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IgG glycan hydrolysis by EndoS diminishes the pro-inflammatory properties of immune complexes from patients with SLE - a possible new treatment?

OBJECTIVE.: Systemic lupus erythematosus (SLE) is an autoimmune disease with chronic or episodic inflammation in several organ systems, related to the presence of circulating and tissue-deposited immune complexes (ICs) which stimulate leukocytes through FcγRs with subsequent inflammation. Treatment with EndoS, an IgG glycan hydrolyzing bacterial enzyme from Streptococcus pyogenes, has shown benefi

Den pedagogiska praktikens janusansikte: om det kommunikativa handlandets didaktiska villkor och konsekvenser

Popular Abstract in Swedish Villkoren för utbildning och undervisning förändras i väsentliga avseenden i takt med samhällets tilltagande komplexitet. Det är många gånger svårt för både lärare och elever att veta hur man på bästa sätt ska orientera sitt pedagogiska handlande. Med utgångspunkt från tre pedagogiska kontexter - grundskolan, de särskilda ungdomshemmen och grundskollärarutbildningen - p

Recognition of out-of-hospital cardiac arrest by medical dispatchers in emergency medical dispatch centres in two countries

Introduction Survival after out-of-hospital cardiac arrest (OHCA) remains low. Early recognition by emergency medical dispatchers is essential for an effective chain of actions, leading to early cardiopulmonary resuscitation, use of an automated external defibrillator and rapid dispatching of the emergency medical services. Aim To analyse and compare the accuracy of OHCA recognition by medical dis

Passive load control in backward-facing step flow by using chevrons

The ability of chevrons at the top edge of a backward-facing step to reduce downstream surface pressure fluctuations is investigated numerically. Three different chevron configurations are compared against a baseline case without chevrons. Low frequency reduction in the surface pressure fluctuations is observed for two of the configurations. The chevrons do not appear to have a significant effect

COASTAL EROSION AND BEACH NOURISHMENT IN SCANIA AS ISSUES IN SWEDISH COASTAL POLICY

I den här artikeln diskuteras kustpolicyförändringar i Sverige och deras dynamik, med stranderosion ochstrandfodring som exempel. Analysen baseras på Multiple Stream – modellen, som är en teoretisk modell förpolicyutveckling och agendasättning, utvecklad av samhällsvetaren John Kingdon (1984, 2003). Kustskydd ärinte ett separat policyområde i Sverige; åtgärder för att skydda allmän kust är ofta en

Early onset externalizing behaviors among forensic psychiatric patients : Identification in child and adolescent psychiatric services

Forensic psychiatric patients constitute a heterogeneous patient group, with common comorbidity within the externalizing spectrum. Increased knowledge on early antecedents in the pathway to severe mental illness and criminality is needed. In this study, we investigated early onset externalizing behaviors in three groups of forensic psychiatric patients 1) patients without contact with child and ad

Use of a surface emissions trap for enhancing the indoor air quality

Unsatisfactory indoor air quality (IAQ) can result from emissions of volatile organic compounds from the materials of the building. A surface emissions trap (cTrap) can be used to stop such emissions thus preventing them from reaching the indoor air. The present study concerned an apartment where the tenants experienced skin and mucous membrane irritation due to moisture-driven emissions from the

Ecoenzymatic stoichiometry can reflect microbial resource limitation, substrate quality, or both in forest soils

Many studies have used the relative activities of extracellular enzymes associated with microbial carbon (C), nitrogen (N) and phosphorus (P) acquisition to infer the relative C vs. nutrient limitation of the microbial community. However, recent experimental and theoretical evidence has shown that the use of ecoenzymatic ratio to infer limiting microbial resources may be invalid. We added the two

Model visualization : from micro to macro

Because of increasing demand, rapid development of in vitro and in vivo models to be used to study lung regeneration and lung repair has occurred during the last years. Even if imaging has always been an important tool in diagnosing disease and validating models, the current disease models, including three-dimensional (3D) lung models, put a higher demand on advanced imaging techniques. Moreover,

