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Selected issues of law and ergonomics in maritime security

The paper examines in selected detail, issues of maritime security in international law that are currently at the forefront of concerns in the maritime world. It provides an overview of the nature of maritime security contra maritime safety and gives an introduction of the most common threats. It looks at the current scenario in light of what is evolving in response to certain dramatic events of t

Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene.

The Ncf1 gene was recently identified as a strong regulator of severe arthritis in rat. This finding was surprising, because the disease-promoting allele mediated a lower level of reactive oxygen species in NADPH oxidase-expressing cells. We have now investigated a splice mutation of the Ncf1 gene in B10.Q mice, causing a truncated and nonfunctional Ncf1 protein. We found that the mutated Ncf1 led

The Molecular Motor F-ATP Synthase Is Targeted by the Tumoricidal Protein HAMLET.

HAMLET (human alpha-lactalbumin made lethal to tumor cells) interacts with multiple tumor cell compartments, affecting cell morphology, metabolism, proteasome function, chromatin structure and viability. This study investigated if these diverse effects of HAMLET might be caused, in part, by a direct effect on the ATP synthase and a resulting reduction in cellular ATP levels. A dose-dependent reduc

Ligand induced galectin-3 self-association.

Many functions of galectin-3 entail binding of its carbohydrate recognition site to glycans of a glycoprotein, resulting in cross-linking thought to be mediated by its N-terminal non-carbohydrate-binding domain. Here we studied interaction of galectin-3 with the model glycoprotein asialofetuin (ASF), using a fluorescence anisotropy (FA) assay to measure the concentration of free galectin carbohydr

Swedish health care providers' experience and knowledge of female genital cutting.

We sought to evaluate the experiences and knowledge of health care providers in Sweden regarding female genital cutting (FGC) as a health issue. Questionnaires (n = 2,707) were sent to providers in four major cities in Sweden and evaluated by means of descriptive statistics. Twenty-eight percent (n = 769/2,707) responded, of whom 60% had seen such patients. Seven providers, including 2 pediatricia

Low Resolution Solution Structure of HAMLET and the Importance of Its Alpha-Domains in Tumoricidal Activity.

HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is the first member in a new family of protein-lipid complexes with broad tumoricidal activity. Elucidating the molecular structure and the domains crucial for HAMLET formation is fundamental for understanding its tumoricidal function. Here we present the low-resolution solution structure of the complex of oleic acid bound HAMLET, derived

Den huvudlösa idén : Medborgarlön, välfärdspolitik och en blockerad debatt

Popular Abstract in Swedish Medborgarlön - ett statligt bidrag som ges till alla medborgare utan inkomst- eller behovsprövning - har varit flitigt diskuterat inom akademiska kretsar under senare år. Bland argumenten för medborgarlön återfinns att det antas ge ett erkännande åt obetalt arbete inom hemmet, en mer jämlik fördelning av lönearbete genom att uppmuntra deltidsarbete, leda till minskad ofBasic income - an income granted by the government to each full member of society without means tests or work requirements - has been a widely discussed subject among academics in recent years. However, basic income has not, in most cases, reached the formal political agenda. The main aim of this book is to discuss why this is the case, with Sweden as the focus of the discussion. The aim is also t

Galectin-4 in normal tissues and cancer

Galectin-4 belongs to a subfamily of galectins composed of two carbohydrate recognition domains within the same peptide chain. The two domains have all the conserved galectin signature amino acids, but their overall sequences are only approximately 40% identical. Both domains bind lactose with a similar affinity as other galectins, but their respective preferences for other disaccharides, and larg

A short delay from out of hospital cardiac arrest to call for ambulance increases survival

Aim To describe the relative impact on survival of the delay from estimated time of collapse to call for an ambulance among patients who suffer from a bystander witnessed out of hospital cardiac arrest of a cardiac aetiology. Methods A majority of all ambulance organizations in Sweden (covering 85% of Sweden inhabitants) participate in a National survey of out of hospital cardiac arrest. Results I