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Designing Collective Action: Problems of Local Water Management in Tiruchi District

A wide range of factors shapes irrigation institutions and collective action with regard to irrigation. They include the distribution of land across irrigation command areas and across classes, land tenure systems, access to new technology such as bore wells, the availability and cost of electricity and other energy sources for lifting groundwater, and, above all, state policies related to irrigat

Procedural Volume and Outcomes With Radial or Femoral Access for Coronary Angiography and Intervention

Objectives The study sought to evaluate the relationship between procedural volume and outcomes with radial and femoral approach. Background RIVAL (RadIal Vs. femorAL) was a randomized trial of radial versus femoral access for coronary angiography/intervention (N = 7,021),which overall did not show a difference in primary outcome of death, myocardial infarction, stroke, or non-coronary artery bypa

The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancer.

Nitrogen-containing heterocyclic compounds are an important class of molecules that are commonly used for the synthesis of candidate drugs. Phosphatidylinositol-4-phosphate 5-kinase-α (PIP5Kα) is a lipid kinase, similar to PI3K. However, the role of PIP5K1α in oncogenic processes and the development of inhibitors that selectively target PIP5K1α have not been reported. In the present study we repor

The Street Art World

In recent years, street art has become embedded in popular culture and received growing attention from the art market and art institutions. Work by street artists has entered galleries, auction houses and museums, and some artists have been given the opportunity to create large-scale sanctioned public art projects. Simultaneously, widespread photographic documentation of street artworks and the ci

Defining a strategy of integration of packaging development into product development

1 INTRODUCTION In a global and highly competitive economy, companies have now adopted an increasingly integrated ap-proach to product development. However, packaging logistics has been left out from this integration trend. The reasons are multiple: first packaging is not considered to be an integral part of the product, so it is not part of the product “culture” of the company. In most companies,

Respiratory Disorders In Two Workers Of Customs Depositories Occupationally Exposed To Mouldy Tobacco

Work-related respiratory symptoms, including dyspnoea, cough, fever, tiredness and malaise, were recorded in two customs officers employed in 2 depositories of confiscated cigarettes, of which one showed signs of dampness. Microbiological sampling of the air and the cigarettes stored in a damp depository revealed the presence of potentially pathogenic fungi and bacteria and the biochemical markers

Recommendations for the standardization and interpretation of the electrocardiogram: part II: electrocardiography diagnostic statement list a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society Endorsed by the International Society for Computerized Electrocardiology

This statement provides a concise list of diagnostic terms for ECG interpretation that can be shared by students, teachers, and readers of electrocardiography. This effort was motivated by the existence of multiple automated diagnostic code sets containing imprecise and overlapping terms. An intended outcome of this statement list is greater uniformity of ECG diagnosis and a resultant improvement

Bridging the communicative gap between a person with dementia and caregivers. A nursing perspective

Popular Abstract in Swedish ?Överbrygga det kommunikativa gapet mellan personer med en demenssjukdom och deras vårdare. Ett omvårdnadsperspektiv? En problematik i omvårdnaden av personer med långt framskriden demenssjukdom är hur vårdare skall tolka och förstå den demensdrabbade så att omvårdnaden kan anpassas till dennes behov. Forskning tyder på att vissa reaktioner, bland annat aggressiva handThe aim was to explore possible areas and sources that could inform the care for people with dementia. These were the people with dementia themselves, nurses reflective discussions about caring, nurse-patient interaction together with information from close family members, and the previous personality and sense of coherence of people with dementia in relation to behaviour during the disease as rel

Virus tropism and neutralization response in SIV infection

Popular Abstract in Swedish Sedan 1981, då de första fallen av AIDS beskrevs, har 25 miljoner människor dött på grund av att de har blivit smittade av immunbristviruset HIV . Det finns idag mer än 40 miljoner människor som lever med HIV eller AIDS. SIV är apsläktets variant på HIV och orsakar normalt ingen sjukdom hos sina värddjur som är olika afrikanska apor, men då asiatiska apor, t. ex. makakeSimian immunodeficiency virus (SIV) infections in macaques are commonly used as models to study the pathogenesis of human immunodeficiency virus (HIV). Both SIV and HIV normally use the CD4 receptor and an additional coreceptor for cell entry. The most common coreceptors used by HIV are CCR5 and CXCR4. SIV use CCR5 and rarely CXCR4 but may use other coreceptors as alternatives. We have studied vi

”Har du PMS, eller?” En kvantitativ studie över psykosociala faktorers samband med premenstruellt syndrom.