The Human Rights of Smuggled Migrants and Trafficked Persons in the Un Global Compacts on Migrants and Refugees

On 19 September 2016, the UNGA adopted the New York Declaration for Refugees and Migrants through which States committed to developing two compacts: one on refugees and one on safe, orderly and regular migration. The Zero Drafts of the compacts were published on 31 January 2018 and 5 February 2018, respectively. The move towards the discussion and adoption of the global compacts comes in part in r

No apparent increase in treatment uptake for gambling disorder during ten months of the covid-19 pandemic—analysis of a regional specialized treatment unit in Sweden

The COVID-19 pandemic and its impact on society has been suspected to affect gambling behaviors. Potentially, the pandemic crisis may result in increased problem gambling, for example, due to COVID-19-related psychological distress, unemployment, and financial difficulties. In ad-dition, the cancellation of sports in early parts of the crisis has been suspected to alter gambling behaviors. Policy

Grey Matter Segmentation in Spinal Cord MRIs via 3D Convolutional Encoder Networks with Shortcut Connections

Segmentation of grey matter in magnetic resonance images of the spinal cord is an important step in assessing disease state in neurological disorders such as multiple sclerosis. However, manual delineation of spinal cord tissue is time-consuming and susceptible to variability introduced by the rater. We present a novel segmentation method for spinal cord tissue that uses fully convolutional encode

A Framework for Intelligent Access and Compliance Assurance for High Capacity Transport

High Capacity vehicles (HCV) have dimensions outside general access rules. The High Capacity Transport (HCT) concept consists of roads, vehicles, operations, and regulations. The Intelligent Access (IA) framework gives access to roads only if compliance assurance schemes are used to ensure “the right vehicle is on the right road at the right time with the right axel loads and driven at the right s

Identification of sentinel lymph node macrometastasis in breast cancer by deep learning based on clinicopathological characteristics

The axillary lymph node status remains an important prognostic factor in breast cancer, and nodal staging using sentinel lymph node biopsy (SLNB) is routine. Randomized clinical trials provide evidence supporting de-escalation of axillary surgery and omission of SLNB in patients at low risk. However, identifying sentinel lymph node macrometastases (macro-SLNMs) is crucial for planning treatment ta

Elucidating fungal decomposition of organic matter at sub-micrometer spatial scales using optical photothermal infrared (O-PTIR) microspectroscopy

In microbiological studies, a common goal is to link environmental factors to microbial activities. Both environmental factors and microbial activities are typically derived from bulk samples. It is becoming increasingly clear that such bulk environmental parameters poorly represent the microscale environments microorganisms experience. Using infrared (IR) microspectroscopy, the spatial distributi

Microsoft Word - Avhandling - Sara - pdf 040505.doc

Microsoft Word - Avhandling - Sara - pdf 040505.doc TRANSCRIPTIONAL ANALYSIS OF MANTLE CELL LYMPHOMA A GLOBAL SEARCH FOR CELLULAR ORIGIN AND THERAPEUTIC TARGETS Sara Ek Department of Immunotechnology Lund University, Sweden 2004 Akademisk avhandling för avläggande av teknologie doktorsexamen vid Tekniska fakulteten vid Lunds universitet. Avhandlingen kommer att offentligen försvaras på Astronomisk

https://www.immun.lth.se/fileadmin/immun/Avhandlingar/Sara_Ek.pdf - 2026-04-23

Sacos styrelse

Sacos styrelse | Sveriges akademikers centralorganisation Hoppa till huvudinnehåll till startsida Öppna sökruta Öppna Huvudmeny Sök på saco.se Om Saco Kontakt Anställda hos Saco Saco studentråd Sacos styrelse Sacos revisorer Sacos organisation Sacos styrelse Kontaktuppgifter Sacos styrelse Verksamhetsberättelse och årsredovisning Federationen och förbunden Medlemsstatistik Förbunden Saco Hälso- oc

https://www.saco.se/om-saco/kontakt/sacos-styrelse/ - 2026-04-23