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Fibre directions at a branch-stem junction in Norway spruce : a microscale investigation using X-ray computed tomography

The connection between branch and trunk in a tree must be strong enough to transfer all loads acting on the branch, and it is well known that such branch-stem connections are indeed very strong. In this paper, X-ray computer tomography is employed to investigate the local fibre orientation in the close surrounding of a knot in a Norway spruce specimen to better understand the origins of the mechan

Combined Estrogen Alpha and Beta Receptor Expression Has a Prognostic Significance for Colorectal Cancer Patients

We reported that high estrogen receptor beta (ERβ) expression is independently associated with better prognosis in female colorectal cancer (CRC) patients. However, estrogen receptor alpha (ERα) is expressed at very low levels in normal colon mucosa, and its prognostic role in CRC has not been explored. Herein, we investigated the combined role of ERα and ERβ expression in the prognosis of female

Study of risk factors for injuries due to cardiopulmonary resuscitation with special focus on the role of the heart : A machine learning analysis of a prospective registry with multiple sources of information (ReCaPTa Study)

Background: The study of thoracic injuries and biomechanics during CPR requires detailed studies that are very scarce. The role of the heart in CPR biomechanics has not been determined. This study aimed to determine the risk factors importance for serious ribcage damage due to CPR. Methods: Data were collected from a prospective registry of out-of-hospital cardiac arrest between April 2014 and Apr

Risk of prostate cancer death in men diagnosed with prostate cancer at cystoprostat-ectomy. A nationwide population-based study

BACKGROUND AND AIMS: One out of three men who undergo cystoprostatectomy for bladder cancer is diagnosed with incidental prostate cancer (PCa) at histopathological examination. Many of these men are PSA tested as part of their follow-up, but it is unclear if this is needed. The aim of this study was to assess the risk of PCa death in these men and the need of PSA-testing during follow-up. METHODS:

Welfare Technology in Practice : A Survey-Based Analysis of User Satisfaction, Expectations, and Needs

There is growing interest in using digital technology like welfare technology (WT) to support older adults (aged 75+) to age in place, particularly in Nordic countries. This cross-sectional survey study (n = 414), conducted in 18 Swedish municipalities, used descriptive statistics and binary logistic regression to examine: user experiences related to satisfaction with WT, as well as users’ expectaThere is growing interest in using digital technology like welfare technology (WT) to support older adults (aged 75+) to age in place, particularly in Nordic countries. This cross-sectional survey study (n = 414), conducted in 18 Swedish municipalities, used descriptive statistics and binary logistic regression to examine: user experiences related to satisfaction with WT, as well as users’ expecta

Ash application enhances decomposition of recalcitrant organic matter

Harvesting whole-tree biomass for biofuel combustion intensifies removal of nutrients from the ecosystem. This can be partly abated by applying ash from the combustion back to the system, as the ash is rich in nutrients. Ash is very alkaline and ash application raises soil pH, which in turn can stimulate microbial activity and thus decomposition and mineralization. Our aim was to test if ash induc

Is road-side fishpond water in Bangladesh safe for human use? An assessment using water quality indices

Pond water is used in everyday life by many people in Bangladesh, however, without sufficient and reliable information regarding water quality and pollution status. For this reason, geospatial analysis and mapping of water quality indices such as metal (MI), contamination (Cd), and physicochemical water quality index (WQI) were assessed to improve the understanding of potential pollution sources.

The absence of women’s voices in Hofstede’s Cultural Consequences: A Postcolonial Reading

Along with the increasingly globalized business environment that we have witnessed over the past decades cross-culture management research has establish itself as an important research field with much of its inspiration coming from colonialism and a Western rational thinking. The legacy of colonialism and Western rationality is apparent in its engagement in research practices involving the essenti

Phenotype and genotype in 52 patients with Rubinstein–Taybi syndrome caused by EP300 mutations

Rubinstein–Taybi syndrome (RSTS) is a developmental disorder characterized by a typical face and distal limbs abnormalities, intellectual disability, and a vast number of other features. Two genes are known to cause RSTS, CREBBP in 60% and EP300 in 8–10% of clinically diagnosed cases. Both paralogs act in chromatin remodeling and encode for transcriptional co-activators interacting with >400 prote

Prognostic significance of clinical seizures after cardiac arrest and target temperature management

Aim: Clinical seizures are common after cardiac arrest and predictive of a poor neurological outcome. Seizures may be myoclonic, tonic-clonic or a combination of seizure types. This study reports the incidence and prognostic significance of clinical seizures in the target temperature management (TTM) after cardiac arrest trial. Our hypotheses were that seizures are associated with a poor prognosis

