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Occupational exposure to diisocyanates within the plastic industry causes irritation and disorders in the airway. The aim of this study was to develop, validate and characterize a method for the determination of 2,4-toluenediamine (2,4-TDA), 2,6-toluenediamine (2,6-TDA), 1,5-diaminonaphthalene (1,5-NDA) and 4,4'-methylenedianiline (4,4'-MDA) in hydrolysed urine and plasma, and to study the correla
BACKGROUND: Summary measures of health are essential in making estimates of health status that are comparable across time and place. They can be used for assessing the performance of health systems, informing effective policy making, and monitoring the progress of nations toward achievement of sustainable development goals. The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD
Background: Throughout the world many people have both obesity and chronic pain, comorbidities that decrease Health-Related Quality of Life (HRQoL). It is uncertain whether patients with comorbid obesity can maintain improved HRQoL after Interdisciplinary Multimodal Pain Rehabilitation (IMMPR). Methods: Data from 2016, 2017, and 2018 were obtained from a national pain database for Swedish speciali
Researchers and teachers often recommend motivating exercises and use of mathematics or statistics software for the teaching of basic courses in probability and statistics. Our courses are given to large groups of engineering students at Lund Institute of Technology. We found that the mere existence of real-life data and technology in a course does not automatically increase students’ motivation o
This master’s thesis explores everyday life on the islands Asperö and Brännö, located in the South archipelago of Gothenburg. Although the islands are part of the Gothenburg municipality, their geographical separation creates unique, place-specific challenges, while also the boundedness of the islands' isolation fosters a sense of community among residents. The aim of the study is to gain an u
Detrital zircon age and Hf isotope patterns for the Cahill Formation and Nourlangie Schist are distinctly different from other Paleoproterozoic successions in the North Australian Craton. The Cahill Formation and Nourlangie Schist comprise the bulk of the Paleoproterozoic strata in the Nimbuwah Domain, the easternmost part of the Pine Creek Orogen on the northern margin of the North Australian Cra
During the last few years, recombinant viral vectors derived from adenovirus (Ad), adeno-associated virus (AAV) or lentivirus (LV) have been developed into highly effective vehicles for gene transfer to the adult central nervous system. In recent experiments, in the rat model of Parkinson's disease, all three vector systems have been shown to be effective for long-term delivery of glial cell line-
The neuropeptide Y (NPY) family of peptides and receptors regulate food intake. Inherited variation in this pathway could influence susceptibility to obesity and its complications, including type 2 diabetes. We genotyped a set of 71 single nucleotide polymorphisms (SNPs) that capture the most common variation in NPY, PPY, PYY, NPY1R, NPY2R, and NPY5R in 2,800 individuals of recent European ancestr
The elderly population is increasing and with advanced age comes a higher risk for contracting diseases and excessive medicine use. Polypharmacy can lead to drug-related problems and an increased need of health care. More needs to be done to help overcome these problems. In order for new models to be successful and possible to implement in health care they have to be accepted by caregivers. The ai
Problem and Urgency: A global loss of cultivated biodiversity and traditional knowledge and practices can be observed. It is, however, essential to preserve this heritage that contributes to climate resilience, diversification of ecosystems and the dynamization of rural areas. Approach: Based on the work with Connecta Natura in the Sierra de Espadán (Spain), this thesis makes a proposal for a netw
The Yaw Power Backup System (YPBS) is a safety system that needs to be incorporated in the Wind Power Plant (WPP) in order to provide emergency power during a power outage. The YPBS enables the Wind Turbine Generator (WTG) to perform a yawing operation in extreme weather conditions. The yawing operation ensures the rotor is aligned with incoming wind, minimizing the acting forces on the blades and
In the last decades, the role of warehouses has increased due to wider product range, emphasis on shorter lead times and constant changes in customer demand. The increased demands forces companies to improve their warehousing operations for better service level and decreased costs. Different technology solutions like WMS and RFID are currently available for supporting this improvement. However, th
Syftet med denna uppsats är att granska det rättsliga skyddet för visselblåsare i Sverige. Syftet är även att utreda om eventuella problem som finns med detta skydd löses genom de lagförslag som finns i de offentliga utredningarna SOU 2013:79 och SOU 2014:31. Det finns inte någon lagstiftning i Sverige som specifikt inriktar sig på skydd för visselblåsare. Det rättsliga skyddet är komplext och berThe purpose of this paper is to examine the legal protection of whistleblowers in Sweden. The purpose is also to examine if any problems with this legal protection are solved by the bills in two Government Official Reports – SOU 2013:79 and SOU 2014:31. There is no specific regulation in Swedish law for the protection of whistleblowers. The legal protection is complex and different rules from diff
Background: Every year, many infants are infected with the respiratory syncytial virus (RSV) or other agents and need hospitalisation due to bronchiolitis. The disease causes much suffering and high costs. Thus, it is important that the treatment methods are both effective and cost-efficient. The use of different physiotherapy treatment methods is debated, and not all methods are evaluated scienti
Large igneous provinces (LIPs) and especially their dyke swarms are pivotal to reconstruction of ancient supercontinents. The Dharwar craton of southern Peninsular India represents a substantial portion of Archean crust and has been considered to be a principal constituent of Superia, Sclavia, Nuna/Columbia and Rodinia supercontinents. The craton is intruded by numerous regional-scale mafic dyke s
Background: Little is known about the long-term effectiveness of behavioural therapy for tics. We aimed to assess the long-term clinical and cost-effectiveness of online therapist-supported exposure and response prevention (ERP) therapy for tics 12 and 18 months after treatment initiation. Methods: ORBIT (online remote behavioural intervention for tics) was a two-arm (1:1 ratio), superiority, sing
PURPOSE: Radiation to the bone and exposure to alkylating agents increases the risk of bone cancer among survivors of childhood cancer, but there is uncertainty regarding the risks of bone tissue radiation doses below 10 Gy and the dose-response relationship for specific types of chemotherapy.METHODS: Twelve European countries contributed 228 cases and 228 matched controls to a nested case-control
Disaster-induced and conflict-induced forced displacements areamong the biggest humanitarian and development challenges of the countriesaround the world in the 21st century. The increasing rate of the forced displacementputs significant pressure on the built environment which popularly includes thechallenges associated with delivering the essential goods and services, providingadequate and appropr
Background: Opioid substitution treatment (OST) populations are aging and have increased mortality and somatic morbidity compared to general populations internationally. While OST patients have poor self-rated physical health and unmet healthcare needs, documented healthcare utilization has been sparsely investigated. The aim of this study was to assess registered healthcare utilization for somati
