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The present study aims to describe accelerometer-assessed physical activity (PA) patterns and fulfillment of PA recommendations in a large sample of middle-aged men and women, and to study differences between subgroups of socio-demographic, socio-economic, and lifestyle-related variables. A total of 27 890 (92.5% of total participants, 52% women, aged 50–64 years) middle-aged men and women with at

Russ et al. show that human astrocytes adopt different reactive immune phenotypes when exposed to either TNF-α or alpha-synuclein fibrils, which are exogenous stressors that compete to drive the astrocyte immune reactive response. They also show that PARK2-variant-containing astrocytes exhibit an exacerbated response to the stressors, accompanied by bioenergetic defects.

This study presents how sequential infiltration synthesis of trimethyl aluminium and water into a carbohydrate-based block copolymer was used to enable pattern transfer of 6 nm half-pitch horizontal cylinders into silicon. Specular neutron reflectometry measurements of poly(styrene)-block-maltoheptaose self-assembled into horizontal cylinders indicate an increasing content of alumina after each se

The Witch of Edmonton has frequently been read as a play which exposes the social problems that led to witchcraft accusations in early modern society. This article examines another aspect of the play which has not yet been adequately discussed by literary scholars: the role of physiology, and especially the role of human blood, in the play’s representation of witchcraft and the devil’s manipulatio

Background Indications with poor T-cell infiltration or deficiencies in T-cell priming and associated unresponsiveness to established immunotherapies represent an unmet medical need in oncology. CD40-targeting therapies designed to enhance antigen presentation, generate new tumor-specific T cells, and activate tumor-infiltrating myeloid cells to remodel the tumor microenvironment, represent a prom

A respiratory virus emitted in an aerosol particle will experience a tough journey with many obstacles before finding a new host where it can cause an infection (Fig. 1). By every second, its chances to replicate decrease due to removal by building ventilation, deposition on surfaces, or loss in infectivity. Thus, the transport of infectious viruses from the exhaled breath of one person to the inh

Abstract in UndeterminedThe aim of this study was to investigate how well subjects beat out a rhythm using eye movements and to establish the most accurate method of doing this. Eighteen subjects participated in an experiment were five different methods were evaluated and a fixation based method was found to be the most accurate. All subjects were able to synchronize their eye movements with a giv

Forestry has been one of the major industries in the Swedish economy since the middle of the nineteenth century. During the second part of the twentieth century the industry went through powerful technological changes. Traditional handicraft methods were replaced by modern high technology. As for the forestry VET this meant a strong expansion during the 1950s and 1960s followed by integration into

Barbiturates enhance the binding of [3H]diazepam to benzodiazepine receptor sites in rat brain. This effect occurs at pharmacologically relevant concentrations of barbiturates, and the relative activity of a series of compounds correlates highly with anesthetic activity of the barbiturates and with their ability to enhance postsynaptic inhibitory responses to the neurotransmitter γ-aminobutyric ac

The aim of the present study was to determine the pollution load originating from storm water on Lake Vaxjosjon. Each year about 1,050,000 m3 of storm water are discharged into the lake. Storm water represents a substantial pollution source for the lake and therefore also a main reason for the hypertrophic conditions in the lake. In order to evaluate the effects of the discharged storm water on th

The use of protective gloves is of importance in workplaces where hazardous chemicals are handled, including the chemical industry, the plastic industry, as well as in environments such as dental practices, hairdressing, and beauty salons. Occupational dermatology can provide crucial advice regarding how to avoid or protect the patient against allergens found in the work environment and provide th