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Popular Abstract in Swedish Anhöriga – aspekter på börda, livstillfredsställelse och effekter av stöd. Med en ökande befolkning av äldre och en samtidig minskning av möjligheter till hjälpinsatser inom såväl kommunalt som landstingsstyrd vård och omsorg, kommer många av oss ta hand om äldre familjemedlemmar, släktingar och vänner. Hur kommer detta att påverka oss? Ungefär 20 % av den vuxna befol
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Background Exertional breathlessness is a key symptom in cardiorespiratory disease and can be quantified using incremental exercise testing, but its prognostic significance is unknown. We evaluated the ability of abnormally high breathlessness intensity during incremental cycle exercise testing to predict all-cause, respiratory, and cardiac mortality. Study design and methods Longitudinal cohort s
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Deaths of despair (DoD), encompassing suicide, drug overdose, and alcohol-related mortality, are often linked to social and psychological distress. This study examined the long-term risk of DoD among individuals previously hospitalized for suicide attempts, with a focus on substance use problems and psychiatric disorders as potential risk factors. A prospective cohort of 1044 individuals admitted
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Wireless access technologies such as UMTS with HSPA extensions, WiMAX, and Flash-OFDM and the convergence towards next generation heterogeneous networks enable the realization of always best connected scenarios. As the resulting heterogeneous networks become easier to access and more reliable to depend on, novel telemedicine services such as vehicular emergency applications emerge. Due to their li
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Most state-of-the-art natural gas-fired combined cycle (NGCC) plants are triple-pressure reheat cycles with efficiencies close to 60%. However, with carbon capture and storage, the efficiency will be penalized by almost 10% units. To limit the energy consumption for a carbon capture NGCC plant, exhaust gas recirculation (EGR) is necessary. Utilizing EGR increases the CO2 content in the gas turbine
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Popular Abstract in Swedish Tre-dimensionell ultraljudsundersökning av livmodertappen (cervix) Syftet med avhandlingen var att utvärdera förändringar i livmodertappen (cervix) med tre-dimensionellt ultraljud och utreda om tre-dimensionellt power Doppler ultraljud kan förutsäga tiden till spontan eller inducerad förlossning hos överburna, gravida kvinnor. Avhandlingen baseras på fem studier: reprThe aim of this thesis was to evaluate cervical physiological changes by three-dimensional (3D) ultrasound during pregnancy and to investigate the ability of 3D power Doppler to predict time to spontaneous and induced delivery in prolonged pregnancy. The thesis is based on five studies: reproducibility of cervical measurements by 3D power Doppler ultrasound (study I), reference data representativ
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Parkinson's disease (PD) is a neurodegenerative disease with unknown etiology. Here we show the generation of an induced pluripotent stem cell (iPSC) line, named CSC-40, from dermal fibroblasts obtained from a 59-year-old male patient with a homozygous p.Q456X mutation in the PTEN-induced putative kinase 1 (PINK/PARK6) gene and a confirmed diagnosis of PD, which could be used to model familial PD.
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Al2O3 and HfO2 high-k oxides deposited by atomic layer deposition have been studied on InAs 100 and 111B surfaces. By using a low-frequency fitting routine, interface defect densities have been extracted. In general, both HfO2 and Al2O3 show similar D-it profiles, with a D-it minimum around 2x10(12) eV(-1)cm(-2).
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OBJECTIVES: To evaluate knowledge translation after publication of the target temperature management 33°C versus 36°C after out-of-hospital cardiac arrest trial and associated patient outcomes. Our primary hypothesis was that target temperature management at 36°C was rapidly adopted in Australian and New Zealand ICUs. Secondary hypotheses were that temporal reductions in mortality would be seen an
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The extent to which in-situ global mechanical tensioning (GMT) can be used to modify the residual stress state in friction stir (FS) welds is investigated in this article. Residual stress distributions have been determined by synchrotron X-ray and neutron diffraction for four sets of FS welds in high-strength AA7449-W51 and lithium containing AA2199-T8 aerospace aluminum alloys subjected to a syst
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Delamination plays a pivotal role during normal development and cancer. Previous work has demonstrated that delamination and epithelial cell movement within the plane of an epithelium are associated with a change in cellular phenotype. However, how this positional change is linked to differentiation remains unknown. Using the developing mouse pancreas as a model system, we show that β cell delamin
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This discussion paper recognizes that the Glasgow Consensus Statement is not optimally useful unless it is disseminated widely. Knowledge and use of the consensus statement and its call for centering humanism in healthcare extend to medical and health organizations and groups beyond the International Conference on Communication in Healthcare and Patient Education and Counseling audiences, to profe
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Denna berättelse om Synergi mellan Strål- och Immun-Terapi har sitt ursprung i resultaten av försök som utfördes år 2001 vilka avsåg att kombinera tumörvaccin-behandling med strålterapi av Fischer-344 råttor med gliom-tumörer inokulerade i hjärnan.Med 3 omgångar tumörvaccin kombinerat med endast en fraktion strålterapi á 5Gy, överlevde sex av åtta behandlade djur (ca.75%). Detta dramatiska re
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Background: Exertional breathlessness is a cardinal symptom of people with chronic airflow limitation (CAL) and can be evaluated using cardiopulmonary exercise testing (CPET). Research Question: Does abnormally high exertional breathlessness in relationship to the rate of oxygen uptake (V′O2) and minute ventilation (V′E) indicate different underlying pathophysiologic mechanisms and clinical charac
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Background: Treatment of common bile duct (CBD) stones after Roux-en-Y gastric bypass (RYGB) poses a particular challenge given the altered anatomy and inability to perform a standard endoscopic retrograde cholangiogram (ERC). The optimal treatment strategy for intraoperatively encountered CBD stones in post-RYGB patients has not been established. Objectives: To compare outcomes following laparosc
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Ten per cent of patients with colorectal cancer will develop peritoneal metastases. These metastases are known to have a lesser response to systemic chemotherapy than liver- and lung metastases. Randomized studies have shown that adding cytoreductive surgery and heated intraperitoneal chemotherapy (HIPEC) to this treatment gives a better chance of survival. Recently, a randomized study failed to s
