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For the first time, the experimental and theoretical evidence for the conversion of 4-nitrobenzenethiol (4-NBT) to p,p'-dimercaptoazobenzene (DMAB) in Ag and Cu sols by surface photochemistry reaction is obtained with surface-enhanced Raman scattering (SERS) spectroscopy. The SERS spectrum of 4-NBT in Cu sol is identical to that of DMAB produced from 4-aminothiophenol in Ag sol as reported in rece

Apolipoprotein B (apoB) containing lipoproteins, i.e. VLDL, LDL and Lp(a), are consequently lowered by ACTH treatment in humans. This is also seen as reduced plasma apoB by 20-30% and total cholesterol by 30-40%, mostly accounted for by a decrease in LDL-cholesterol. Studies in hepatic cell line (HepG2) cells showed that apoB mRNA expression is reduced in response to ACTH incubation and is followe

Farnesyl pyrophosphate (FPP) is an intermediate in cholesterol biosynthesis, and it has also been reported to activate platelet LPA (lysophosphatidic acid) receptors. The aim of this study was to investigate the role of extracellular FPP in platelet aggregation. Human platelets were studied with light transmission aggregometry, flow cytometry and [35S]GTPγS binding assays. As shown previously, FPP

After having worked with a project regarding custody procedures and detention facilities where the goal was to give recommendations to the Former Yugoslav Republic of Macedonia (Macedonia) on issues which needed to be changed for them to fulfil the European minimum standard, I doubted that there really existed any European minimum standards. Therefore, I studied Swedish, British, French and Europe

De nuvarande svenska reglerna avseende sakrätt i panträtt är utspridda i olika författningar, vilka tidigare endast har reformerats vid extrem nödvändighet. USA hade tidigare ett regelverk för säkerhetsrätter som i många avseenden var väldigt likvärdigt det regelverk som idag finns i Sverige. Som ett svar på det faktum att de amerikanska reglerna hade uppnått en nivå av otolererbar komplexitet genThe current Swedish rules regarding perfection of liens is fragmented. The system has only undergone partial reform and even then only because of extreme necessity. The U.S. had a security interest system that in many parts were very similar to the system that today is present in Sweden. A reform took place as a response to the fact that the system finally reached the level of intolerable complexi

The President of the United States of America wields executive power like few other heads of state, in being commander-in-chief of the sole military and economic superpower within the international system. Yet after presidency, that hard power dissipates and is instead replaced by the ability to project soft power. In our paper we seek to understand this post-presidential power, the means through

Neo-liberal policy as a means for development has been present in our society since the first experiment in Chile during the 1970s. This experience came to be known as an economic ?miracle? and the model was soon imitated by surrounding countries. In these countries income inequality has been a well-known feature and the Gini Coefficient in all Latin American countries exceeds the world average. T

Life-history strategies emerge from eco-evolutionary constraints, where organisms allocate limited resources to growth, survival, and reproduction, resulting in trade-offs such as the growth–survival trade-off. There is still a limited understanding of whether and how disturbance regimes and successional stages might mediate such trade-offs, with potential consequences for species population dynam

Future exposure to coastal flooding in China is driven more by growing populations and economic activity rather than by rising seas and intensifying storm surges. Policymakers must anticipate these multiple risk drivers to better inform spatial planning and development strategies and to ensure effective, sustainable coastal adaptation.

Males and females exhibit profound differences in immune responses and disease susceptibility. However, the factors responsible for sex differences in tissue immunity remain poorly understood. Here, we uncovered a dominant role for type 2 innate lymphoid cells (ILC2s) in shaping sexual immune dimorphism within the skin. Mechanistically, negative regulation of ILC2s by androgens leads to a reductio

Inflammatory leiomyosarcoma (ILMS) is a soft tissue tumor that morphologically resembles conventional leiomyosarcoma (LMS) admixed with a prominent inflammatory infiltrate. Genetic data on ILMS are still limited but have suggested that this entity is characterized by hyperhaploidy (24-34 chromosomes). This low chromosome number is otherwise uncommon in neoplasia and has been found only in 0.2% to

Even though hematopoietic stem cells (HSC) are characterized by their ability to self-renew and differentiate, they primarily reside in quiescence. Despite the immense importance of this quiescent state, its maintenance and regulation is still incompletely understood. Schlafen2 (Slfn2) is a cytoplasmic protein known to be involved in cell proliferation, differentiation, quiescence, interferon resp

Fatal intoxications with opioids are known to be associated with an increased lung weight, as well as with brain and pulmonary edema and urinary retention. However, there is evidence to suggest that fatal intoxications with non-opioid substances are also associated with increased lung weight; however, the latter aspect has not been comprehensively analyzed. To determine to what extent opioid and n

Galectin-3-dependent clusters or lattices are formed at the surface as well as in distinct organelles of eukaryotic cells. Incorporation into membrane proximal networks can fix glycoproteins within subcellular domains or sort them into distinct transport pathways. In the present paper we analysed the effect of acidification on the sugar binding and self-oligomerization of galectin-3. Using a fluor

Background: The technical skills of a surgeon influence surgical outcome. Testing technical aptitude at point of recruitment of surgical residents is only conducted in a few countries. This study investigated the impact of visuospatial ability (VSA), background factors, and manual dexterity on performance in two different laparoscopic surgical simulators amongst applicants and 1st year surgical re