Waste Viscose for Optically pure Lactic acid Production

Recycling of textile fibers is a mandatory step in the life-cycle of fabrics to avoid incineration or landfilling. After fiber-to-fiber recycling, cellulose fiber saccharification opens the door to the production of biochemical building blocks through microbial fermentation. This study documents for the first time the production of optically pure D-lactic acid (D-LA), one of the precursors of poly

Genome-wide structural and functional protein characterization by ab initio protein structure prediction

Popular Abstract in Swedish Många av alla kemiska processer som pågår i våra kroppar utförs av proteiner. När de inte fungerar blir vi sjuka. I vissa fall, till exempel vid Alzheimers sjukdom eller Creutzfeld Jacobs sjukdom, beror det på att ett visst protein har fel form. Att förstå hur proteiner antar sin slutliga form och vad det har för inverkan på proteinets funktion är således viktigt. ÅVery little is known about a considerable part of all proteins and it is time consuming and expensive to study each individual protein to determine its function, structure and cellular role. Proteins retain structural, functional and sequential characteristics from ancestral proteins and hence two proteins that share a common ancestor, i.e. are homologs, will to some extent have similar sequen

Marieberg och 1700-talets kakelugnar

The Marieberg porcelain factory, situated on the island of Kungsholmen in Stockholm, existed between 1758 and 1788. The aim of this study has been to investigate the manufacture of tiled stoves at Marieberg. The first question I wanted to answer was: how many were actually produced? The few documents from the period that have survived show that Marieberg must have had continuous production of tile

Task based exposure assessment in ergonomic epidemiology: a study of upper arm elevation in the jobs of machinists, car mechanics, and house painters

Aims: To explore the precision of task based estimates of upper arm elevation in three occupational groups, compared to direct measurements of job exposure. Methods: Male machinists (n = 26), car mechanics ( n = 23), and house painters ( n = 23) were studied. Whole day recordings of upper arm elevation were obtained for four consecutive working days, and associated task information was collected i

Co-responsibility and Causal Involvement

In discussions of moral responsibility for collectively produced effects, it is not uncommon to assume that we have to abandon the view that causal involvement is a necessary condition for individual co-responsibility. In general, considerations of cases where there is "a mismatch between the wrong a group commits and the apparent causal contributions for which we can hold individuals responsible"

Complications and survival after surgical treatment of 214 metastatic lesions of the humerus

Background: The humerus is the second most common long-bone site of metastatic bone disease. We report complications, risk factors for failure, and survival of a large series of patients operated on for skeletal metastases of the humerus. Materials and methods: This study was based on 208 patients treated surgically for 214 metastatic lesions of the humerus. Reconstructions were achieved by intram

Molecular Genetic Characterization of Acute Lymphoblastic Leukemia with a Poor Prognosis

Popular Abstract in Swedish Leukemi kännetecknas av en okontrollerad tillväxt av omogna vita blodkroppar och orsakas av förvärvade genetiska förändringar. Genetiska förändringar eller avvikelser, som är drivande i cancerutvecklingen, uppstår när normala celler delar sig. Identifiering av sådana förändringar på gen-och kromosomnivå är av stor klinisk betydelse. Behandling styrs av vilka genetiska aAcute lymphoblastic leukemia (ALL) affects individuals at all ages, with peak incidences in children <4 years and adults >50 years. ALL is broadly categorized into B-cell precursor (BCP) and T-cell ALL with specific clinical features associated with outcome. In contrast to pediatric ALL, which has a favorable prognosis, adult ALL is associated with a much poorer outcome with less than 40% overall

Early Surfactant Guided by Lamellar Body Counts on Gastric Aspirate in Very Preterm Infants

Background: We have developed a rapid method, based on lamellar body counts (LBC) on gastric aspirate, for identifying newborns who will develop respiratory distress syndrome with a need for surfactant supplementation. Objective: We set out to test whether it was possible to improve the outcome when used in a clinical trial. Methods: We randomly assigned 380 infants born at 24-29 weeks' gestation

The association between common vitamin D receptor gene variations and osteoporosis : a participant-level meta-analysis

BACKGROUND: Polymorphisms of the vitamin D receptor (VDR) gene have been implicated in the genetic regulation of bone mineral density (BMD). However, the clinical impact of these variants remains unclear.OBJECTIVE: To evaluate the relation between VDR polymorphisms, BMD, and fractures.DESIGN: Prospective multicenter large-scale association study.SETTING: The Genetic Markers for Osteoporosis consor

Influence of window size on the energy balance of low energy houses

A generally accepted way of building passive houses has been to have small windows facing north and large windows to the south. This is to minimize losses on the north side while gaining as much solar heat as possible on the south. ln spring 2001, 20 terraced houses were built outside Gothenburg partly in this way. The indoor temperature is kept at a comfortable level by passive methods, using sol