importance within the scientific community in relation to global climate change and the global CO2 cycle, par-ticularly since the Last Glacial Maximum (LGM) and into the Holocene. It is believed that the Southern Hemi-sphere Westerlies (SHW) play a key role in regulating climate change in the m
Type 2 diabetes mellitus (T2DM) in children and adolescents is increasing in the world and the United States of America (US). Previous research has shown that the nurse has an important role in the management of T2DM in children and adolescents but few studies has covered how the nurses perceive and experience this role. This paper aimed to describe how nurses in the US experience their role and t
Over the past 150 years, industrialization, globalization and population growth have altered the planet and its natural conditions at a rapid pace. In this new era, the Anthropocene, environmental degradation has come to a state where sustainable ecosystem management has developed into an urgent quest for humans to maintain their own life-support system. The ecosystem services (ES) concept, initia
Olympic legacy was previously seen as a potential burden on the host city, however an evolutionary shift has occurred whereby it can now be regarded as an instrument in wider urban policy planning. Sustainable development is a requirement set by some governments, and London 2012 aimed to use the Olympic legacy for sustainable development in the form of urban regeneration. This paper is a case stud
Payments for ecosystem services (PES), a mechanism of incentives or compensation to landowners for provision of ecosystem services, have grown as a tool for meeting conservation goals. The Costa Rican payments for ecosystem services (PSA) program is one of the best-known examples because of being one of the most established. Despite this, the PSA program and many other PES programs do not monitor
