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BACKGROUND: Although age is associated with increasing blood pressure, there is a substantial heterogeneity within a certain birth cohort. Whether increase in systolic and diastolic blood pressure is related to pulmonary function is largely unknown. OBJECTIVE: To study blood pressure elevation between 55 and 68 years of age in relation to vital capacity (VC) and forced expiratory volume (FEV1.0) a
Activated protein C (APC) is a serine proteinase that regulates blood coagulation. In plasma it is inhibited mainly by the protein C inhibitor (PCI). The plasma concentrations of APC-PCI complex is increased in hypercoagulative states such as deep venous thrombosis. Formation of the APC-PCI complex induces a drastic conformational change in PCI that exposes new epitopes (neoepitopes) on the molecu
Trabecular bone is viscoelastic under dynamic loading. However, it is unclear how tissue viscoelasticity controls viscoelasticity at the apparent-level. In this study, viscoelasticity of cylindrical human trabecular bone samples (n = 11, male, age 18–78 years) from 11 proximal femurs were characterized using dynamic and stress-relaxation testing at the apparent-level and with creep nanoindentation
This research explores the development and use of waste to energy (WTE) technologies in Europe and in the Province of Ontario, Canada. As the quantity of waste generated has continued to increase in industrialized countries, the need for alternative waste management methods to reduce the dependency on landfill and to recover the resource in the waste has also increased. Many European countries, in
Objective: Radiographic damage is an important outcome in rheumatoid arthritis (RA). The disease course varies considerably, and there is a need for simple and reliable prognostic markers. The aim of the study was to determine the utility of early signs of extra-articular disease, manifested as rheumatoid nodules (RN), in predicting radiographic outcome. Methods: In a cohort (n = 1589) of consecut
This study sought to compare type 2 diabetes (T2D) risk indicators in Iraqi immigrants with those in ethnic Swedes living in southern Sweden.
It has recently been claimed that older genes tend to evolve more slowly than newer ones (Alba and Castresana 2005). By simulation of genes of equal age, we show that the inverse correlation between age and rate is an artifact caused by our inability to detect homology when evolutionary distances are large. Since evolutionary distance increases with time of divergence and rate of evolution, homolo
Background: The contribution of smoking to rheumatoid arthritis (RA) is hypothesized to be mediated through formation of anti-citrullinated protein antibodies (ACPA). In RA, however, autoantibodies such as ACPA, rheumatoid factor (RF), and anti-carbamylated protein antibodies (anti-CarP) often occur together, and it is thus unclear whether smoking is specifically associated with some autoantibodie
To the memory of Carl W. Ossén.
This report summarises the most important lessons learned from the research project From waste management to waste prevention. In the research project, researchers from Lund University and the University of Gothenburg, but also Umeå University and the Royal Institute of Technology, have studied waste prevention.The aim of the project has been to identify and clarify the difficulties in realising t
During the last couple of decades, we have witnessed a proliferation of the project as an organizational solution in sectors as diverse as IT, housing, social services, education and culture. Despite a growing interest in the phenomenon, we know surprisingly little of how processes of public sector projectification unfold in practice, especially at local government level. This article uses an inst
Parental dying is a life changing experience for children. This study explores children’s strategies and (inter)actions in their everyday life when facing critically ill parents and imminent death, from the children’s and parents’ perspectives. A qualitative systematic review was carried out, registered in PROSPERO (CRD42022306862). A literature search and screening in six databases resulted in ei
The aim of this thesis is to present issues related to cross-border taxation of employee stock options and critically inquiring whether the Swedish Supreme Administrative Court’s reasoning about comparable situations in the two rulings concerning taxation of stock options is supported by ECJ case law. On 4th of November 2015, the Supreme Administrative Court in Sweden issued two rulings concerning
In many urban spaces in the United States, the personal vehicle continues to shape the landscape in unsustainable ways that prioritize the economically and socially dominant groups in society and cater to urban sprawl. Equitable access to density-promoting public transportation is often marginalized, creating transportation challenges for economically and socially disadvantaged groups. Throughout
This thesis explores the dynamics of relationships, focusing on the themes of love, unpaid labour and unequal division. This research examines how traditional gender roles and societal expectations shape the experiences of individuals within heterosexual relationships in Sweden. Through a qualitative methodology, including semi-structured interviews and thematic analysis, the study reveals the mul
This thesis explores the impact of extreme weather events during gestation and infancy on multiple outcomes, especially early labour income. The subjects are Indian children born between 1993/94 from the Young Lives longitudinal study. The weather shocks are extracted from the NOAA geo-referenced weather data. Thanks to Mediation Analysis methodology applied, not only the Direct Effects of early l
