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Design, synthesis, And applications of galectin modulators in human health

Over the last decade, the family of galectin proteins has been identified as key regulators of important biological processes. They bind β-D-galactopyranoside residues in glycoconjugates, and by presenting multiple binding sites, within one galectin or by forming dimers or multimers, they can cross-link glycoproteins and form galectin-glycoprotein lattices. Such lattices formed on the cell surface

The structural basis for complement inhibition by gigastasin, a protease inhibitor from the giant Amazon leech

Complement is crucial to the immune response, but dysregulation of the system causes inflammatory disease. Complement is activated by three pathways: classical, lectin, and alternative. The classical and lectin pathways are initiated by the C1r/C1s (classical) and MASP-1/MASP-2 (lectin) proteases. Given the role of complement in disease, there is a requirement for inhibitors to control the initiat

The Hidden Side of Complement Regulator C4BP : Dissection and Evaluation of Its Immunomodulatory Activity

C4b-binding protein (C4BP) is a well-known regulator of the complement system that holds additional and important activities unrelated to complement inhibition. Recently, we have described a novel immunomodulatory activity in the minor C4BP(β-) isoform directly acting over inflammatory phagocytes. Here we show that incorporation of the β-chain to the C4BP α-chain oligomer interferes with this immu

Solar and geomagnetic activity reduces pulmonary function and enhances particulate pollution effects

Background: Increased solar and geomagnetic activity (SGA) may alter sympathetic nervous system activity, reduce antioxidant activity, and modulate physiochemical processes that contribute to atmospheric aerosols, all which may reduce pulmonary function. Objectives: Investigate associations between forced expiratory volume at 1 s (FEV1) and forced vital capacity (FVC) with SGA, and assess whether

Cosmology from Strong Interactions

A wealth of theoretical and phenomenological information about Quantum Chromodynamics at short and long distances collected so far in major collider measurements has profound implications in cosmology. In this review, we give a brief discussion of major implications of strongly-coupled dynamics of quarks and gluons and effects of their collective motion in physics of early Universe and in astrophy

Is there a change in myocardial nonlinearity during the cardiac cycle?

The distortion of a sound wave during propagation results in progressive transfer of the energy from fundamental to higher harmonics, and is dependent on the nonlinearity of the medium. We studied if relative changes in acoustical nonlinearity occur in healthy myocardium during the cardiac cycle. Radiofrequency data were acquired from transthoracic echocardiography (2.5 and 3.5 MHz), parasternal l

Alien Octopodes: Öyvind Fahlström's Du gamla, Du fria, and the Institutional Practice of Swedish Experimental Feature Films

The aim of this master’s thesis is to investigate the discursive networks and production contexts of the rare and insular phenomena of Swedish experimental features. As a point of departure, the tentative and limited filmography of Swedish artist Öyvind Fahlström is expanded upon, as the thesis present a unique case study on his first and only feature film Du gamla, Du fria (“Provocation”, 1972).

Studenters attityder till försäljning av sexuella tjänster

Syftet med uppsatsen är att få ökad kunskap om studenters attityder till försäljning av sexuella tjänster. En enkätundersökning på Lunds universitet har genomförts under våren 2018. Uppsatsen testar hypotesen att kontexten som dessa studenter växt upp i med rådande sexköpslagstiftning utgör en starkare påverkan än trenden med en mer liberal inställning till försäljning av sexuella tjänster. Det teThis essay’s purpose is to gain increased knowledge about students’ attitudes towards the sale of sexual services. An online survey was conducted at Lund’s university during the spring of 2018. The essay tests the hypothesis that the context where these students grew up, with the Swedish sex purchase legislation, constitutes a stronger influence than the trend of a more liberal attitude towards th

Implementing the Right to Access to Justice for Persons with PTSD in Swedish Asylum Proceedings

By combining a legal doctrinal study and an empirical interview study, this thesis examines the implementation of the right to access to justice under article 13 of the Convention on the Rights of Persons with Disabilities for persons who due to post-traumatic stress syndrome have difficulties accounting for their stories in asylum proceedings. The starting point is that persons with PTSD likely w

Vad har väl bönderna att klaga över? En studie av problemen på landsbygden i Folkrepubliken Kina

