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The advent of optogenetic tools has had a profound impact on modern neuroscience research, revolutionizing our understanding of the brain. These tools offer a remarkable ability to precisely manipulate specific groups of neurons with an unprecedented level of temporal precision, on the order of milliseconds. This breakthrough has significantly advanced our knowledge of various physiological and pa
PURPOSE: The local immune infiltrate's influence on tumor progression may be closely linked to tumor-intrinsic factors. The study aimed to investigate whether integrating immunologic and tumor-intrinsic factors can identify patients from a low-risk cohort who may be candidates for radiotherapy (RT) de-escalation.EXPERIMENTAL DESIGN: The SweBCG91RT trial included 1,178 patients with stage I to IIA
The lung may be the organ whose mechanical environment needs to be most finely tuned to achieve optimal function. These needs have to be fulfilled at multiple scales, from proper force transmission between the chest wall and the parenchyma to reduction of surface tension by surfactants inside the alveoli. In addition, a plethora of mechanical loads and forces takes place within the lung, from the
Primary prevention of type 1 diabetes (T1D) requires intervention in genetically at-risk infants. The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) has established a screening program, GPPAD-02, that identifies infants with a genetic high risk of T1D, enrolls these into primary prevention trials, and follows the children for beta-cell autoantibodies and diabetes. Genetic testin
Den främsta orsaken till en ökad växthuseffekt anses idag bero på en högre koncentrationav koldioxid i atmosfären. Sedan den industriella revolutionen harmänniskan påverkat mängden koldioxid i atmosfären genom aktiviteter så somförbränning av fossila bränslen, avskogning, förändringar i markanvändning, samtcementproduktion. För att kunna motverka framtida klimatförändringar krävs enfördjupad kunskThis thesis focuses on the development and application of efficient mathematicaltools for estimating and modelling the exchange of carbon dioxide (CO2) between the Earth and its atmosphere; here referred to as the global CO2 surface flux.There are two main approaches for estimating the CO2 flux: Processed based(bottom-up) modelling and atmospheric inversion (top-down) modelling. Thefirst part of t
BACKGROUND: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is the preferred treatment of peritoneal carcinomatosis (PC) of colorectal carcinoma. Patients with positive lymph node status have worse survival after CRS-HIPEC, which is probably due to higher rates of systemic failure. In this study, we analysed the effect of administration and timing of systemic chemot
The market for ready-to eat vegetables is increasing, but unfortunately so do the numbers of food-borne illness outbreaks related to these products. A previous study has identified bacterial strains suitable for biocontrol of leafy green vegetables to reduce the exposure to pathogens in these products. As a tentative safety evaluation, five selected strains (Rhodococcus cerastii MR5x, Bacillus coa
Context: There is a dispute whether obesity without major metabolic derangements may represent a benign condition or not. Objective: We aimed to compare the plasma metabolome in obese subjects without metabolic syndrome (MetS) with normal-weight subjects without MetS and with obese subjects with MetS. Methods: This was a cross-sectional study at 2 academic centers in Sweden. Individuals from 3 pop
Background A clustering of cardiovascular risk factors is denoted the metabolic syndrome (MetS), but the mechanistic underpinnings of this clustering is not clear. Using large-scale metabolomics, we aimed to find a metabolic profile common for all five components of MetS. Methods and findings 791 annotated non-xenobiotic metabolites were measured by ultra-performance liquid chromatography tandem m
The subtitle of this essay echoes the title of David E. James’s book The Most Typical Avant-Garde, which makes the claim that the various minor cinemas of Los Angeles (amateur, immigrant, artists’ etc.) constitute the most distinctive avant-garde “on behalf of cultural practices that are commonly supposed not to even have existed”. The heterogeneous Swedish avant-garde scene has definitely been co
Introduction It is standard of care to provide sedation to critically ill patients to reduce anxiety, discomfort and promote tolerance of mechanical ventilation. Given that sedatives can have differing effects based on a variety of patient and pharmacological characteristics, treatment approaches are largely based on targeting the level of sedation. The benefits of differing levels of sedation mus
BackgroundMale involvement in maternal health care has proven to be beneficial for improving maternal and child health and is often crucial in areas of family planning and contraceptive use. However, compared to male involvement in maternal health care, male involvement in contraceptive counselling is complex and controversial and thus faces certain challenges. Immigrant men in Sweden are often ac
Background: Impaired quadriceps muscle strength after anterior cruciate ligament reconstruction (ACLR) is associated with worse clinical outcomes and a risk of reinjuries. Yet, we know little about quadriceps muscle strength in patients reconstructed with a quadriceps tendon (QT) graft, which is increasing in popularity worldwide. Purpose: To describe and compare isokinetic quadriceps strength in
This thesis studies how subject extractions are accepted in Scandinavian (Danish, Norwegian, Swedish and Fenno-Swedish) through an extensive acceptability judgment study. The results from the study were compared with previous research and analyzed against accounts on why subject extraction constraints occur and why the acceptance of subject extractions in Scandinavian vasty varies. The subject ext
Title: Mapping the usage of returnable packaging material and a proposal for improvements - a Case Study at Haldex AB in Landskrona Author: Annika Jönsson Supervisor: Enes Hasic & Anders Pålsson, Haldex AB, Landskrona Eva Berg, Department of Industrial Management and Logistics, Division of Engineering Logistics, Faculty of Engineering, Lund University Examiner: Jan Olhager, Department of Indus
This essay investigates the need for prioritizing resilience and mindfulness in academia and elaborated on a pragmatic approach to how we as scholars can improve our well-being collectively in today’s demanding academic environment.
The aim of the creation of this cohort was to investigate patterns of health and health care utilisation before and during the COVID-19 pandemic, overall and in relation to specific diagnoses, among people with intellectual disabilities (ID) compared to the general population. People living in Skåne, the southernmost region of Sweden, on 1st of January 2014 with at least one diagnosis of ID (ICD-1
Jason Erwin Realizing Malmö’s Neighborhood Functionality and Social Capital Potential The Impacts of High-Speed Transport Infrastructure on Rosengård and Fosie Abstract: Increasingly, urban and suburban areas in many western cities are shaped by the tides of high-speed flows of people and goods. While an integral piece of our socio-economic fabric high-speed transport infrastructure (HSTI), limite
https://www.lumes.lu.se/sites/lumes.lu.se/files/erwin_jason.pdf - 2026-07-25
SASI03: Environmental Studies and Sustainability Science: Concepts, Challenges and Approaches in Sustainability Studies Study guide 7.5 credits Spring 2018: 15th January- 19th March Schedule Day Date Time Venue Title Teacher Week 1 Mon 15/1 10-12 Wrangel Library Roll-call & course introduction Mandatory Stephen Woroniecki Wed 17/1 13-15 Carson Key concepts, debates and history of Environmental and
https://www.lumes.lu.se/sites/lumes.lu.se/files/sasi03_study_guide_update_140218.pdf - 2026-07-25
Adato användarmanual Sida 0. Miljödata AB Ronnebygatan 46 0455 – 33 35 30 BG: 5504-4325 Org. nr: 556324-4036 371 33 Karlskrona miljodata.se Författare: Tova Westin PG: 17141-3 Adato användarmanual Version 3.7.3 Senast uppdaterad: 2025-12-03 Adato användarmanual Sida 1. Miljödata AB Ronnebygatan 46 0455 – 33 35 30 BG: 5504-4325 Org. nr: 556324-4036 371 33 Karlskrona miljodata.se Författare: Tova We
https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2026-02/Adato%203.7.3%20anv%C3%A4ndarmanual%20(1).pdf - 2026-07-25
