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Biotechnological Potential of Bdellovibrio and Like Organisms and Their Secreted Enzymes

Bdellovibrio and like organisms (BALOs) are obligate predatory bacteria that selectively prey on a broad range of Gram-negative bacteria, including multidrug-resistant human pathogens. Due to their unique lifestyle, they have been long recognized as a potential therapeutic and biocontrol agent. Research on BALOs has rapidly grown over the recent decade, resulting in many publications concerning mo

GFAp and tau protein as predictors of neurological outcome after out-of-hospital cardiac arrest : A post hoc analysis of the COMACARE trial

Aim: To determine the ability of serum glial fibrillary acidic protein (GFAp) and tau protein to predict neurological outcome after out-of-hospital cardiac arrest (OHCA). Methods: We measured plasma concentrations of GFAp and tau of patients included in the previously published COMACARE trial (NCT02698917) on intensive care unit admission and at 24, 48, and 72 h after OHCA, and compared them to ne

Quantifying the impacts of urban morphology on modifying microclimate conditions in extreme weather conditions

It is well-known that the morphology of urban areas modifies the variations of climate variables at microscale; known as microclimate conditions. The complexity of urban morphology can lead to undesired wind conditions or excessive air temperature; particularly in extreme weather conditions. This study attempts to quantify the impacts of urban morphology on the evolution of wind speed and air temp

Knee extensor strength and body weight in adolescent men and the risk of knee osteoarthritis by middle age

OBJECTIVES: To assess the extent to which knee extensor strength and weight in adolescence are associated with knee osteoarthritis (OA) by middle age.METHODS: We studied a cohort of 40 121 men who at age 18 years in 1969/1970 underwent mandatory conscription in Sweden. We retrieved data on isometric knee extensor strength, weight, height, smoking, alcohol consumption, parental education and adult

Sustainability of mega water diversion projects : Experience and lessons from China

Water availability and water demand are not evenly distributed in time and space. Many mega water diversion projects have been launched to alleviate water shortages in China. This paper analyzes the temporal and spatial features of 59 mega water diversion projects in China using statistical analysis. The relationship between nine major basins is measured using a network analysis method, and the as

Lower incidence of procoagulant abnormalities during follow-up after creation of the Fontan circulation in children.

OBJECTIVE: Children who undergo surgery for complex congenital cardiac disease are reported to be at increased thrombotic risk. Our aim was to evaluate long-term changes in the haemostatic system after surgery, to compare markers of activated coagulation in children having surgery with those in a healthy control population, and to relate them to adverse clinical outcome.Patients and methodsWe stud

n-CoDeR concept: unique types of antibodies for diagnostic use and therapy.

The n-CoDeR recombinant antibody gene libraries are built on a single master framework, into which diverse in vivo-formed complementarity determining regions (CDRs) are allowed to recombine. These CDRs are sampled from in vivo-processed and proof-read gene sequences, thus ensuring an optimal level of correctly folded and functional molecules. By the modularized assembly process, up to six CDRs can

Underlåtenhet att avslöja våldtäkt - En åskådares skyldighet att agera eller en möjlighet att undkomma ansvar?

Bestämmelsen om underlåtenhet att avslöja våldtäkt har sällan åberopats i praktiken. Under 2017 prövades brottet av Högsta domstolen vars dom har tolkats i ett annat våldtäktsmål. Uppsatsens huvudsakliga syfte är att analysera de objektiva förutsättningarna för straffbarhet för åskådare vid underlåtenhet att avslöja våldtäkt samt analysera hur bestämmelsen tillämpas i praktiken. Med det avses såväThe provision regarding failure to reveal an ongoing rape has seldom been invoked in court. However, the crime was tried by the Swedish Supreme Court in 2017 and the judgment has been interpreted in another case of rape. The main purpose of the essay is to analyze the objective prerequisites for criminal responsibility regarding spectators in the event of failure to reveal an ongoing rape. This en

Tax Challenges of the Digital Economy: Does a Withholding Tax on Certain Digital Transactions Solve the Problem of Missing Taxation Rights, While Being In Line with EU-Law and the OECD Model Convention?

This thesis investigates whether the implementation of a withholding tax on financial transactions obtained by the provision of certain digital services could solve the current problem of missing taxation rights regarding the income of highly digitalized multinational business models. Furthermore, the thesis aims to determine whether such tax could be in line with European Union law and the model

The Humane School

My diploma project is a design proposal for a Rudolf Steiner School in Sirende, a village 12 km outside Kitale Town, Kenya. On Initiative taken by the anthroposophical association Föreningen Sofia in Sweden, a Steiner school opened in Sirende in year 2008. Today the school is in a very bad condition with over crowded classrooms and poor sanitary conditions. The need for a new school building is ur

Leveraging brand co-creation in a digital era: An IKEA case study

Purpose: The purpose is to examine how IKEA works with customer brand co-creation and how it can be further leveraged in the digital era. Methodology: This paper adopts a qualitative case study method, where the primary data consists of an interview with a Social Media Specialist with pre-existing knowledge of brand co-creation at IKEA in Sweden. Furthermore, research about IKEA and the ways they

Tongue articulation of front close vowels in Stockholm, Gothenburg and Malmöhus Swedish

Articulatory data were collected for the Swedish vowels /iː, yˌ, ʉ̟ː/ from nine speakers each of Stockholm, Gothenburg, and Malmöhus Swedish, and the tongue positions and their dynamics analysed using Functional Data Analysis (FDA). Results showed that the general tongue positions for /iː/ and /yː/ are similar and clearly different from /ʉ̟ː/ in all three dialects. Variation within the Stockholm a

Tolerance and Immunity: Opposite Outcomes of Microbial Antigen Stimulation

The immune system is remarkable in many ways. It exerts immunity to defend us from foreign pathogens, while it is also responsible for maintaining tolerance to avoid autoimmune diseases and allergy. This thesis includes three separate papers concerning both tolerance and immunity. In paper I we report that repeated antigen stimulation results in an increased proportion of Foxp3+ cells in the CD4+