I och med Hu Jintaos och Wen Jiabaos tillträde till makten har den kinesiska regeringens fokus kommit att flyttas från ren ekonomisk utveckling till att i högre grad än tidigare fokusera på att minska klyftorna mellan stad och landsbygd. Denna uppsats undersöker några av de problem som centralregeringen ser på landsbygden idag, samt några av de lösningar som presenterats. I undersökningen av situaSince Hu Jintao and Wen Jiabao took office the focus of the Chinese government has been less on pure economic development than before and more on developing the countryside. This paper investigates some of the problems the central government sees in the countryside as well as some of their solutions to those problems. The book The Grain People: Will China’s Villages Disappear? (Liangmin-Zhongguo n

Corporate Migration and its Implications for the Protection of Creditors - Recent Developments in the Case Law of the European Court of Justice

This thesis addresses the correlation between creditor protection and thecross-border seat transfer of companies in the light of the case law of the European Court of Justice concerning the freedom of establishment of undertakings. After the restrictive outcome of Daily Mail, the judgment of the European Court of Justice in Centros took the legal community by surprise. The following cases of Übers

The current false lumen endograft and clinical experience for false lumen occlusion in chronic aortic dissection

False lumen management of chronic aortic dissections has evolved during the past decade. Thoracic endovascular aortic repair (TEVAR) continues to be the mainstay of endovascular dissection treatment and relies on the adequate sealing of the proximal entry tear. However, TEVAR alone often fails to achieve aortic remodeling due to persistent distal retrograde perfusion of the false lumen with contin

Clinical impact of intraprocedural stent thrombosis during percutaneous coronary intervention in patients treated with potent p2y12 inhibitors -A validate-swedeheart substudy

BACKGROUND: The clinical importance of intraprocedural stent thrombosis (IPST) during percutaneous coronary intervention in the contemporary era of potent oral P2Y12 inhibitors is not established. The aim of this study was to assess IPST and its association with clinical outcome in patients with myocardial infarction undergoing percutaneous coronary intervention with contemporary antithromboticmed

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Forskning om högre utbildning 15–16 MAJ 2018 | LUNDS UNIVERSITET Contents First semester students’ perspectives on writing .................................................................................................. 4 Normer och värden i naturvetenskapliga ämnesmiljöer – får det betydelse för blivande lärares professionsutveckling? ............................................................

https://www.ahu.lu.se/fileadmin/user_upload/ahu/PDF/Abstracts_Forskning_om_h%C3%B6gre_utbildning_2018.pdf - 2026-05-16

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At the End of the World Newsletter – 15 September 2023 At the End of the World Newsletter – 15 September 2023 Dear all, This is the third newsletter for the  At the End of the World research program, housed at Lund University. If you’re receiving this email, it’s because you’ve been subscribed to our mailing list. Below, we’ll fill you in on some exciting events during the autumn 2023 academic ter

https://www.endoftheworld.lu.se/at-the-end-of-the-world-newsletter-15-september-2023/ - 2026-05-21

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At the End of the World Newsletter – 16 June 2025 This is the 10th newsletter for the At the End of the World research program, housed at Lund University. It is the second newsletter from our third year of activity. If you’re receiving this email, it’s because you’ve subscribed to our mailing list. Below, we’ll fill you in on some upcoming events and also what we've been up to since the last newsl

https://www.endoftheworld.lu.se/at-the-end-of-the-world-newsletter-16-june-2025/ - 2026-05-21

GLOWKeynote

GLOWKeynote Constraining Local Dislocation dialect-geographically Gertjan Postma Meertens Instituut Amsterdam gertjan.postma@meertens.knaw.nl GLOW-36, Lund, 3-5 April 2013 V-T-AGR versus V-AGR-T in Dutch dialects 1 Structure • The problem: order reversal - syntax or postsyntax? • The role of dialectology • Deviant structures V-pron-T and V-AGR-T in Dutch • A fundamental isogloss cuts the Dutch dia

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_glow36/Handouts_and_Presentations/Postma.pdf - 2026-05-23

Publications Archive - Page 43 of 43 - The Raoul Wallenberg Institute of Human Rights and Humanitari

Publications Archive - Page 43 of 43 - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Pro

https://rwi.lu.se/publications/page/43/ - 2026-05-23

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1 Filologkongressen IX, Lund Tisdag 12 maj 11.30–12.30 Session 4: Textutgivningsworkshop med Stephan Borgehammar ”Early Thirteenth-Century Sermons from Alvastra Abbey – Editorial Problems” If it originated in Sweden, the collection of sermons found in Uppsala University Library ms. C 37 is the earliest Swedish example of sermon writing to have survived. It is also the only example of sermons from

https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/Filologkongressen_intro.pdf - 2026-05-23