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OBJECTIVES: To evaluate the prophylactic efficacy of the human papillomavirus (HPV) quadrivalent vaccine in preventing low grade cervical, vulvar, and vaginal intraepithelial neoplasias and anogenital warts (condyloma acuminata). DESIGN: Data from two international, double blind, placebo controlled, randomised efficacy trials of quadrivalent HPV vaccine (protocol 013 (FUTURE I) and protocol 015 (F

Background: Aseptic loosening is one of the major reasons for late revision in total knee arthroplasty (TKA). The risk of aseptic loosening can be detected using radiostereometric analysis (RSA), whereby micromovements (migration) can be measured, and thus RSA is recommended in the phased introduction of orthopedic implants. Decrease in bone mineral density (BMD), as measured by dual-energy x ray

Popular science summary: What the zebra finches did not see There is more out there than what we can see; that is something that most people would agree on. And I am not talking about ghosts from the beyond or aliens from space; I am talking about all those things that we know exist but that we are not able to see with our own eyes or feel with our own senses. I am not talking science fiction, I

We study an extended bootstrap percolation process in several steps in dimension one, assuming noncyclic boundary conditions. We study the asymptotic behavior of the process as the size of the underlying graph goes to innity. We nd a phase transition with respect to the initial conditions. The phase diagram on the set of initial conditionals of the extended process is described completely. This pr

Syftet med denna framställning är att, mot bakgrund av att arvsrätt existerar inom äktenskap, undersöka om sambors avsaknad av arvsrätt är motiverad samt att diskutera sambors efterlevandeskydd de lege ferenda. För att uppnå syftet undersöks efterlevandeskyddet för sambor respektive makar, hur efterlevandeskyddet för sambor kan stärkas, hur sambors avsaknad av arvsrätt är motiverad och till sist hThe purpose of this thesis is to investigate whether or not it is justifiable that cohabiting partners don’t inherit from each other, given that married couples do. Furthermore, I am going to discuss cohabiting partners’ provision for surviving lex ferenda. Towards this purpose I will look into current survivorship legislation that affects cohabiting partners as well as married couples, how it can

The paper reviewed a collection of studies from 2015-2025 in Sweden on municipal organizational change, with the aim of discussing challenges and benefits during modern change processes and connecting it to previously existing theories. The results showed that there is some conflict between different governance models (mainly NPM and TBG), that TBG can be implemented differently in different munic

Lund University presentation Lund University 2026 | EDUCATION, RESEARCH AND COLLABORATION SINCE 1666 Welcome to Lund University!   The image shows the Main University Building from 1882, designed by Helgo Zettervall. The sphinxes on the roof are popular symbols of the University.   The building has a grand auditorium that is used for ceremonies, concerts, etc. The building also housed the Vice-Cha

https://www.staff.lu.se/sites/staff.lu.se/files/2026-04/LU-presentation-2026-ENG-1.pptx - 2026-05-19

Antibiotic resistance poses a global threat. Antibiotics are administered to 80-90% of terminally ill patients but evidence of their effectiveness in improving survival or symptom relief at the end of life (EOL) is scarce. To determine the proportion of deceased patients that continue antibiotic treatment after documented EOL discussion and the decision to prioritise symptom relief over active tre

BackgroundImmune-related hepatitis (ir-hepatitis) ranks among the most frequent adverse events of immune checkpoint inhibitors (ICIs). Limited knowledge exists regarding the incidence, characteristics, and treatment of patients having an inadequate response to initial therapy with steroids. Characterizing ir-hepatitis phenotypes and treatment responses can provide valuable insights for guiding tre

Background: Early-onset pancreatic cancer (< 50 years, EOPC) is uncommon and limited data exist on clinical presentation and long-term survival. The aim of this study was to compare outcomes between patients with EOPC and those with later-onset pancreatic cancer (≥ 50 years, LOPC) using a large population-based cohort. Methods: The Surveillance, Epidemiology, and End Results (SEER) database was qu

Within the common market, built upon the notion of free movement of goods and undistorted competition, Member States are prohibited to put restrictions on the free market or distort competition if no justifiable reasons under Community Law are presented. Thus, state monopolies of a commercial character are per se controversial within the Common market. However it is clear from the existence of Art

Sammanfattning I Sverige råder fri bevisprövning med fri bevisvärdering. Det innebär att inga formella regler uppställs för hur ett bevis ska värderas eller vilka metoder som ska tillämpas av domstolen vid bevisvärderingen. Således är det teoretiskt möjligt att vid en ord mot ord situation finna det ställt utom rimligt tvivel att den tilltalade gjort som åklagaren gör gällande. Trots detta är det Summary In Sweden there is a free sifting of evidence with a free evaluation of evidence. This means that no formal rules are imposed on how evidence should be valued or the methods to be applied by the court at the evaluation of evidence. It is theoretically possible to find it beyond reasonable doubt that the accused made as the prosecutor alleges in a situation where one word stands against ano

Förevarande arbete har som målsättning att utreda huruvida en förändring i dödsstraffsdebatten skedde under 1800-talet och 1900-talets första decennier intill dess avskaffande 1921. För att på ett bra sätt kunna företa en sådan granskning inleds uppsatsen med ett avsnitt som kortfattat beskriver den svenska historien för att därefter följas av ett avsnitt enbart rörande dödsstraffsdebatten och avThe goal of the following essay is to investigate any changes in the debate regarding the Swedish death penalty which took place during the 19th century and the beginning of the 20th century until the death penalty was abolished in 1921. To be able to undertake such an investigation it’s my personal belief that one first must know the basics of Swedish history. Therefore the essay starts with a

BackgroundLoss to follow-up (LTFU) from tuberculosis (TB) treatment and care is a major public health problem as patients can be infectious and also may develop a multi-drug resistant TB (MDR-TB). The study aimed to assess whether LTFU differs by the distance TB patients travelled to receive care from the nearest health facility.MethodsA total of 402 patient cards of TB patients who received care

BACKGROUND: Patients on dialysis who have an acute myocardial infarction (AMI) have an exceedingly poor prognosis, but it is unknown to what extent guideline-recommended interventions and treatments are used and to which benefit. We aimed to assess temporal changes in the use of treatments and survival rates in dialysis patients with an AMI. METHODS AND RESULTS: All consecutive AMI cases from 1996

BACKGROUND: Although the association between cytosine-adenine-guanine (CAG) repeat length and age at onset of Huntington's disease is well known, improved prediction of onset would be advantageous for clinical trial design and prognostic counselling. We compared various measures for tracking progression and predicting conversion to manifest Huntington's disease.METHODS: In this prospective observa

BACKGROUND: Parkinson's disease is typically treated with oral dopamine replacement therapies; however, long-term treatment leads to motor complications and, occasionally, impulse control disorders caused by intermittent stimulation of dopamine receptors and off-target effects, respectively. We aimed to assess the safety, tolerability, and efficacy of bilateral, intrastriatal delivery of ProSavin,

Sweden of the eighteenth and nineteenth centuries was visited and toured by a number of British author-travellers, whose subsequently published views of and on the country and its people are examined and presented in this thesis. Using as primary sources British-published monographs deriving, wholly or in part, from an experienced Sweden of c.1770-1865, it has been possible to identify and define

Background: The frequent emergence of the re-positive patients with COVID-19 is a potential threat worldwide. This study aimed to describe data from admission to follow-up for patients with COVID-19 and analyze the possible causes for re-positive nucleic acid tests to provide more scientific basis for reducing the numbers of re-positive patients after discharge. Methods: We retrospectively recorde