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In situ hybridization was used to study expression of mRNAs for members of the nerve growth factor (NGF) family in the rat brain after 2 and 10 min of forebrain ischemia and 1 and 30 min of insulin-induced hypoglycemic coma. Two hours after the ischemic insults, the level of brain-derived neurotrophic factor (BDNF) mRNA was markedly increased in the granule cells of the dentate gyrus, and at 24 h
Aims: To investigate whether the N-terminal truncated glutamic acid decarboxylase 65 (GAD65) isoform is as well recognized by people with stiff person syndrome as it is by people with Type 1 diabetes, and whether conformational GAD65 antibody epitopes are displayed properly by the isoform. Methods: GAD65 antibody-positive healthy individuals (n=13), people with stiff-person syndrome (n=15) and chi
We do mean-field perturbation theory for U(1) lattice gauge theory in the axial gauge, and evaluate corrections from fluctuations up to fourth order for the free energy and plaquette energy. Comparing with similar results previously obtained in the Feynman gauge we find, to those orders studied, a gauge dependence of the size of the first correction term neglected with one exception. This gauge de
An expanded record (~14 m)of the Paleocene–Eocene Thermal Maximum (PETM), a transient period of extreme global warming that occurred ~56 million years ago, has been found based on calcareous nannofossil and foraminifera stratigraphy in the deep marine Río Gor section, Subbetic Zone, SE Spain. During the early Palaeogene the Subbetic Zone wa
It has been suggested that sugar intake may play a role in the development of atherosclero-sis. However, studies on this matter are lacking. Intima media thickness (IMT) is a well-established measurement of subclinical atherosclerosis. This study aimed to investigate the cross-sectional association between sugar intake (i.e., added, free and total sugar and sugar-rich foods and beverages) and IMT.
A search for supersymmetry in events with four or more charged leptons (electrons, muons and τ-leptons) is presented. The analysis uses a data sample corresponding to 139 fb−1 of proton-proton collisions delivered by the Large Hadron Collider at s = 13 TeV and recorded by the ATLAS detector. Four-lepton signal regions with up to two hadronically decaying τ-leptons are designed to target several su
Results of a search for new physics in final states with an energetic jet and large missing transverse momentum are reported. The search uses proton-proton collision data corresponding to an integrated luminosity of 139 fb-1 at a center-of-mass energy of 13 TeV collected in the period 2015-2018 with the ATLAS detector at the Large Hadron Collider. Compared to previous publications, in addition to
BACKGROUND: Takotsubo syndrome (TS) is a potentially life-threatening acute cardiac syndrome with a clinical presentation similar to myocardial infarction and for which the natural history, management, and outcome remain incompletely understood. Our aim was to assess the relative short-term mortality risk of TS, ST-segment–elevation myocardial infarction (STEMI), and non-STEMI (NSTEMI) and to iden
A search for new phenomena is presented in final states with two leptons and one or no b-tagged jets. The event selection requires the two leptons to have opposite charge, the same flavor (electrons or muons), and a large invariant mass. The analysis is based on the full run-2 proton-proton collision dataset recorded at a center-of-mass energy of s=13 TeV by the ATLAS experiment at the LHC, corres
CONTEXT: The epidemiological signature of renal cell carcinoma (RCC) during the past decades is explained by overdetection and overtreatment of indolent cancers; furthermore, a non-negligible proportion of patients undergoing surgery for suspected RCC harbour benign renal tumours. As the gold standard for RCC diagnosis remains histopathological analysis of surgical or biopsy specimens, implementat
Objective: The Attempted Suicide Short Intervention Program (ASSIP) was adapted for hospital delivery and to address substance use problems as well as evaluated for feasibility, acceptability, and therapist fidelity in a series of preparatory steps (n = 28) and in a pilot randomized controlled trial, RCT (n = 34). Method: In the RCT, patients with suicide attempts and substance use problem(s) with
The association between pesticide exposure and non-Hodgkin lymphoma (NHL) including hairy cell leukemia (HCL) was analyzed in a pooled study of three case-control studies. Results on exposure to pesticides were based on 1,425 cases and 2,157 controls participating in the studies. Exposures were assessed by self-administered questionnaires completed as needed by phone. In the pooled univariate anal
This review presents the status and outlook for shared energy systems (SES) and fifth-generation district heating and cooling (5GDHC). It provides an overview of the technical and functional knowledge encompassing design and development, operational and system architecture, and control and decision support systems of these technologies. The review also presents different tools and models found in
Dyspnea and chest pain are major and important causes of contact at the emergency department (ED). Dyspnea is associated with high morbidity and mortality, but data on characteristics and outcomes compared with chest pain in the ED are limited. This was a retrospective cohort study of consecutive patients with contact causes of dyspnea or chest pain at two Swedish EDs from 2010 to 2014. Hospital a
This article investigates a series of attempts to imbue natural history with humanistic values and align its epistemological goals with those of classical studies in Sweden during the first half of the nineteenth century. By tracing the claims made by a group of twenty-one natural scientists, physicians, and state officials as well as others who took up the cause in response to a government propos
Crop production security is an essential guarantee for the prosperity of country and the well-being of people. In the context of frequent occurrence of extreme weather events, how to comprehensively evaluate the risk of multiple hazards and quantitatively describe spatial differences will be one of the significant topics in agricultural disaster mitigation. In this study, based on the gridded mete
The subgenus Sarcophaga Meigen, 1824 (s. str.) currently comprises over 30 species distributed in the West Palearctic Region, the identification of which is normally based on characters of the male terminalia. Females of the three closely-related species Sarcophaga (Sarcophaga) carnaria (Linnaeus, 1758), S. (S.) subvicina Rohdendorf, 1937 and S. (S.) variegata (Scopoli, 1763), which are especially
