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Mechanical damage at the time of joint injury and the ensuing inflammatory response associated with elevated levels of pro-inflammatory cytokines in the synovial fluid, are reported to contribute to the progression to osteoarthritis after injury. In this exploratory study, we used a targeted proteomics approach to follow the progression of matrix degradation in response to mechanical damage and cy
This thesis will be concerned with one of the main concerns and highly discussed topics in the relationship between Article 102 TFEU and Intellectual Property Rights. Predominately, it will focus on the enforcement of IPR(s) as an abusive practise of dominance and whether a dominant undertaking has the ability to protect its IPR by refusing to licence its IPR to a third party. The main purpose wi
This thesis focuses on the librarian’s professional identity and how this is formed. The purpose of this study is, more specifically, to discover how the professional identity of the research librarians is constructed, and which professional identity positions are avaliable during Book a librarian-meetings at Lund university. By doing this I want to establish an understanding for what Book a libra
This research outlines the evolution of the manufacturing and industrial export structure of countries, Estonia, Lithuania, and Latvia since 1992 within the framework of Economic Complexity and the Product Space. The research reveals a relatively low level of specialization in the countries’ export structures and identifies a dual structure within the economy due to the foreign ownership of firms.
Like many other international human rights law instruments, the 1951 Convention relating to the Status of Refugees was written from a male perspective, which has resulted in that the refugee definition of the Convention historically has been interpreted through a framework of male experiences. For this reason, many asylum claims of female applicants have been ignored. In order to be granted refug
Building new wind farms is an important part in the transition to renewable energy. However these projects often require large investments, and the cost of upgrading the existing infrastructure - to allow for the connection of new parks - is a component that cannot be ignored. When several wind farms seek interconnections, they are forced to collaborate and financing the connection. This leads to
The objective of this exploratory study was to develop signal processing methods for assisting in the diagnosis of arteriovenous fistula stenosis on patients suffering from end-stage renal disease and undergoing haemodialysis treatments. The proposed method is based on the classification of vessels sounds utilizing parameter extraction from wavelets transform coefficients. The coefficients energy
When robots are working in dynamic environments, close to humans lacking extensive knowledge of robotics, there is a strong need to simplify the user interaction and make the system execute as autonomously as possible. For industrial robots working side-by-side with humans in manufacturing industry, AI systems are necessary to lower the demand on programming time and expertise. One central conce
This study focuses on the word accent opposition in a lesser known and endangered variety of Swedish–Estonian Swedish. The variety has been described as not making the tonal distinction between Accent 1 and Accent 2 words, but no systematic acoustic phonetic investigation has been carried out previously to confirm these descriptions. As materials, disyllabic words from read sentences, spontaneous
Innate immunity is important for the integrity of the host against potentially invasive pathogenic microorganisms in the environment. Antibiotic peptides with broad antimicrobial activity are part of the innate immune system. We investigated the presence of the cathelicidin, human cationic antimicrobial protein (hCAP-18), in the male reproductive system. We found strong expression of the hCAP-18 g
Since its emergence in late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has continuously evolved, giving rise to multiple variants that have significantly altered the trajectory of the COVID-19 pandemic. These variants have resulted in multiple waves of the pandemic, exhibiting characteristic mutations in the spike (S) protein that may have affected receptor interaction, tis
The 1976 premiere of Face to Face came at the height of director-screenwriter Ingmar Bergman's career. Prestigious awards and critical acclaim had made him into a leading name in European art cinema, yet today Face to Face is a largely overlooked and dismissed work.This book tells the story of its rise and fall. It presents a new portrait of Bergman as a political artist exploring a new medium wit
Psoriasis is a frequently occurring inflammatory skin disease characterized by thickened erythematous skin that is covered with silvery scales. It is a complex genetic disease with both heritable and environmental factors contributing to onset and severity. The CD18 hypomorphic PL/J mouse reveals reduced expression of the common chain of beta(2) integrins (CD11/CD18) and spontaneously develops a s
We study the Al-Salam-Chihara polynomials when q > 1. Several solutions of the associated moment problem are found, and the orthogonality relations lead to explicit evaluations of several integrals. The polynomials are shown to have raising and lowering operators and a second order operator equation of Sturm-Liouville type whose eigenvalues are found explicitly. We also derive new measures with re
There has been great interest in the rationales for transformative innovation policies (TIP), including those following a mission-oriented logic. However, few studies have investigated how public administration can effectively implement TIP. To study this, we first identify from existing literature four TIP governance tasks (creating legitimacy and leadership, coordination across levels/instrument
This chapter examines the evolution of social class segregation in the city of Landskrona during the twentieth century. The city’s population was initially spatially mixed with regards to social class but became more segregated with industrialization. The study reveals that the segregation of higher white-collar workers increased drastically from 1940 to 1960, with a concentration of this group in
Serum paraoxonase 1 (PON1) is a native lactonase capable of promiscuously hydrolyzing a broad range of substrates, including organophosphates, esters, and carbonates. Structurally, PON1 is a six-bladed β-propeller with a flexible loop (residues 70-81) covering the active site. This loop contains a functionally critical Tyr at position 71. We have performed detailed experimental and computational a
