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Importance of individual residues in hydrophobic patch PLVIVGL (1481-1487) in FV-Short for synergistic TFPIα cofactor activity with protein S, an alanine-scanning study: AlphaFold-mediated prediction of FV-Short/TFPIα/protein S trimolecular complex structure

BackgroundIn the splice variant factor (F)V-Short, 702 residues are deleted from the B domain, resulting in exposure of an acid region (AR2; 1493-1537) that binds TFPIα. FV-Short and protein S serve as synergistic TFPIα cofactors in inhibition of FXa. In the preAR2 region, a hydrophobic patch PLVIVGL (1481-1487) is crucial for synergistic TFPIα-cofactor activity and assembly of FV-Short, TFPIα, an

Transposable Elements in Neural Progenitor Cells

More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. Transposable elements comprise about 50% of the genome and co-exist as symbio

Applying the Kraljic model to the construction sector - the case of a prefab housing factory

The purchasing strategies in the construction industry have been considered by many writers in construction management as short-term and arms-length. However, a different picture is portrayed in the manufacturing industry, where the purchasing strategies are mostly long-term to secure supply for production. Industrialized building is at the crossroad between construction and manufacturing, which r

A method to stretch the retina in vitro and monitor effects on Müller glial cells

The retina is a thin tissue layer on the inside of the eye and may be subject to tractional forces in diseases like myopia, retinoschisis, and retinal detachment. Müller glial cells (MGCs) are the only cells spanning the entire retinal thickness and hypothetically respond to mechanical stress imposed across retinal layers. We designed a device to apply force in vitro perpendicular to the retinal s

Publications from the sociology of law department 2020

Publications from the Sociology of Law Department at Lund University Lund Studies in Sociology of Law (ISSN 1403-7246) 1 Hydén, Håkan (red) Rättssociologi – då och nu: En jubileumsskrift med anledning av rättssociologins 25 år som självständigt ämne i Sverige 148 sidor ISBN 91-89078-23-3 (1997) 2 Hydén, Håkan & Alf Thoor (red) Rätt i förändring: Om kristendenser i svensk rätt 146 sidor ISBN 91-890

https://www.soclaw.lu.se/en/sites/soclaw.lu.se.en/files/2020-12/publications_from_the_sociology_of_law_department_2020.pdf - 2026-05-16

The impact of a crisis on the provision of assistive technology in Sweden : the case of COVID-19

The entitlement to access assistive technology (AT) is fundamental for all individuals. However, challenges encountered during societal crises can significantly impact opportunities for participation and engagement among AT users. Understanding the implications of crises and disasters on AT provision along with their repercussions for end users is crucial. This research endeavors to investigate th

Genome dynamics and virulence in the human pathogen Candida glabrata

Although the yeast Candida glabrata is considered to be a part of the commensal microflora in healthy individuals, during the last years it has been frequently isolated from patients with mucosal and systemic fungal infections. Now it is considered as the second most frequently isolated pathogenic yeast after Candida albicans. Despite its name, C. glabrata is phylogenetically a closer relative to

South Asian Nationalisms: Guest Editors' Introduction

This article intends to raise questions related to nationalism in South Asia, while also addressing the rationale for this special issue. Is nationalism a monolithic construct based on a European precedent or is it something much larger that is developed pluralistically in a variety of contexts around the world? If the latter is true, which is our position, then how do we go about studying the var