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BackgroundAnti-IL-4Rα monoclonal antibodies (mAb) improve lung function and decrease the number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement of early innate immune responses underlying these treatment effects is not well known. We sought to understand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells from COPD patients under

Background and objective Breathlessness is associated with higher rates of unplanned health service utilisation. We aimed to evaluate any associations between the severity of breathlessness limiting exertion (hereafter breathlessness), time between breathlessness recording and subsequent unplanned hospital admissions, and length of stay. Methods A retrospective cohort study of adults seen in gener

För fjärde gången bjöd Odeum in till festivalen Lund Contemporary, en biennal för samtida konstmusik som arrangeras i samverkan med en rad lokala, regionala och nationella aktörer. Det blev ett varierat program där nyskriven musik varvades med samtal, tonsättarintervjuer och experimentella upplevelser. Festivalen är en plattform för nya tonspråk och kreativa idéer och ett forum för viktiga diskuss

https://www.odeum.lu.se/lund-contemporary-2023 - 2026-06-25

Microsoft Word - OtydligaMaal_V101_utankomm.doc LTHs 10:e Pedagogiska Inspirationskonferens, 6 december 2018 Sammanfattning—CEQ-resultaten för en del projektbase- rade kurser visar att studenterna upplever att kursens mål inte är tydliga (skalan ”Tydliga mål”, TM, i CEQ). Studenterna verkar således vara ganska osäkra på vad lärarna förväntar sig av dem. Detta är ett problem som kräver uppmärksamh

https://www.lth.se/fileadmin/lth/genombrottet/konferens2018/D5_Motte_etal.pdf - 2026-06-09

2017-09-25ContentsFactors which are likely to have an effect on the emergence of cancer and cardiovascular diseases, such as occupation, physical activity, tobacco and alcohol consumption, dietary habits, health, diseases in the family, use of contraceptive pills, hormonal replacement therapy etc.Lines: 22 369 (three individuals lack questionnaire data but have physical activity score)Variables: 2

https://www.malmo-kohorter.lu.se/malmo-kost-cancer-mkc/datainsamling-mkc/mdc-5-year-questionnaire - 2026-06-25

Geologiska institutionen har två avdelningar som bildar var sitt stort forskningsområde: berggrundsgeologi och kvartärgeologi. En viktig strategi är att öka samarbetet mellan dessa enheter. Nedan följer en översikt av våra åtta forskningsområden The structure of overall research themes at the Department of Geology. The two rings represent the two units Bedrock Geology and Quaternary Geology. The a

https://www.geologi.lu.se/forskning/forskningsomraden - 2026-06-25

Medlem i Strategiskt forskningsområde Kontaktinformation E-post: didac [dot] pascual [at] mgeo [dot] lu [dot] seOrganisation MERGE: ModElling the Regional and Global Earth system Hämtställe: 50 WebbplatsDidac Pascuals profil i Lunds universitets forskningsportalAndra roller Affilierad Miljö- och geovetenskapliga institutionen (MGeo) Medlem i Strategiskt forskningsområde BECC: Biodiversity and Ecos

https://www.nateko.lu.se/sv/didac-pascual - 2026-06-25

A debate in the EU and Sweden is ongoing on whether advertising of fossil fuels is to be banned. Some state that banning fossil fuel advertising is one step in the right direction toward a more sustainable world. In contrast, others say that the prohibition of communication channels prevents consumers from intake transparent communication, especially in a democratic country. This study problematiz

AIM: To compare 14 and 24 weeks treatment to patients with HCV genotype 2 or 3 infection and rapid virological response (RVR). MATERIALS AND METHODS: Patients included in two Scandinavian trials, one nonrandomized pilot trial (n=122) and one randomized controlled trial (RCT) (n=428) were entered into a pooled database. In both trials treatment naïve patients with genotype 2 or 3 were treated with

BACKGROUND: Vascular endothelial dysfunction, accelerated thickening of arterial intima, and changes in ventricular repolarization contribute to increased cardiovascular morbidity in type 1 diabetes (T1D). Although vitamin C has important antioxidant functions and increased oxidative stress is a central mechanism of cardiovascular dysfunction in T1D, the relation between vitamin C and the cardiova

Influenza A virus encodes two segments (7 and 8) that produce mRNAs that can be spliced. We have investigated if naturally occurring sequence polymorphisms in the influenza A virus family affects splicing of these viral mRNAs, as that could potentially alter the NS1/NS2- and/or M1/M2-protein ratios. We compared splicing efficiency of segment 7 and 8 mRNAs of A/Brevig Mission/1918/1 (H1N1) and A/Ne

Familial clustering of prostate, breast and colorectal cancer is well established, but the familial risk of these cancers has not been determined among adoptees. The aim was to disentangle the contributions of genetic and environmental factors to the familial transmission of prostate, breast and colorectal cancer.

Long-chain n-6 and n-3 PUFA (LC-PUFA), arachidonic acid (AA) (20:4n-6) and DHA (22:6n-3), are critical for optimal brain development. These fatty acids can be consumed directly from the diet, or synthesized endogenously from precursor PUFA by Δ-5 (encoded by FADS1) and Δ-6 desaturases (encoded by FADS2). The aim of this study was to determine the potential importance of maternal genetic variabilit

In a previously published study, vildagliptin showed a reduced risk of hypoglycemia versus glimepiride as add-on therapy to metformin at similar efficacy. Glimepiride was titrated from a starting dose of 2 mg/day to a maximum dose of 6 mg/day. It is usually assumed that the increased hypoglycemia with glimepiride was driven by the 6 mg/day dose; it was therefore of interest to assess whether the r

The absence of compassion, argues the author, is not the cause of healthcare failures but rather a symptom of deeper systemic failures. The clinical encounter arouses strong emotions of anxiety, fear, and anger in patients which are often projected onto the clinicians. Attempts to protect clinicians through various bureaucratic devices and depersonalization of the patient, constitute as Menzies no

Background: Extracellular-signal regulated kinase (ERK1/2) is activated by nerve damage and its activation precedes survival and proliferation of Schwann cells. In contrast, activation of caspase 3, a cysteine protease, is considered as a marker for apoptosis in Schwann cells. In the present study, axonal outgrowth, activation of ERK1/2 by phosphorylation (p-ERK 1/2) and immunoreactivity of cleave