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The Davies transformation is a method to transform the steering vector of a uniform circular array to another vector with Vandermonde form. However, this transformation can be highly sensitive to perturbations of the underlying ideal array model. In this paper, we describe a method for deriving a more robust transformation using optimisation techniques. The effectiveness of the method is illustrat
While immunomodulatory monoclonal antibodies (mAbs) have therapeutic efficacy against many tumors, few patients are cured. Attempting to improve their therapeutic efficacy we have applied the TC1 mouse lung carcinoma model and injected established subcutaneous tumors intratumorally with 3 weekly doses of various combinations of mAbs. Combinations of mAbs to CTLA4/PD1/CD137 (the 3 mAb combination)
The design of the 3 GeV linac for the MAX IV facility was done to provide the ability to host a future FEL in the hard X-ray as well as in the soft X-ray range. The linear accelerator, with its two bunch compressors, is now under commissioning. Through the years increasing details for the actual FEL have been discussed and presented. In parallel a steering group for the science case for a Swedish
Hydrogen is an element of fundamental importance for energy but hard to quantify in bulk materials. Neutron radiography was used to map . in situ loss of elemental hydrogen from beech tree wood samples during pyrolysis. The samples consisted of three wood cylinders (finished dowel or cut branch) of approximately 1 cm in length. The samples were pyrolyzed under vacuum in a furnace vessel that was p
Objectives: Gram-positive, anaerobic cocci (GPAC) can cause infections in humans. Only a few cases of bacteraemia with GPAC have been reported. We describe the clinical and microbiological characteristics of GPAC bacteraemia. Methods: A retrospective population-based study of GPAC bacteraemia 2012–2016 in southern Sweden was performed. GPAC were identified using matrix-associated laser desorption
The dermatofibrosarcoma protuberans family of tumors (DPFT) comprises cutaneous soft tissue neoplasms associated with aberrant PDGFBR signaling, typically through a COL1A1-PDGFB fusion. The aim of the present study was to obtain a better understanding of the chromosomal origin of this fusion and to assess the spectrum of secondary mutations at the chromosome and nucleotide levels. We thus investig
Background: The aim of this study was to describe out-of-hospital cardiac arrest (OHCA) survivors' ability to participate in activities of everyday life and society, including return to work. The specific aim was to evaluate potential effects of cognitive impairment. Methods and Results: Two hundred eighty-seven OHCA survivors included in the TTM trial (Target Temperature Management) and 119 match
The mass media constructs authority by creating 'intimacy at a distance' (John B. Thompson) between public figures and the people. This chapter argues that, over the course of the long nineteenth century, rulers both gained new possibilities for staging their authority through the emerging mass media, and lost control over this mediated staging under specific circumstances, often turning from mast
Part II of the European clinical guidelines for Tourette syndrome and other tic disorders (ECAP journal, 2011) provides updated information and recommendations for psychological interventions for individuals with tic disorders, created by a working group of the European Society for the Study of Tourette Syndrome (ESSTS). A systematic literature search was conducted to obtain original studies of ps
We formulate a version of the low-scale Majoron model equipped with an inverse seesaw mechanism featuring lepton-number preserving dimension-6 operators in the scalar potential. Contrary to its dimension-4 counterpart, we find that the model can simultaneously provide light and ultralight Majorons, neutrino masses and their mixing, while featuring strong first-order cosmological phase transitions
Aims: Resuscitated out-of-hospital cardiac arrest (OHCA) patients who remain comatose after hospital arrival are at high risk of mortality due to anoxic brain injury. MicroRNA are small-non-coding RNA molecules ultimately involved in gene-silencing. They show promise as biomarkers, as they are stable in body fluids. The microRNA 9-3p (miR-9-3p) is associated with neurological injury in trauma and
The purpose of this paper is to reflect on how potential circumventing media and communication technologies could potentially assist the information flow when authoritarian regimes decide to block the main channels, such as the Internet and the mobile phone networks. The point of departure is the recent Internet blackouts in countries in the Middle East and North Africa (MENA), such as Egypt, Bahr
We investigate the occurrence of water vapour signatures in a total of 10 red giants in the solar neighbourhood at mid-infrared wavelengths (12 pm). With the use of high resolution spectra from TEXES and synthesized spectra based on MARCS model atmospheres, we analyse the differences and discuss plausible causes. These include abundance adjustments, the addition of non-photospheric components (MOL
Many existing protocols for neuronal differentiation of human pluripotent cells result in heterogeneous cell populations and unsynchronized differentiation, necessitating the development of methods for labeling specific cell populations. Here we describe how microRNA-regulated lentiviral vectors can be used to visualize specific cell populations by exploiting endogenous microRNA expression pattern
Purpose City logistics projects often include urban consolidation centres (UCCs) to reduce the environmental impact of transportation by consolidating the goods flow in cities. However, there is limited knowledge about the actual environmental effects of such consolidation, e.g. in terms of number of vehicles in a city and the congestion, nuisances and emissions. The purpose of the paper is to mea
Thermostimulated and photostimulated luminescence of ZnWO4, ZnWO4:Fe and ZnWO4:MO Crystals irradiated at low temperatures by X-rays or UV photons was studied in the temperature range 4.2-300 K in order to clarify the creation and recombination processes of the elementary colour centres. The connection of the luminescence phenomena with the self-trapped holes has been revealed. (C) 2003 Published b
