Filtyp
Research has been performed model the dynamics of different kinds of wastewater treatment systems. Plant models are built up from standard modules of subprocesses. Available model knowledge has been packaged into suitable software modules and a library of simulation models has been created. The paper describes this library and the kind of simulations that can be performed.
A computer simulated microworld was used to study risk management in a critical infrastructure context. 36 students assumed the role of an electric distribution company Chief Executive Officer (CEO) making decision on how to spend resources between investments in risk reduction and other investments. We studied the effect of differences in terms of the incentives to invest in risk reduction and th
Performing risk assessments for hierarchical, multi-functional systems, such as a municipality, is an activity that requires input from a multitude of actors. In such systems risk assessments can be performed at many system levels and support different types of decisions. For issues that are constrained to a specific sub-system, such as a municipal department, decisions can be preferably taken at
This article deals with an essential problem in the metal cutting industry, the problem of predicting tool wear and tool life. This is also a problem that has been studied by academia for the last century, often with very little added knowledge. The possibility to replace a large number of systematic wear tests with only a few specially designed
4-Quinolones affect mammalian cellular functions in vitro in several ways. Inhibition of cell proliferation differ widely among 4-quinolones. Ciprofloxacin is one of the most antiproliferative inhibiting cell growth with about 30% at 20 mg/l. Genotoxocity tests with 4-quinolones are probably 'false' positive due to an increased [3H]-thymidine uptake not related to DNA damage. Ciprofloxacin at 10 m
This paper demonstrates the potential of asymmetrical flow field flow fractionation coupled with online multi-angle light scattering, differential refractive index and UV detection for the fractionation and analysis of macromolecules in beer regarding their composition, molar mass (M) and relative concentration. The macromolecules in the liquid and foam of two types of beer, light lager and porter
We used in vivo amperometry to monitor changes in synaptic dopamine (DA) release in the striatum induced by overexpression of human wild-type α-synuclein in nigral DA neurons, induced by injection of an adeno-associated virus type 6 (AAV6)-α-synuclein vector unilaterally into the substantia nigra in adult rats. Impairments in DA release evolved in parallel with the development of degenerative chan
OBJECTIVE: To compare the differences in standing balance and gait performance between two populations, correlated with age and physical activities of daily living. DESIGN: A cross-sectional study. SETTINGS: Malmo, the third largest city in Sweden, and Sjobo, a typical agricultural community 60 km east of Malmo. PARTICIPANTS: Participants were 570 men and women from the urban community (urban) and
Pattern recognition is an integral part of the innate immune system. The human contact system has been shown to interact with the surface of many bacterial and fungal pathogens, and once activated leads to the generation of antimicrobial peptides and the proinflammatory mediator bradykinin. Here we show that apart from these surfaces also neutrophil extracellular traps (NETs) provide a surface tha
In adult mice, the VpreB genes are expressed in bone marrow progenitor (pro-) and precursor (pre-) B cells. As part of the pre-B cell receptor, the proteins are crucial for the proliferation of these cells and consequently normal B lymphocyte development. Using cell lines, we identified a lineage- and developmental-stage-specific VpreB1 enhancer. Here, we analyze its specificity in vivo by generat
Context: Dopamine agonists are the treatment of choice for prolactinomas and symptomatic idiopathic hyperprolactinemia. However, the optimal treatment strategy and treatment duration is not clear in all details. Objective: The aim of the study was to assess the effect of dopamine agonist withdrawal in patients with idiopathic hyperprolactinemia and prolactinomas. Data Sources: PubMed, the Cochrane
Autologous dermal fibroblasts may be useful in the treatment of diabetic skin wounds. We hypothesized that cultured fibroblasts or cultured keratinocytes would not only survive in a hyperglycemic wound environment but also enhance the rate of re-epithelialization. We previously developed a new porcine model of delayed cutaneous wound healing in the diabetic pig. Full thickness wounds were created
To find a controller that provides the maximal stability margin to an LTI system under rank-one perturbations is a quasiconvex problem. In the paper, the dual quasiconvex problem is obtained, using the convex duality arguments in the Hardy space H∞. It is shown that the dual problem can be viewed as minimization of a "length" of uncertainties that destabilize the system. Several examples establish
Clin Microbiol InfectAbstract Propionibacterium acnes is a common and probably underestimated cause of delayed joint prosthesis infection. Bacterial biofilm formation is central in the pathogenesis of infections related to foreign material, and P. acnes has been shown to form biofilm both in vitro and in vivo. Here, biofilm formation by 93 P. acnes isolates, either from invasive infections (n = 45
Background Chronic immune stimulation appears to be associated with lymphoplasmacytic lymphoma (LPL)-Waldenström macroglobulinemia (WM); however, available information is sparse. We conducted, to our knowledge, the most comprehensive study to date to evaluate associations between a personal or family history of many immune-related and/or inflammatory disorders and the subsequent risk of LPL-WM. Me
The project “3D-Digging at Çatalhöyük” began in 2010 thanks to collaboration between Stanford University (Archaeological Center) and the University of California Merced with the scope to record, document (with different digital technologies) and visualize in virtual reality all the phases of archaeological excavation. Phase I (2010 excavation season) of the project was mainly oriented to test diff
