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Background: Rat pups are born with an immature intestine adapted for the effective uptake of milk nutrients and with high permeability for bioactive molecules from the maternal milk until weaning. During weaning the immune system is activated after stimulation with e.g. dietary antigens, leading to an inflammatory response in the gut. This response is believed to be important for progress of gut m
Introduction Neoadjuvant therapy is the standard of care for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC). Studies on first-generation antibody-drug conjugates, such as trastuzumab emtansine (T-DM1), showed equal or slightly lower efficacy than chemotherapy combined with dual HER2 blockade. Trastuzumab deruxtecan (T-DXd) is a next-generation conjugat
Background: For patients investigated with radiopharmaceuticals, it is important to be able to perform valid calculations of the absorbed dose in organs and tissues. An internal dosimetry computer program, IDAC-Dose2.1, has been updated to be based on the ICRP specific absorbed fractions and computational framework of internal dose assessment for 12 adult and paediatric reference individuals given
According to the economy theory, plants should preferentially allocate photosynthate to acquire below-ground resources under elevated atmospheric carbon dioxide (eCO2) but decrease below-ground C allocation when nitrogen (N) is sufficient for plant growth. Arbuscular mycorrhizae (AM) represent a critical mechanism of below-ground nutrient acquisition for plants. The dynamics of arbuscular mycorrhi
Accurate monitoring of glaciers’ extents and their dynamics is essential for improving our understanding of the impacts of climate and environmental changes in cold regions. The satellite-based Normalized Difference Snow Index (NDSI) has been widely used for mapping snow cover and glaciers around the globe. However, mapping glaciers in snow-covered areas using existing indices remains a challengin
Articular cartilage and meniscus transfer and distribute mechanical loads in the knee joint. Degeneration of these connective tissues occurs during the progression of knee osteoarthritis, which affects their composition, microstructure, and mechanical properties. A deeper understanding of disease progression can be obtained by studying them simultaneously. Time-resolved synchrotron-based X-ray pha
Using Euryale ferox husk as raw material, pristine biochar (EBC), Bi2MoO6-modified biochar (BM-EBC), and BiFeO3-modified biochar (BF-EBC) were prepared and employed for decontaminating Congo red (CR) from wastewater. Compared with EBC (217.59 mg/g) and BF-EBC (359.49 mg/g), a superior adsorption capacity of 460.77 mg/g was achieved by BM-EBC. Based on the evaluation results of the Freundlich and p
Background In addition to the diagnostic accuracy of imaging methods, patient-reported satisfaction with imaging methods is important. Objective To report a secondary outcome of the prospective international multicenter Imaging Study in Advanced ovArian Cancer (ISAAC Study), detailing patients’ experience with abdomino-pelvic ultrasound, whole-body contrast-enhanced computed tomography (CT), and w
Background: Electrocardiographic detection of patients with occlusion myocardial infarction (OMI) can be difficult in patients with left bundle branch block (LBBB) or ventricular paced rhythm (VPR) and several ECG criteria for the detection of OMI in LBBB/VPR exist. Most recently, the Barcelona criteria, which includes concordant ST deviation and discordant ST deviation in leads with low R/S ampli
Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by tau and amyloid brain pathology. With the gradual degeneration of neurons, cognitive symptoms will arise and the affected individual will eventually develop AD dementia. The neuropathologic hallmarks of AD have been observed also in cognitively healthy individuals, which has led to the assumption that the disorde
Abstract Author: Emily Andersson and Nathalie Lantz Title: The traumatised children – a study about how children suffering from Post Traumatic Stress Disorder are being received and treated [translated title]. Supervisor: Gunilla Lindén Examiner: Åsa Lundqvist The purpose of this study was to enter deeply into the treatment of children with Post Traumatic Stress Disorder. More specifically the ai
The recycling sector and the solid waste management systems (SWMS) in developing countries greatly rely on scavengers, a vulnerable and marginal urban population that recover items or materials to be reused or recycled. As a new mindset towards waste emerges, considering it a resource instead of something useless and undesirable; governments, NGOs, private companies and other stakeholders slowly r
In the wake of the globalization, international tax planning structures has become vital for US investors in order to meet economic challenges and to survive on the competitive market. This research indicates that countries in Europe, such as Sweden and Switzerland, provide a favourable environment for US multinational corporations to set up holding companies as a way to enjoy benefits of legal ta
The thesis explores how the political discourse on refugees and asylum seekers is produced within portfolio committee meetings at the South African parliament. A critical discourse analysis investigates how statements of delegates of the Department of Home Affairs and Social Development foster unequal power relations and construct social identities perpetuating the on-going discourse on refugees a
The concept of experimentation is increasingly promoted to facilitate social learning for sustainability transitions. Experiments are collaborative initiatives designed to generate knowledge and test innovative practices to address a collective sustainability challenge. However, it is often unclear whether experiments generate any impact beyond the initial project scope. Recent literature has call
In 2000, the Clinton Administration in the U.S. adopted the Commodity Futures Modernization Act, which deregulated the U.S. trade with financial instruments on commodity markets. With respect to this adoption, it has been regarded as one catalyst for the Global food crisis 2008, where millions of individuals lacked provision and access to agricultural products and nutrition. From the perspective o
The intake of anthocyanin rich-foods, such as bilberries has been associated with a reduced risk of developing cardiovascular-related diseases. Similarly, the cardiovascular benefits of oat consumption are well known and are mainly due to its cholesterol-lowering and hypoglycemic effects. A randomized double-blinding clinical trial has been designed to investigate the cardiovascular beneficial eff
Hittills har över 50 miljoner ton e-avfall genererats globalt (World Economic Forum, 2019), vilket väcker frågan om den cirkulära ekonomins roll i kampen mot klimatförändringarna (Ellen MacArthur Foundation, 2021). I detta examensarbete undersöks möjligheterna för Axis Communications att införa ett system i USA för att ta tillbaka produkter som tagits ur bruk och återvinna dem. Inom detta område So far, over 50 million tonnes of e-waste have been generated globally (World Economic Forum, 2019), raising the question of the role of circular economy in combating climate change (Ellen MacArthur Foundation, 2021). This thesis explores the opportunities for Axis Communications to introduce a take back system for recycling decommissioned products in the US. Within this scope, several areas are
