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Mergers of Authorities in Central Government: Role Ambiguities and Blame-Avoidance

Mergers of autonomous executive authorities in central government have become increasingly common, in particular in the Nordic countries. As compared to private sector mergers, the role of the principal (the central Government and its ministries) is more obscure in these mergers, this chapter argues. When problems arise in a merger, the ministry can take a step back and shift to a stakeholder posi

The language of eating and drinking: a window on Orang Asli meaning-making

We make in this chapter a first probe into the lexical domain of eating and drinking as it is construed in the Aslian languages, a branch of the Austroasiatic language family spoken by a majority of the Orang Asli of the Malay Peninsula. Fundamental to human experience and representation, the domain of ingestion has received increased linguistic attention in recent years. Setting out from our own

GaiaNIR - A future all-sky astrometry mission

With the launch of Gaia in December 2013, Europe entered a new era of space astrometry following in the footsteps of the very successful Hipparcos mission. A weakness of Gaia is that it only operates at optical wavelengths. However, much of the Galactic centre and the spiral arm regions are obscured by interstellar extinction. An obvious improvement on Gaia is to include the Near-Infra-Red (NIR) w

p53-mediated differentiation of the erythroleukemia cell line K562

The tumor suppressor gene p53 can mediate both apoptosis and cell cycle arrest. In addition, p53 also influences differentiation. To further characterize the differentiation inducing properties of p53, we overexpressed a temperature-inducible p53 mutant (ptsp53Val135) in the erythroleukemia cell line K562. The results show that wild-type p53 and hemin synergistically induce erythroid differentiati

A national study of health-related quality of life in patients with cancer of the base of the tongue compared to the general population and to patients with tonsillar carcinoma

Background: This exploratory, registry-based, cross-sectional study aimed to evaluate patients' health-related quality of life (HRQOL) in a subsite of oropharyngeal cancer: cancer of the base of the tongue (CBT). Methods: CBT patients, treated with curative intent, completed the EORTC QLQ-C30 and QLQ-H&N35 questionnaires 15 months after diagnosis. The HRQOL of CBT patients was compared to refe

Access to sexuality : Disabled people's experiences of multiple barriers

This chapter concerns disabled people’s experiences of barriers to accessing sexuality. It draws on an analysis of materials produced in ten projects by civil society organisations, including self-advocacy organisations, sexual rights organisations and organisations working on behalf of disabled people. These materials comprise books, handbooks, videos, websites and other online materials, and are

Design Beyond Zoning : Negotiating Architectural Form and Bulk Restrictions at HL23

This article uses Neil M. Denari’s HL23 condominium tower in West Chelsea, New York City, as the lens through which to focus on the architectural design pathway in discretionary reviews to negotiate architectural form and bulk restrictions. The argument states that creative architectural forms can appropriate an unorthodox site configuration in accord with planning objectives and that review proce

Bacterial expression of the scFv fragment of a recombinant antibody specific for Burkholderia pseudomallei exotoxin

The scFv antibody towards the Burkholderia pseudomallei exotoxin was previously constructed by phage display and exhibited good specificity towards the exotoxin. We report here the optimization of the scFv expression in an E. coli expression system. Four different E. coli strains (ER2537, TG1, HB2151, and XL1-Blue) were examined for optimal expression of the scFv protein. Two types of carbon sourc

Are Climate Negotiations Making Any Progress?

This paper provides a historical overview of the United Nations Framework Convention on Climate Change Conference of the Parties meetings and reviews the major outcomes of the meetings up to the most recent, which took place in Dubai. We describe how climate negotiations, agreements and policies have evolved, summarise the main points reached, and highlight the key concerns of low-income countries

Musiken som valbart ämne? En studie av lärarutbildningens kursplaner samt dess förhållande till musikämnet och Kp2000.

Utifrån tidigare forskning om och utvärderingar av musikämnets ställning i lärarutbildningen är syftet med förestående uppsats att ytterligare belysa musikämnets situation i den svenska lärarutbildningen såsom den manifesterar sig i kursplanerna på högskolor och universitet. Föremål för analys är samtliga lärarutbildningars kursplaner i det allmänna utbildningsområdet (AUO), som tillsammans med de

Introduction to Biostatistics

Knowledge in statistics is essential to draw solid conclusions from data. This chapter covers the basic concepts needed to navigate in the world of biostatistics, with the aim that the reader should know what to search for when encountering new situations. First, the chapter introduces basic concepts such as scales of measurement, relation between sample and population, and features of stochastic

Exploring housing policies in five Swedish municipalities : alternatives and priorities

Introduction: Housing shortage due to population growth within metropolitan areas, combined with an ageing population, has put pressure on current housing provision in Sweden. Thus, there is an urgent need to develop sustainable housing policies to accommodate the growing number of seniors in accessible home environments. This study aimed to gain an in-depth understanding of how municipalities cur

Impact on quality of life of an intervention providing additional information to patients with allergic contact dermatitis; a randomized clinical trial

Background: Allergic contact dermatitis can negatively impact an individual's daily life in terms of work and interpersonal relationships. Patch-tested individuals show an improved quality of life (QoL). Objectives: We aimed to assess the impact on QoL after patch testing and what value an intervention would have on QoL. Methods: Dermatology Quality of Life Index (DLQI) were assessed in participan

High-throughput three-dimensional cellular platforms for screening biophysical microenvironmental signals

Cells in vivo are subjected continuously to multiple biochemical and biophysical stimuli from their microenvironment that regulate cell fate and function. Although two-dimensional (2D) platforms to check cell responses to various microenvironmental factors have been established, these methods lack physiological relevance. Macroscale three-dimensional (3D) cell culture platforms were developed to p

Accuracy of MRI in early rectal cancer: national cohort study

Radiological staging of rectal cancer dictates subsequent patienttreatment. In early-stage disease, local excision is associatedwith reduced morbidity, mortality, and costs, and maintainsbowel continuity compared with surgery, where the whole orpart of the rectum is resected1–3. Nearly 90 per cent of patientswith T1 rectal cancer have N0 disease and are therefore potentially curable with local res