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Negation and approximation as configurational construals in SPACE

This article is a window into conceptual space through antonyms, negated antonyms and antonyms modified by degree modifiers. It investigates native speakers’ understanding of negation in combination with BOUNDED antonymic adjectival meanings and also in relation to their interpretations of the approximating degree modifier, ‘almost’ in Swedish. The results of the investigation are compared with a

Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins

Pathogenic microbes have evolved sophisticated molecular strategies to subvert host defenses. Here we show that virulent bacteria interfere directly with Toll-like receptor (TLR) function by secreting inhibitory homologs of the Toll/interleukin-1 receptor (TIR) domain. Genes encoding TIR domain containing–proteins (Tcps) were identified in Escherichia coli CFT073 (TcpC) and Brucella melitensis (Tc

Balde, Jacobus

In the frame of an encyclopedic article, a surview of the famous baroque Jesuit author Jacob Balde's life and his diverse oeuvre of Latin poetry is given.

The Tie that Binds: Cosmopolitan Obligation and the Primacy of Institutions

I identify what I see as three aspects of contemorary cosmopolitan philosophy: A certain moral consciousness, a commitment to moral universalism, and an institutional implication of the first two. The third of these is often regarded as a fall-out or consequence of the other two. I argue instead that the institutional aspect should be regarded as primary and that a distinctive feature of cosmopoli

The Metonymic Access of Emotion Concepts

Examples from the affective domain have been plentifully employed for illustrating and sustaining the claims of the conceptual metaphor theory (Lakoff 1980, 1992, Kövecses 1986, 1990, 2000, King 1989, Yu 1995, Matsuki, 1995, Soriano-Salinas 2003, etc.). According to this position, affective concepts (as many other abstract concepts) are metaphorically structured, i.e. conceptualized in terms of mo

Jesus and the Scriptures: Problems of Authentication and Interpretation

As an introduction to the volume, this chapter discusses some of the methodological problems involved in assessing the questions of the historical Jesus’ engagement with the Scriptures of Israel. It is claimed that any method for studying the historical Jesus must take into account the two major tasks of Jesus research, viz. ‘authentication’ and ‘interpretation’. The article then discusses how ext

Knowledge spillover agents and regional development

It is widely recognised that knowledge and highly-skilled individuals as “carriers” of knowledge (i.e. knowledge spillover agents) play a key role in impelling the development and growth of cities and regions. In this chapter we discuss the relation between the mobility of talent and knowledge flows. In this context, several issues are examined, including the role of highly-skilled labour for regi

Protein nanoribbons template enamel mineralization

As the hardest tissue formed by vertebrates, enamel represents nature's engineering masterpiece with complex organizations of fibrous apatite crystals at the nanometer scale. Supramolecular assemblies of enamel matrix proteins (EMPs) play a key role as the structural scaffolds for regulating mineral morphology during enamel development. However, to achieve maximum tissue hardness, most organic con

Challenges and opportunities for cohesive ticketing and traffic information systems in the Greater Copenhagen region

Cross-border regions are characterised by many inherent challenges. Such challenges can include differences in languages, cultures, currencies, markets, labour market conditions, political visions and priorities, governance structures – to name but a few. Greater Copenhagen1 is no different in terms of the challenges it faces as a cross-border region.The aim of this study is to investigate the pos

Ferric carboxymaltose for iron deficiency at discharge after acute heart failure: a multicentre, double-blind, randomised, controlled trial

Background: Intravenous ferric carboxymaltose has been shown to improve symptoms and quality of life in patients with chronic heart failure and iron deficiency. We aimed to evaluate the effect of ferric carboxymaltose, compared with placebo, on outcomes in patients who were stabilised after an episode of acute heart failure. Methods: AFFIRM-AHF was a multicentre, double-blind, randomised trial don

Förväntningar på barn och trygghetspersoner i samband med barnahusbesök

Målgruppen för barnahus är barn som misstänks ha varit utsatta för brott såsom barnmisshandel och sexuella övergrepp. Barn kan besöka barnahus tillsammans med sina föräldrar. Om vårdnadshavaren, eller någon närstående till denne, är misstänkt kan barn hämtas till förhör utan vårdnadshavares vetskap eller samtycke. Barnet följs då av en trygg person som barnet känner från exempelvis förskolan eller