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Development of a Molecular Imprinting-Based Surface Plasmon Resonance Biosensor for Rapid and Sensitive Detection of Staphylococcus aureus Alpha Hemolysin From Human Serum

Stapylococcus aureus is a common infectious agent in e.g. sepsis, associated with both high mortality rates and severe long-term effects. The cytolytic protein α-hemolysin has repeatedly been shown to enhance the virulence of S. aureus. Combined with an unhindered spread of multi drug-resistant strains, this has triggered research into novel anti virulence (i.e. anti α-hemolysin) drugs. Their func

Relationship between water quality and macro-scale parameters (land use, erosion, geology, and population density) in the Siminehrood River Basin

To date, few studies have investigated the simultaneous effects of macro-scale parameters (MSPs) such as land use, population density, geology, and erosion layers on micro-scale water quality variables (MSWQVs). This research focused on an evaluation of the relationship between MSPs and MSWQVs in the Siminehrood River Basin, Iran. In addition, we investigated the importance of water particle trave

Engaging with the general public on critical raw materials through the medium of electronics repair workshops.

The issue of Critical Raw Materials (CRMs) and potential interruptions to their supply andavailability due to concerns such as shortages, trade restrictions or geopolitical considerations are topicsthat are relatively unknown to the general public. Education and the dissemination of this informationamongst the general public has been promoted as a key factor in addressing this and enabling thetran

Autoimmune hematological disorders

Autoimmune diseases are disorders where the immune system reacts against self-antigens to cause disease. Autoimmune disorders occur in about 5-7% of the population, although many individuals have no symptoms. In all, there are more than 70 different disorders, most of which are uncommon, apart from rheumatoid disease and autoimmune thyroiditis. Autoimmune diseases are clinical syndromes mediated b

Calprotectin as a sepsis diagnostic marker in critical care : a retrospective observational study

Diagnosing sepsis in critical care remains a challenge due to the lack of gold-standard diagnostics. Calprotectin (S100A8/A9) has been proposed as a diagnostic marker to identify sepsis in critically ill patients. This study evaluated the diagnostic performance of calprotectin and C-reactive protein (CRP) to distinguish between sepsis and non-sepsis on intensive care unit (ICU) admission. Admissio

In Vitro Elimination of Highly Multidrug-Resistant Bacteria by the Lactic Acid Bacterial Drug Candidate ILP100

Introduction: Multidrug resistance (MDR) has been identified in wound bacterial isolates from Ukrainian war victims treated in Ukraine and across Europe. ILP100, a drug candidate for the treatment of skin wounds, is composed of a Limosilactobacillus reuteri expressing human chemokine CXCL12. In this study, the antimicrobial effects of ILP100 were tested on MDR bacteria isolated from wounds of Ukra

Reference tool for perceived quality - within the Sony Ericsson Product Business Unit Accessories Organization

Title Reference tool for perceived quality ? within the Sony Ericsson Product Business Unit Accessories Organization. Author Jakob Frey-Skött Supervisors Annika Olsson, Department of Design Sciences, Division of Packaging Logistics, Lund Institute of Technology, Lund University. Gunilla Wejfeldt, Head of Quality Assurance, Sony Ericsson Product Business Unit Accessories Organization. Problem

Effect of A-site substitutions on energy storage properties of BaTiO 3 -BiScO 3 weakly coupled relaxor ferroelectrics

Weakly coupled relaxors based on compositions (1-x) BaTiO 3 -xBiMeO 3 , where Me is a metal ion, have attracted attention as potential candidates for high-temperature high-energy density capacitors. However, the necessary Bi content is typically high with x = 0.3-0.4. In order to reduce problems associated with compatibility for base metal electrodes and due to additional problems due to Bi vol

Rapid detection of antibiotic resistance in positive blood cultures by MALDI-TOF MS and an automated and optimized MBT-ASTRA protocol for Escherichia coli and Klebsiella pneumoniae

Introduction: For fast and effective antibiotic therapy of serious infections like sepsis, it is crucial with rapid information about antibiotic susceptibility, especially in a time when the number of infections caused by multi resistant bacteria has escalated in the world. Methods: Here, we have used a semi-quantitative MALDI-TOF-MS based method for antibiotic resistance detection, MBT-ASTRA™, wh

Understanding virtual speakers

This thesis addresses how verbal comprehension is affected by seeing the speaker and in particular when the speaker is an animated virtual speaker. Two people visually co-present – one talking and the other listening, trying to comprehend what is said – is a central and critical scenario whether one is interested in human cognition, communication or learning. Papers I & II are focused on the e

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The introduction of a mollecular method to identify the Entoviruses based on the amplification sequecing and phylogenetic analysis of protein VPI was described. It was proved that this method reduces significantly the time required for the identification of the isolated Entoviruses and that it is very useful in the characterization of isolates which are difficult to typify by the routine immunoloi

Associating SOM Representations of Haptic Submodalities

We have experimented with a bio-inspired selforganizingtexture and hardness perception system whichautomatically learns to associate the representations of the twosubmodalities with each other. To this end we have developeda microphone based texture sensor and a hardness sensor that measures the compression of the material at a constant pressure. The system is based on a novel variant of the Self-

Extravert Surgical Resident Applicants Get Higher 360-Degree Evaluations From Coworkers

INTRODUCTION: 360-degree evaluations are used as an assessment in order to identify strengths and weaknesses of, or as a continuous evaluation for, residents. The aim of this study was to investigate the relationship between personality and ratings on 360-degree evaluations among surgical residency applicants. A secondary aim was to describe the personality profile of applicants for a surgical res

Low nanomolar affinity to major grass pollen allergen Phl p 5 as achieved in an unmutated human antibody-lineage ancestor

BACKGROUND: Group 5 allergens, such as Phl p 5 of timothy grass, are major contributors to grass pollen allergy. Antibody 212597 specific for this allergen was recently isolated by single cell sequencing of bone marrow B cells of a grass pollen-allergic subject. This antibody, although subjected only to a low level of hypermutation resulting in six amino acid substitution across the heavy and ligh

Forming the local starburst galaxy Haro 11 through hydrodynamical merger simulations

Haro 11 is a metal-poor, starburst galaxy believed to be the result of an ongoing merger, which is shaping the properties of the galaxy. In this study, we carry out a large suite of numerical simulations of a merger between two disc galaxies, to study possible origins of Haro 11 and understand under which conditions various features of the galaxy are formed. By varying galaxy parameters describing

European Resuscitation Council and European Society of Intensive Care Medicine Guidelines 2025 Post-Resuscitation Care

The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) have collaborated to produce these post-resuscitation care guidelines for adults, which are based on the International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations (CoSTR) pubished by the International Liaison Committee on Resuscitation (ILCOR). The topics cover