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The Primacy of the "We"?

The question of the relation between the collective and the individual has had a long but patchy history within both philosophy and psychology. In this chapter we consider some arguments that could be adopted for the primacy of the we, and examine their conceptual and empirical implications. We argue that the we needs to be seen as a developing and dynamic identity, not as something that exists fu

Plasminogen is a critical host pathogenicity factor for group A streptococcal infection

Group A streptococci, a common human pathogen, secrete streptokinase, which activates the host's blood clot-dissolving protein, plasminogen. Streptokinase is highly specific for human plasminogen, exhibiting little or no activity against other mammalian species, including mouse. Here, a transgene expressing human plasminogen markedly increased mortality in mice infected with streptococci, and this

Learned response sequences in cerebellar Purkinje cells

Associative learning in the cerebellum has previously focused on single movements. In eyeblink conditioning, for instance, a subject learns to blink at the right time in response to a conditional stimulus (CS), such as a tone that is repeatedly followed by an unconditional corneal stimulus (US). During conditioning, the CS and US are transmitted by mossy/parallel fibers and climbing fibers to cere

Building Green in Jordan? Performance Evaluation of the aqaba Residential Energy Efficiency Pilot Project (AREE)

The AREE house was built in 2007/2008 to provide a showcase of a high performance building in Aqaba city in the southern part of Jordan. The total energy performance of the building was achieved through three types of measures grouped into passive design elements, material choices and renewable energy installations. The energy performance and associated costs and benefits for each type were modell

Nuclear mechanisms in cell death induced by HAMLET (human alpha-lactalbumin made lethal to tumour cells)

Popular Abstract in Swedish Celler är de minsta levande beståndsdelarna i kroppens vävnader. Under fosterutecklingen och kontinuerligt under livet behöver vävnaderna storlek regleras och gamla celler bytas ut mot nya. Nya celler bildas genom att de gamla delar sig och celler som är skadade, gamla eller inte längre behövs i vävnaden tas bort genom programmerad celldöd. Det innebär att cellerna brytHAMLET (human alpha-lactalbumin made lethal to tumour cells), a protein-lipid complex originally isolated from human milk, induces programmed cell death selectively in tumour cells. It consists of partially unfolded alpha-lactalbumin in complex with oleic acid. It was previously not known if the unfolding of alpha-lactalbumin alone accounts for the activity of HAMLET or if the lipid adds biologica

Engagemang i Lutherhjälpen : studier av motiv och drivkrafter hos frivilligt aktiva

Popular Abstract in Swedish Del 1. Introduktion I kapitel 1 presenteras arbetets problem, syfte och metod. Det arbete som olika frivilligorganisationer och deras medlemmar utför har de senaste åren uppmärksammats alltmer. Detta ökade intresse finner man såväl i Sverige som internationellt. Fokus i detta arbete riktas mot drivkrafterna bakom frivilligt engagemang. Det övergripande problemet är varfThis thesis focuses on the incitement to commitment and voluntary work. The overall problem is the question why you get involved in voluntary work for an organisation like Lutherhjälpen, the organisation for international development co-operation of the Church of Sweden, one of the largest NGOs of the country. The theoretical perspectives are seen from the position of the increasing pace of change

Protein folding variants, for better or for worse? The lesson learned from HAMLET.

Popular Abstract in Swedish Vad är det för något i human mjölk som dödar cancer celler? Kan “fel” veckade proteiner vara nyttiga? Kan fett vara inblandat i protein veckning? Det är några av frågorna som tas upp i denna avhandling. Allt levande består av proteiner som i sin tur är uppbyggda av amino syror. Det finns 20 st. olika amino syror som på olika sätt kan länkas samman till proteinkedjor. DBy varying its secondary or tertiary structure a single protein can attain new biological functions. The amyloid forming proteins are the best known examples where a change in conformation leads to the formation of amyloid fibrils that accumulate in tissues and cause disease. a-lactalbumin in contrast, is an example of a protein that acquires a beneficial function when the conformation is altered

SGX-Bundler: speeding up enclave transitions for IO-intensive applications

Process-based confidential computing enclaves such as Intel SGX can be used to protect the confidentiality and integrity of workloads, without the overhead of virtualisation. However, they introduce a notable performance overhead, especially when it comes to transitions in and out of the enclave context. Such overhead makes the use of enclaves impractical for running IO-intensive applications, suc

Reading achievement : Its relation to home literacy, self-regulation, academic self-concept, and goal orientation in children and adolescents

Popular Abstract in Swedish Doktorsavhandling undersöker hur förutsättningar i hemmet, självreglering, akademisk självbild och målorientering påverkar läsförmåga. Att kunna läsa bra är grundläggande för att kunna fungera väl i det moderna samhället där man måste kunna läsa komplicerade texter. Då larmrapporter, kring hur många ungdomar som slutar skolan utan att kunna läsa och skriva, regelbundet The studies in this doctoral thesis investigated how home literacy, self regulation, academic self-concept, and goal orientation influence reading ability. Study 1 investigated the effect of family-based prerequisites, reading attitude, and self-regulated learning on reading ability. Students (n= 4,018) in the eighth grade answered the IEA reading literacy test and the SRLQ. Structural Equation Mo

Hydration gradients drive lipid self-segregation

Evaporation from a multicomponent aqueous mixture not only establishes a hydration gradient but may also lead to composition gradients in the other components. Here, we show that such a gradient induces a strong segregation between two phospholipids that differ only in the saturation of their acyl chains. Using high-resolution confocal Raman microscopy combined with small- and wide-angle X-ray sca