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OBJECTIVE: To develop a new chronic RA model which is driven by the innate immune system.METHOD: The injection of a cocktail of four monoclonal antibodies against collagen type II followed by intra-peritoneal injections of mannan (from Saccharomyces cerevisiae) on days 5 and 60 led to the development of chronic arthritis in B10.Q mice. The role of the innate versus the adaptive immune system in th

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The purpose of this thesis is to augment our understanding of the Church of Yimrhane Kristos, and the Lasta period in which it was built, from the study of a variety of source materials. Due to the fact that the Lasta period suffers from the absence of adequate and reliable literary sources, this study largely depends on the elements of historic buildings as the basic data source. Using archaeomet

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In the last century, starch present in foods was considered to be completely digested. However, during the 1980s, studies on starch digestion started to show that besides digestible starch, which could be rapidly ors lowly hydrolysed, there was a variable fraction that resisted hydrolysis by digestive enzymes. That fraction was named resistant starch (RS )and it encompasses those forms of starch t

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The light-dependent magnetic compass of birds provides orientation information about the spatial alignment of the geomagnetic field. It is proposed to be located in the avian retina, and be mediated by a light-induced, biochemical radical-pair mechanism involving cryptochromes as putative receptor molecules. At the same time, cryptochromes are known for their role in the negative feedback loop in

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There is an extensive research that explores the reproduction of transnational communities and relations, with a particular focus on locality, identity and culture. However, the existing literature on transnational migration is largely based on the case studies of immigrant communities living in the United States and Western Europe, while not much has been said about the transnational practices of

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University incubators are an opportunity to promote the dissemination of research, change teaching practices and contribute to territorial economic development. In this article we present a structural and dynamic analysis of such an innovation system of a Swedish eco-innovation system by proposing elements for analysing the success of such innovation systems.

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Global warming and an increasing population needing more buildings are important issues ahead. Hence, Net ZEBs and green buildings is one of many necessary measures for climate change mitigation. Some studies indicate that improved energy and/or green performance in these buildings may not be profitable. However, a short time perspective and narrow concept for evaluation may be wrong. This study p

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We propose a technique to generate non-projective word orders in an efficient statistical linearization system. Our approach predicts liftings of edges in an unordered syntactic tree by means of a classifier, and uses a projective algorithm for tree linearization. We obtain statistically significant improvements on six typologically different languages: English, German, Dutch, Danish, Hungarian, a

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Some lactic acid bacteria, especially Lactobacillus spp., possess adhesive properties enabling colonization of the human gastrointestinal tract. Two probiotic Lactobacillus plantarum strains, WCSF1 and 299v, display highly different mannose-specific adhesion, with L. plantarum 299v being superior to L. plantarum WCFS1 based on a yeast agglutination assay. A straightforward correlation between the

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Background: B-cells are essential in immunity against malaria, but which sub-sets of B-cells specifically recognize Plasmodium falciparum and when they appear is still largely unknown. Results: Using the flow cytometry technique for detection of P. falciparum specific (Pf+) B-cells, this study for the first time measured the development of Pf+ B cell (CD19+) phenotypes in Ugandan babies from birth

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We extend a thermodynamically consistent finite strain micro-sphere framework elaborated by Carol et al. towards the modelling of phase-transformations to allow for the simulation of polycrystalline solids such as, e.g., shape memory alloys and shape memory polymers undergoing large deformations. The considered phase-transformation mechanism is based on statistical physics and allows the considera

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Only in Sweden, single-family houses account for approximately 30% of energy use in all buildings and a large part uses only electricity for heating. The potential for improvements on energy efficiency in these houses is large. This study theoretically investigates retrofitting of electrically heated Swedish single-family houses by using an air-source heat pump for both space heating and domestic

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This article sketches a transdisciplinary theoretical framework for understanding the so-called Anthropocene in terms of global inequalities. The concept of the Anthropocene has several profound implications that challenge central aspects of the modern worldview. Its relation to issues of global justice requires a cataclysmic reconceptualization of conventional notions of development, economic gro

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Background: A complexity of factors determines outcome of foot ulcer infections in diabetic subjects. Variations in patient characteristics, treatment strategies and differences in health care systems may influence outcome. Objective: To evaluate the homogeneity in patients with diabetic foot ulcer infections of sufficient severity to warrant antibiotic treatment in three different European foot c

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Stars in open clusters are expected to share an identical abundance pattern. Establishing the level of chemical homogeneity in a given open cluster deserves further study as it is the basis of the concept of chemical tagging to unravel the history of theMilkyWay.M67 is particularly interesting given its solar metallicity and age as well as being a dense cluster environment.We conducted a strictly

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BACKGROUND: Aggregate and risk-stratified perioperative mortality rates (POMR) are well-documented in high-income countries where surgical databases are common. In many low-income and middle-income country (LMIC) settings, such data are unavailable, compromising efforts to understand and improve surgical outcomes. We undertook a systematic review to determine how POMR is used and defined in LMICs

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Reality isn’t what it appears to be. Contexts are not always clear and visible. People don’t always say what they really mean. And they don’t always mean what they say. When life is your stage manager, anything can happen. I often say, life is hard, my head is harder. Making documentaries is not for the faint-hearted.This PhD project explores creative processes and parallel realities in documentar