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Apoptosis is essential to eliminate secretory epithelial cells during the involution of the mammary gland. The environmental regulation of this process is however, poorly understood. This study tested the effect of HAMLET (human alpha-lactalbumin made lethal to tumor cells) on mammary cells. Plastic pellets containing HAMLET were implanted into the fourth inguinal mammary gland of lactating mice f

The high-molecular-mass salivary mucin MG1, one of two major mucins produced by human salivary glands, plays an important role in oral health by coating the tooth surface and by acting as a bacterial receptor. Here this mucin was purified from the submandibular/sublingual saliva of a blood group O individual. The presence of MUC5B as the major mucin in this preparation was confirmed by amino acid

In this study, the file-sharing networks known as private trackers are discussed, which are networks centered around BitTorrent technology. The purpose of the study is to explore how individuals share content on private trackers and discuss how the act of uploading is affected by actors within the file-sharing network. By using actor-network theory, both human and non-human actors that affect the

The purpose of this thesis is to unveil in how far organisations' Employer Branding efforts, concerning Social Media content, meet the expectations of Young Talents. The outcome will aid employers in attracting and retaining Young Talents in their organisation. The theoretical framework of the thesis deals with the three key concepts Employer Branding, Social Media and Young Talents. The con

This thesis is an attempt to identify possible changes in the operational code of the former Swedish minister for foreign affairs Carl Bildt following the Georgian war of August 2008. The analysis uses the VICS (Verbs In Context System) coding scheme developed by Stephen G. Walker, Mark Schafer and Michael D. Young to quantitively analyze public speeches made by Bildt from before and after the war

In this article we investigate transfer in the ab-initio acquisition of grammatical gender in two groups of multilingual learners. The first group knows two gender languages (German and French), which can potentially act as transfer sources; the second group knows three (German, French and Italian). Both groups had to assign gender to nouns in Franco-Provençal, a Romance language which is new to t

As I write this, there are numerous horrible wars and acts of terror taking place all over the world. However, it is my belief that the situation would be even worse without diplomats working as mediators, and for them to be able to fulfil their duties they need to be inviolable. Through the Vienna Convention on Diplomatic Relations of 1961, which is believed to reflect customary international law

Zhu Tianxin’s novella The Old Capital narrates the process of slowly losing contact with the past through forgetting, loss and material erasure. Instead of completely eradicating the past, this process prompts a renewed interest, and, in a sense, a renewed presence of that past in conscious remembering, literary evocation and narrative attendance. Inspired by David Crouch’s conception of heritage

Background and aims: A vulnerable plaque is an atherosclerotic plaque that is rupture-prone with a higher risk to cause cardiovascular symptoms such as myocardial infarction or stroke. Mimecan or osteoglycin is a small leucine-rich proteoglycan, important for collagen fibrillogenesis, that has been implicated in atherosclerotic disease, yet the role of mimecan in human atherosclerotic disease rema

BACKGROUND: Blood loss and adult blood transfusions are common during the neonatal period in preterm infants. The objective of the study was to clarify if degree of loss of fetal haemoglobin (HbF) was associated with later retinopathy of prematurity (ROP).METHODS: Retrospective observational cohort study. In total, 452 infants born <30 gestational weeks at a tertiary level neonatal intensive care

Currently, no effective targeted therapeutics exists for treatment of metastatic prostate cancer (PCa). Given that matrix metalloproteinases 9 (MMP9) and its associated vascular endothelial growth factor (VEGF) are critical for tumor vascularization and invasion under castration-resistant condition, it is therefore of great importance to define the functional association and interplay between andr

The β-cell function in the perfused pancreas, the total pancreatic insulin content, and the weights of pancreas, kidney, spleen, and total body fat were compared at the age of 30 and 45 days in diabetes-prone and body weight-matched diabetes-resistant male BB rats. These inbred rats had an incidence rate of diabetes at 90 days of age of 80 and 0%, respectively. At day 30, the pancreatic insulin co

The aim of this paper is to contribute to the empirical question of the labour organisation and the gender division of labour in a semi-landless rural group, crofters (Swedish torpare), during the nineteenth century, and thereby also add to the larger question of the role of gender division of labour in the formation of a wagedependent class. The crofters’ households performed contract-defined cor

BACKGROUND: Higher body weight is a well-known determinant of the metabolic syndrome (MetS) and its components. It is however less well studied how the change in weight from age 20 years to middle age or old age affects MetS development.METHODS: In the community-based EpiHealth (n = 19,000, age range 45 to 75 years, 56% females) and PIVUS (n = 1000, all aged 70 years, 50% females) studies, the par

The aim of this study was to derive dietary patterns associated with cardio-metabolic traits and to examine whether these predict prospective changes in these traits and incidence of the metabolic syndrome (iMetS). Subjects from the Malmö Diet and Cancer Study cardiovascular cohort without cardio-metabolic disease and related drug treatments at baseline (n 4071; aged 45-67 years, 40 % men) were in

Being aware of nature and its life-supporting functions helps our societies to operate more sustainably.

Background: Rupture of atherosclerotic plaques is the major cause of acute cardiovascular events. The biomarker PRO-C6 measuring Endotrophin, a matrikine of collagen type VI, may provide valuable information detecting subjects in need of intensified strategies for secondary prevention. Objective: In this study, we evaluate endotrophin in human atherosclerotic plaques and circulating levels of PRO-