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The anti-angiogenic peptide anginex greatly enhances Galectin-1 binding affinity for glycoproteins

Angiogenesis is a key event in cancer progression and therefore a promising target in cancer treatment. Galectin-1, a β-galactoside binding lectin, is up-regulated in the endothelium of tumors of different origin and has been shown to be the target for anginex, a powerful anti-angiogenic peptide with anti-tumor activity. Here we show that when bound to anginex, galectin-1 binds various glycoprotei

Conditions for Reconciliation: Narratives of Survivors from the War in Bosnia and Herzegovina

Abstract in Uncoded languages Namen prispevka:Namen prispevka je analizirati ponovno podane izkušnje 27-ih preživelih vojne v Bosni in Hercegovini v 90-ih letih prejšnjega stoletja. V pripovedih smo pregledali verbalne znake sprave in pomiritve ter analizirali opisane izraze za spravo. Metode: Gradivo za raziskavo je bilo zbrano s kvalitativnimi intervjuji 27-ih posameznikov, ki so preživeli vojnoPurpose: The aim of this article was to analyze the retold experiences of 27 survivors from the 1990s war in Bosnia and Herzegovina. I have examined verbal markers of reconciliation and implacability and analyzed the described terms for reconciliation that are being actualized in the narratives. Design: The material for the study was gathered through qualitative interviews with 27 individuals who

Clinicopathological concordance in dementia diagnostics.

OBJECTIVE: Accurate distinction between dementia subtypes is important for patient care and pharmacological treatment. Continuing systematic comparisons of clinical and neuropathological dementia diagnoses may provide a basis for further improvement of the diagnostic procedure. The purpose of this study was to investigate concordance between clinical dementia diagnosis and neuropathological findin

Analysis of the vascular sounds of the arteriovenous fistula's anastomosis

In this paper, the vascular sounds of the arteriovenous fistula at the anastomosis and five centimeters downstream the anastomosis were analyzed. The analysis of the sounds was based on features extracted from the power spectral density (PSD) and wavelet decomposition. The database consists of 15 recordings at the anastomosis and 15 reference recordings obtained from 15 patients. The results showe

Evaluation of the Sialidase Inhibitor Oseltamivir in GNE-associated Thrombocytopenia

Background: GNE encodes UDP-N-acetyl-glucosamine-2-epimerase/N-acetylmannosamine kinase, the rate limiting enzyme of sialic acid biosynthesis. Biallelic variants in GNE have recently been associated with severe isolated macrothrombocytopenia, attributed to an increased clearance of desialylated platelets. Interestingly, treatment with the sialidase inhibitor oseltamivir has been reported to increa

Robust Decision Analysis under Severe Uncertainty and Ambiguous Tradeoffs : An Invasive Species Case Study

Bayesian decision analysis is a useful method for risk management decisions, but is limited in its ability to consider severe uncertainty in knowledge, and value ambiguity in management objectives. We study the use of robust Bayesian decision analysis to handle problems where one or both of these issues arise. The robust Bayesian approach models severe uncertainty through bounds on probability dis

Are My Employees Able to and Do They Want to Work? : The Baseline Investigation in a Follow up Study Regarding Managers’ Attitudes and Measures to Increase Employees’ Employability in an Extended Working Life

Background: The demographic change affects the retirement age, which has been postponed in many countries. Therefore, the number of senior employees is increasing in the world. However, managers’ attitudes towards their employees’ employability affect the employees’ possibilities regarding whether they can and want to work. Objective: The aim of this study was to evaluate managers’ attitudes towar

Management, Measures and Maintenance: : Success and Setbacks in Interventions Promoting a Healthy and Sustainable Employability and Working Life for All Ages

Background: The labour force is ageing due to the demographic change and the postponement of old-age retirement in many countries. Objective: In order to increase the possibility for employees to maintain their employability and to keep working in an extended working life this intervention project tested a distance education as a technique to integrate a theoretical model for a sustainable working

Ngnat programplan

Utbildningsplan Naturvetenskapligt kandidatprogram Naturvetenskapliga fakulteten NGNAT, Naturvetenskapligt kandidatprogram, 180 högskolepoäng Sciences, 180 credits Program utan akademiska förkunskapskrav och med slutlig examen på grundnivå / First cycle degree programme not requiring previous university study Beslutsuppgifter Utbildningsplanen är fastställd av Naturvetenskapliga fakultetsstyrelsen

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/ngnat_programplan.pdf - 2026-05-19

The Satanic Panic of the Warrens – ”The Conjuring: The Devil Made Me Do It” and the Satanic Cult Horror Film

This thesis examines the Satanic cult in horror film – historically and in contemporary horror films. A quantitative analysis of horror films with themes of Satanism and Satanic cults is presented, in which three particular upswings in the themes are seen – one in the 1970s, one in the late 1980s and early 1990s, as well as one from the mid 2010s and onwards. In the thesis’ second part, The Conjur

Att bli trampad på i mötet med psykiatrin: Förekomst och uttryck av kränkningar inom den vuxenpsykiatriska vården

Tidigare forskning har visat att patienter inom vuxenpsykiatrisk vård utsätts för kränkningar av vårdpersonal, där dehumanisering och stigmatisering av psykisk sjukdom ses som bidragande faktorer. Denna studie ämnade undersöka om det fanns skillnader mellan anmälningar till Inspektionen för vård och omsorg (IVO) rörande kränkande bemötande jämfört med anmälningar rörande andra bemötandebrister, utPrevious research has shown that patients in adult psychiatric care are subject to abuse by healthcare staff, where dehumanization and stigmatization of mental illness are seen as contributing factors. This study aimed to investigate whether there were differences between reports to the Health and Social Care Inspectorate (IVO) concerning abusive treatment compared to reports concerning other trea

Institutional Investors and Sustainability - An Analysis of Institutional Investors’ Legal Due Diligence Obligations

The European Union’s Sustainable Finance Agenda has launched several new actions in order to reorient capital flow of the financial market to sustainability objectives. One of these initiatives was to unify and harmonize the rules on marketing of sustainable aims of financial products. Financial Market Participant, including institutional investors, are obligated to disclose their due diligence po

The Making of a Philosopher : The Contemplative Letters of Charles de Bovelles

Today the importance of epistolary networks for intellectuals in early modern Europe is well appreciated. Nevertheless, connections reaching outside the canon of celebrated humanists and scientists in the Republic of Letters are little studied. This article examines how Charles de Bovelles (1479-1567) used letters to establish a philosophical persona and publicize his contemplative approach to nat