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Exploring the possibility of a systematic and generic approach to social sustainability
There is a growing need to understand how existing concepts and tools for sustainability relate to each other and to a robust, trans-disciplinary systems perspective for sustainability. As a response, a group of scientists, including some of the authors, have developed a framework based on backcasting from sustainability principles over the last 20 years the Framework for Strategic Sustainable Dev
Novel quantitative trait loci controlling collagen-induced arthritis in mice
Implementation of an economic model to simulate manufacturing costs
An economic model describing manufacturing costs is implemented within the frame of a case study. The implemented economic model is developed to enable analyses of the cost items and parameters influencing the cost of a part or a batch and also to make simulations for the purpose of investigating the economic outcome of future development activities. The aim of the case study was to identify activ
Developing m-Services; lesson learned from a developers Perspective
In recent years the Swedish Police Force (SPF) have encountered greater demands on availability and 24/7 services when dealing with errands that are regarded as low priority compared to regular police work, e.g. collecting tips from the public. One attempt to meet these increasing demands was the development of a mobile communications platform that allowed the public to communicate easily with the
Increasing constraints? Civil society organisations in Jordan vis-à-vis the state
The Jordanian state apparatus is increasingly limiting civil society in Jordan from engaging in open debate, and organisations are gradually inhibited from executing their activities and events. These are the premises on which this research is based, and in exploring them several questions arise. How can civil society in Jordan be characterised and applied? What do these obstacles look like in pra
Dröjsmålstalan och EU-rätten – En undersökning av i vad mån förvaltningslagens dröjsmålstalan uppfyller unionsrättens krav på rättsskydd
Den 1 juli 2018 trädde den nya förvaltningslagen (2017:900) i kraft. I lagen ges enskilda, genom införandet av en dröjsmålstalan, för första gången i svensk förvaltningsrätt en generell rätt att föra talan mot förvaltningsmyndigheters passivitet. Om unionsrätten inte anger annat kommer den nya dröjsmålstalan, enligt principen om medlemsstaternas processuella autonomi, att tillämpas även vid förvalOn the first of July 2018, the new Swedish Administrative Procedure Act came into force. The Act introduces a new remedy against the inaction of administrative authorities (an action for failure to act, in Swedish “dröjsmålstalan”). Through the introduction of the new remedy, individuals are given a general right to appeal against the administrative authorities' inaction for the first time in
Wilms' tumor gene 1 protein represses the expression of the tumor suppressor interferon regulatory factor 8 in human hematopoietic progenitors and in leukemic cells.
Wilms' tumor gene 1 (WT1) is a transcription factor involved in developmental processes. In adult hematopoiesis, only a small portion of early progenitor cells express WT1, whereas most leukemias show persistently high levels, suggesting an oncogenic role. We have previously characterized oncogenic BCR/ABL1 tyrosine kinase signaling pathways for increased WT1 expression. In this study, we show tha
Comparison of Self-Reported Physical Activity between Survivors of Out-of-Hospital Cardiac Arrest and Patients with Myocardial Infarction without cardiac arrest : a case-control study
AIMS: To investigate whether out-of-hospital cardiac arrest (OHCA) survivors had lower levels of self-reported physical activity compared to a non-cardiac arrest control group with myocardial infarction (MI), and to explore if symptoms of anxiety, depression, kinesiophobia (fear of movement) and fatigue were associated with a low level of physical activity.METHODS: Predefined case-control sub-studAIMS: To investigate whether out-of-hospital cardiac arrest (OHCA) survivors had lower levels of self-reported physical activity compared to a non-cardiac arrest control group with myocardial infarction (MI), and to explore if symptoms of anxiety, depression, kinesiophobia (fear of movement) and fatigue were associated with a low level of physical activity.METHODS: Predefined case-control sub-stud
Youth
Youth are one of the nine major groups of civil society for sustainable development formalized by Agenda 21. The Major Group of Children and Youth is an active independent mechanism facilitating youth involvement in the United Nations system. Youth representatives from various organizations increasingly engage in global sustainability politics but face challenges such as financial constraints, tok
Essential Concepts for Implementing the Sustainable Development Goals : An Introduction
This A-Z Guide offers an accessible and user-friendly overview of the essential concepts and terms needed to understand the implementation of the SDGs. Crafted in the form of an encyclopaedia, the volume presents 105 entries on important concepts and terms and their links to academic and policy debates. Each entry offers basic definitions of the concept or term at issue, followed by a brief discus
Cancer in first-degree relatives of women with early-onset breast cancer: a comparison of self-reported and cancer registry data
Moving on to work and feeling better-A randomised controlled trial of supported employment adapted for people with affective disorders.
Targeted Temperature Management after Cardiac Arrest. Reply
Too much too late? : Optimizing treatment through conversations over years, months, and days
Fever therapy in febrile adults : systematic review with meta-analyses and trial sequential analyses
Objective: To investigate the effects of fever therapy compared with no fever therapy in a wide population of febrile adults. Design: Systematic review with meta-analyses and trial sequential analyses of randomised clinical trials. Data sources: CENTRAL, BIOSIS, CINAHL, MEDLINE, Embase, LILACS, Scopus, and Web of Science Core Collection, searched from their inception to 2 July 2021. Eligibility cr
Prognostic implications of structural heart disease and premature ventricular contractions in recovery of exercise
Premature ventricular contractions (PVCs) during recovery of exercise stress testing are associated with increased cardiovascular mortality, but the cause remains unknown. We aimed to evaluate the association of PVCs during recovery with echocardiographic abnormalities, and their combined prognostic performance. Echocardiographic abnormalities [reduced left ventricular (LV) ejection fraction, valv
Per-Patient Illness Trajectory Analyses
Background: Summary statistics often hide individual patients' suffering, thereby impeding quality improvement efforts. Objectives: We aimed to show the experience of a population with health care toward the end of life while preserving the experience of the individual. Design: We developed a data display method called per-patient illness trajectory analysis. We tested it using a demonstration coh
The modified Medical Research Council scale misclassifies exertional breathlessness among people referred for exercise testing
BACKGROUND: Exertional breathlessness is a major symptom in cardiorespiratory disease and is often assessed using the modified Medical Research Council (mMRC) questionnaire. The mMRC might underestimate exertional breathlessness in people with impaired exercise capacity who have reduced their physical activity to avoid the symptom. We aimed to evaluate the ability of mMRC to detect abnormally high
Sharpen existing tools or get a new toolbox? Contemporary cluster initiatives and regional transformation
This paper explores the evolving landscape of regional innovation policy, focusing on the interplay between traditional cluster policies and emerging transformative agendas. Over the past decade, policy initiatives aimed at fostering place-based, collaborative innovation have proliferated. However, questions arise regarding the adequacy of existing policy tools in accommodating newer, transformati
