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https://www.keg.lu.se/en/sites/keg.lu.se.en/files/utvc11_ht_2016_schedule_20150610_1.pdf - 2026-07-04

Several experimental evidences suggested that beta1 integrin-mediated adhesion of hematopoietic stem cells (HSC) is important for their function in the bone marrow (BM). Using induced deletion of the beta1 integrin gene restricted to the hematopoietic system, we show that beta1 integrin is not essential for HSC retention in the BM, hematopoiesis, and trafficking of lymphocytes. However, immunizati

To promote industrial development and economic growth is a vital issue for governments all over the world. The ideals guiding policymakers in their endeavours, strongly influenced by traditional economics and the innovation system approach, are that innovations based on new and advanced knowledge are central for industrial and economic development. As is exemplified through the quote below policym

There is (or should be) an archived specimen, a reference copy if you like, for all living and fossil species that have been described scientifically. These physical specimens, so-called name-bearing type specimens, are housed at museums or academic institutes around the world for researchers to study and perhaps compare with their own material. But what about our own species, Homo sapiens?.

The aim of this paper was to examine how useable and inclusive the city is from the perspective of older bicyclists. Methods used were quantitative questionnaires and qualitative focus group interviews. Participants were people aged 65 years or older. The results showed that respondents were fairly satisfied with the transport infrastructure design. However, other road users seemed to complicate c

In recent years, scientists have advocated the use of targeted therapies in the form of drugs that modulate genes and proteins that are directly associated with cancer progression and metastasis. Malignant melanoma is a dreadful cancer type that has been associated with the rapid dissemination of primary tumors to multiple sites, including bone, brain, liver and lungs. The discovery that approxima

During mammalian ocular development, several signaling pathways control the spatiotemporal highly defined realization of the three-dimensional eye architecture. Given the complexity of these inductive signals, the developing eye is a sensitive organ for several diseases. In this study, we investigated a Dkk1+/- haploinsufficiency during eye development, resulting in coloboma and anterior eye defec

While recent LGBT rights demonstrations and discussions about same-sex marriage have thrust the issue of homosexuality into the spotlight, it was not long ago that the issue of homosexuality was notable by its absence in Vietnam. Drawing on semi-structured interviews with young gay, lesbian and bisexual people in Vietnam's capital city Hanoi, this paper considers the increasing visibility of homos

Background: Cognitive functioning may have implications for engagement in daily occupations among people with schizophrenia.Objectives: This cross-sectional study explores relationships between time use assessed occupational engagement and cognitive functioning among persons with schizophrenia.Methods: Thirty-nine participants from four mental health care services in Sweden participated. The Profi

Many nation states in Southeast Asia have ratified human rights conventions without abiding by their stipulations. Among factors such as poverty and political disinclination something which has widely been called 'Asian values' is seen by some as a reason for why certain human rights laid out in UN conventions are not adhered to. The crux of the conflict is the claim that particular Asian