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The last decades have seen a renewed interest in the study of argumentation in archaeology, particularly in response to the overproduction of weak and unreliable interpretations and explanations. Concurrently, recent appeals for scientific transparency and efficiency in the management of archaeological information in digital form have stressed the necessity of explicitly showing the processes foll
Atherosclerosis is a major underlying cause of cardiovascular disease. Previous studies showed that inhibition of the co-stimulatory CD40 ligand (CD40L)-CD40 signaling axis profoundly attenuates atherosclerosis. As CD40L exerts multiple functions depending on the cell-cell interactions involved, we sought to investigate the function of the most relevant CD40L-expressing cell types in atheroscleros
Background: Fishing communities around Lake Victoria in sub-Saharan Africa have been characterised as a population at high risk of HIV-infection. Methods: Using data from a cohort of HIV-positive individuals aged 13–49 years, enrolled from 5 fishing communities on Lake Victoria between 2009–2011, we sought to identify factors contributing to the epidemic and to understand the underlying structure
Intellectual property rights (IPRs) represent a key concern for researchers and industry in basically all (high-tech) sectors. IPRs regularly figure prominently in scientific journals and at scientific conferences and lead to dedicated workshops to increase the awareness and “IPR savviness” of scientists. In 2015, Biotechnology Journal published a report from an expert meeting on “Synthetic Biolog
BACKGROUND: Viral infections of the upper airways are the most common cause for absence from work or school, and there is evidence for probiotic efficacy in reducing the incidence and severity of these infections.OBJECTIVES: We aimed to confirm the previously reported beneficial effects of Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2 against community-acquired common
Background: Concerns have been raised about increased gambling problems during the coronavirus disease (COVID-19) crisis, particularly in settings with high online gambling and risks of migration from land-based to riskier online-based gambling types. However, few non-self-reported data sources are hitherto available. The present study aimed to assess changes in the online- and land-based gambling
Environmental policy-making increasingly involves ministries beyond environment ministries. In particular, finance ministries are important, since they control the public budget and address environmental issues from a perspective different from environmental actors. The role of finance ministries is especially salient in the European Union's (EU) Emissions Trading System (ETS), which has been subj
OBJECTIVE In this study, we aimed to explore the mechanism by which TCF7L2 rs7903146 risk allele confers susceptibility to impaired glucose tolerance (IGT) or type 2 diabetes (T2D) in obese adolescents. RESEARCH DESIGN AND METHODS The rs7903146 variant in the TCF7L2 gene was genotyped in a multiethnic cohort of 955 youths. All subjects underwent an oral glucose tolerance test with the use of the O
OBJECTIVE: To assess the reliability of knee extensor and flexor muscle strength measurements in persons with late effects of polio. DESIGN: A test-retest reliability study. SUBJECTS: Thirty men and women (mean age 63 (standard deviation 6.4) years) with verified late effects of polio. METHODS: Knee extensor and flexor muscle strength in both lower limbs were measured twice 7 days apart using a Bi
Abstract Objective. The aim of this study was to validate externally the Swedish Lund-Malmö revised creatinine-based glomerular filtration rate (GFR) equations (LM Revised) in a Swedish cohort in comparison with the North American Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology (CKD-EPI) equations. Material and methods. The study included 1397 examinations [med
Background: Stroke and acute myocardial infarction (AMI) rank among the leading causes of mortality. Physical activity and exercise are recommended as part of rehabilitation after AMI to prevent cardiovascular events, but the importance for stroke prevention has not been investigated using population-based data. Objectives: To determine associations between participation in exercise-based cardiac
The associated production of Higgs and W bosons via vector-boson fusion is highly sensitive to the relative sign of the Higgs boson couplings to W and Z bosons. In this Letter, two searches for this process are presented, using 140 fb^{-1} of proton-proton collision data at sqrt[s]=13 TeV recorded by the ATLAS detector at the LHC. The first search targets scenarios with opposite-sign couplings o
Out-of-distribution (OOD) detection is a crucial step in ensuring robustness and trustworthiness for deep learning (DL) models. This is particularly important for classification tasks in medical applications. Previous work has shown that point-of-care ultrasound (POCUS) imaging combined with a DL classification network could improve access to early breast cancer diagnosis. In this work, we investi
This study explores the online communication strategies of anti-tourism movements to evaluate their potential contributions to place branding—a topic that has received limited scholarly attention. While prior research often views such movements as antagonistic to place branding efforts, we challenge this assumption. Through an analysis of nine movements across five countries, we apply the typology
Biological neural network functionality depends on the vast number of connections between nodes, which can be challenging to implement artificially. One radical solution is to replace physical wiring with broadcasting of signals between the artificial neurons. We explore an implementation of this concept by light emitting/receiving III-V semiconductor nanowire neurons in a quasi-2D waveguide. They
Background Long-term pathological breathlessness is a life-limiting symptom that risks taking control of the individual’s life. We aimed to evaluate how locus of control (LOC), an individual’s perceived control of present and past life events, relates to breathlessness in a middle-aged general population. Methods A population-based, cross-sectional analysis of people aged 50–64 years was conducted
Background: Cleft lip with cleft palate (CLP) is a congenital condition that affects both the oral cavity and the lips. This study estimated the prevalence and mortality of CLP using surveillance data collected from birth defect registries around the world. Methods: Data from 22 population- and hospital-based surveillance programs affiliated with the International Clearinghouse for Birth Defects S
Purpose: To evaluate the association between a previously published 313 variant–based breast cancer (BC) polygenic risk score (PRS313) and contralateral breast cancer (CBC) risk, in BRCA1 and BRCA2 pathogenic variant heterozygotes. Methods: We included women of European ancestry with a prevalent first primary invasive BC (BRCA1 = 6,591 with 1,402 prevalent CBC cases; BRCA2 = 4,208 with 647 prevale
In this paper, we revisit the problem of estimating the relative pose from a sparse set of point-correspondences. For each point-correspondence we also estimate the relative depth, i.e. the relative distance to the scene point in the two images. This yields an additional constraint, allowing us to use fewer matches in RANSAC to generate the pose candidates. In the paper we propose two novel minima