Psykosociala faktorers samband med PMS undersöktes genom en webbaserad enkätundersökning som besvarades av 1320 svensktalande kvinnor och transpersoner med aktiv menscykel. Studien visade samband mellan höga nivåer av PMS och att bo tillsammans med barn eller partner samt att ha en mindre stöttande partner och låg relationstillfredställelse. Personer med en låg utbildningsnivå, egna erfarenheter aThe association between PMS and psychosocial factors was studied using the responses of 1320 women and transgender people with an active menstrual cycle to a Swedish web-based survey. Living with children or a romantic partner was associated with higher levels of PMS, in addition to low relational satisfaction and a less supportive partner. Premenstrual Coping, Perfectionism and Silencing the Self

Den från mervärdesskatt undantagna värdepappershandeln: en jämförelse av tolkning och tillämpning av undantagsregeln i EU-rätt och svensk rätt

Värdepappershandel tillsammans med annan finansiell verksamhet har undantagits från mervärdesskatteplikt inom EU sedan 1977, när Direktivet 77/388/EEC lagstiftades. Ursprungligen stadgades undantaget för dessa finansiella tjänster på grund av skattetekniska problem som uppkommer vid framställande av det beskattningsbara underlaget. Direktivet, som sedermera har ersatts av Direktivet 2006/112/EC (tTrade in securities along with other financial activities has been enjoying the VAT exempt status within the EU since 1977, when Directive 77/388/EEC was passed. The VAT exemption for the financial services was originally enacted due to the difficulties relating to defining the taxable amount for the VAT purposes. The mentioned Directive, which has consequently been replaced by Directive 2006/112/

EU and International Treaties with Third Countries - Can EU fulfil legal expectations in areas of shared competence as IP under TTIP?

Denna uppsats bygger på forskning inom den komplexa juridiska situationen bakom EU’s externa agerande och konflikten mellan externa och interna juridiska spörsmål inom områden med delad kompetens inom Unionen. EU’s lagstiftning, genom sin egen struktur, har en unik position inom hierarkin för rättskällor. Av de i uppsatsen presenterade rättsfallen och dokumentationen i övrigt kan man utläsa att deThis thesis is based on research into the area of the complex legal situation behind EU’s external affairs with the conflict between external and internal legal matters in regards to the area of shared competences within the Union. EU legislation, by its own structure, has a unique position in the hierarchy of laws. As can be seen by case law and documentation presented here it also contains its o

The "Black Butterflies": Color in God Help the Child and the Inverted White Gaze

The discourse on beauty has primarily been focused on the white gaze to prescribe its normative standards. The white gaze conceptualizes the way in which beauty is dwelled on within society: the foisting of Caucasian-looking beauty canons on black women, and the veneration of whiteness as superior. Black bodies are vanguards, either being desired or erased. In literature, the expression “white gaz

Immune evasion by acquisition of complement inhibitors: The mould Aspergillus binds both factor H and C4b binding protein

Pathogenic fungi represent a major threat particularly to immunocompromised hosts, leading to severe, and often lethal, systemic opportunistic infections. Although the impaired immune status of the host is clearly the most important factor leading to disease, virulence factors of the fungus also play a role. Factor H (FH) and its splice product FHL-1 represent the major fluid phase inhibitors of t

Diabetes mellitus and risk of prostate cancer - A focus on shared risk factors and survivor bias

Popular Abstract in Swedish Prostatacancer är den vanligaste formen av cancer hos män i Sverige och ungefär 10 000 män diagnosticeras årligen. Prostatacancer tros orsakas av en kombination av ärftliga faktorer och miljö-/livsstilsfaktorer. De enda väletablerade riskfaktorerna för prostatacancer är ålder, etnicitet och ärftlighet inom familjer. För att kunna arbeta med förebyggande av denna sjukdomProstate cancer (PCa) is a heterogenous disease including very aggressive lethal tumors to incidentally discovered clinically insignificant tumors. Age, ethnicity, and family history are the only established risk factors. Type 2 diabetes mellitus (T2D) has been found to associate with increased overall cancer risk but with lower risk of specifically PCa. T2D is initially associated with increased

Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials.

Many patients with asthma or chronic obstructive pulmonary disease (COPD) routinely receive a combination of an inhaled bronchodilator and anti-inflammatory glucocorticosteroid, but those with severe disease often respond poorly to these classes of drug. We assessed the efficacy and safety of a novel inhaled dual phosphodiesterase 3 (PDE3) and PDE4 inhibitor, RPL554 for its ability to act as a bro

Tasquinimod Modulates Suppressive Myeloid Cells and Enhances Cancer Immunotherapies in Murine Models

A major barrier for cancer immunotherapy is the presence of suppressive cell populations in patients with cancer, such as myeloid-derived suppressor cells (MDSC) and tumor-associated macrophages (TAM), which contribute to the immunosuppressive microenvironment that promotes tumor growth and metastasis. Tasquinimod is a novel antitumor agent that is currently at an advanced stage of clinical develo