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Science Journals — AAAS Gustavsson et al., Sci. Adv. 10, eadk1296 (2024) 26 June 2024 S c i e n c e A d v A n c e S | R e S e A R c h A R t i c l e 1 of 20 G E N E T I C S The annotation of GBA1 has been concealed by its protein- coding pseudogene GBAP1 Emil K. Gustavsson1,2, Siddharth Sethi1,3, Yujing Gao3, Jonathan W. Brenton1,2, Sonia García- Ruiz1,4, David Zhang1, Raquel Garza5, Regina H. Reyn
SAMMANFATTNING Apply Emtunga är ett företag som saknar struktur gällande sin orderprocess. Examensarbetets syfte är därför att kartlägga företagets orderprocess samt klarlägga vilka problem som uppstår i samband med denna. Examensarbetet ämnar därmed svara på följande tre frågor: - hur orderprocessen ser ut, vilka problem som kan identifieras i samband med orderprocessen samt vilka förslag på åtg
I denna uppsats används Carol Bacchis metod “Whats the problem represented to be” för att undersöka hur problemet framställs i regeringens 34 åtgärder mot gängkriminaliteten. Denna poststrukturalistiska metod har inspirerats av Foucaults diskursanalys och grundas på premissen att vi styrs genom problemframställningar. I olika steg granskas regeringens 34-punktsprogram för att belysa den dominerand
De senaste åren har den svenska juridiken satts under press då gängkriminaliteten i landet blomstrar. Inom det svenska rättssystemet är det särskilt bevisvärderingen som har varit en aspekt som föranlett debatter om huruvida svenska domstolar gör fullgoda värderingar. Av särskilt intresse inom bevisvärderingen är de alternativför- klaringar som presenteras i rätten och därigenom inverkar på domsluIn recent years, Swedish jurisprudence has been subject to ominous pressure parallel to the flourishing of as gang crime. Within the Swedish legal system, the evaluation of evidence has been a particular aspect that has sparked debates on whether Swedish courts make adequate assessments in such cases. Particularly, the evaluation of al- ternative explanations presented in court is of specific inte
The rise of social media has brought with it new forms of civic engagement. This is a case study of the Greenpeace 2010 campaign Give the Orang-Utan a Break directed at Nestlé for its use of palm oil. The purpose of this case study is to analyse the discourse used in blogs during the Greenpeace campaign as well as to analyse the relationship be-tween different types of online content. The study ap
Syfte: Syftet är att fastställa om det finns empiriskt stöd för Bhattacharyyas (2010) ramverk genom att analysera strategiska CSR-aktiviteter. Vårt mål är att utreda om ramverket är ett lämpligt verktyg för strategiskt CSR-arbete inom organisationer. Metod: Vårt tillvägagångssätt är baserat på en kvalitativ ansats där fyra fall av CSR-aktiviteter är utvalda för en fallstudie. Teoretiska perspektivPurpose: The purpose is to determine whether there is empirical support for Bhattacharyyas (2010) framework by analyzing strategic CSR activities. Our goal is to determine whether the framework is a useful tool for strategic CSR activities. Methodology: Our approach is based on a qualitative approach where four cases of CSR activities are chosen for a case study. Theoretical perspectives: The the
Clinical pathological diagnosis and prognosis for cancer is often confounded by spatial tissue heterogeneity. This study investigates the utility of entropy as a robust quantitative metric of spatial disorder within Fourier Transform Infrared (FTIR) chemical images of breast cancer tissue. The use of entropy is grounded in its capacity to encapsulate the complexities of pixel-wise spectral intensi
Nodding syndrome is an emerging disease which have unknown transmission patterns and no properly established mechanisms for diagnosis leading to numerous hypothetical postulations. It has affected thousands of children in Uganda with debilitating effect and serious economic consequences. Spatial-temporal analysis may provide a quick mechanism to establish comparative understanding of the various h
Introduction: Vitamin D deficiency has previously been shown to be associated with cancer-related fatigue. If vitamin D deficiency affects fatigue in frail elderly has not been studied before. The aim of this study was to investigate associations between vitamin D, fatigue, frailty, and sarcopenia in frail elderly with cancer (FEC) and without cancer (FE) in comparison with healthy controls. Metho
Corrosion of cables can result in brittle and unexpected failures and represents a critical concern for prestressed concrete bridges with post-tensioned (PT) tendons. In these structures, corrosion is typically facilitated by inadequate grout injection and/or the use of poor-quality mortar during construction. Such deficiencies create favorable conditions for corrosion initiation and propagation.
Det finns inga internationella åtaganden som innebär en skyldighet för Sverige att ge parter i tvistemål tillgång till en prövning av en andra instans. Dock ska parter enligt Europakonventionen om skydd för de mänskliga rättigheterna och de grundläggande friheterna tillförsäkras en rätt till domstolsprövning och en rättssäker process. En möjlighet till överprövning av den första instansens avgöranEven though the definition of legal certainty is controversial, it may be considered generally accepted that the substantive aspect of legal certainty requires that judicial decisions are substantially right. It is also quite clear that the formal aspect of legal certainty includes a requirement of predictability concerning judicial decision making. Sweden has no enforceable international obliga
Laser thermotherapy is interesting from an immunological point of view since it can reduce tumor volume without causing immunosuppression at the same time as it may induce and/or enhance tumor immunity. In a rat liver tumor model, we have demonstrated that laser thermotherapy 1) is superior to surgical resection, 2) gives a strong rejection immunity associated with an immune cellular response of t
This study aimed to find out how the insulation of the footwear changes over one week of use. A thermal foot model with 8 measuring zones and 5 “sweat glands” was used for tests. A thin sock was donned on the model to allow better water distribution all over the foot surface. Four boots were tested over a period of 5 days. Each day was divided into 9 hour measurement period and 15 hour conditionin
Our existing urban environment has a significant potential to increase the use of renewable energy, mainly by using solar irradiation for heat and electricity. Quantification of the solar potential by means of a solar map is the first step in the acceleration process for using more solar energy in our urban environments. A solar map is a GIS system providing the annual solar irradiation on buildin
The practice of service encounters in a district court, a home for the elderly, and a hotel Service management research places the service encounter in a central position. It is highlighted as a key event that involves the simultaneous production, consumption, and marketing of the services produced by the operation. However, in this research there is a tendency to discuss the service encounter in
