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Characterization of the P13 membrane protein of Borrelia burgdorferi by mass spectrometry

Borrelia burgdorferi sensu lato is a tick-borne pathogen that causes Lyme disease. The characterization of membrane proteins from this and other pathogens may yield a better understanding of the mechanisms of infection and information useful for vaccine design. Characterization of the highly hydrophobic Borrelia outer membrane component P13 from a mutant (OspA- OspB- OspC- and OspD-) strain was un

Democratic Tourism

The introduction of paid holidays during the interwar years democratized travel and laid the foundation for modern mass tourism. In European democracies, the right to paid leave found supporters from across the political spectrum who viewed it a means to improve the health of the labor force, increase industrial output, and safeguard family values. Workers also gained new leisure opportunities in

World War II at 24 Frames a Second : Scandinavian Examples

Historia förmedlas ofta på ett inflytelserikt sätt på film. I "World War II at 24 Frames a Second" jämförs filmiska representationer av andra världskriget i Danmark, Norge och Sverige med fokus på den senaste tioårsperioden.

Offerkast and Roadside Memorials

The erection of roadside memorials in Sweden is commonly considered a novel practice, appearing during the last 10-15 years. Nevertheless similar precedent practices can be found in the history of Sweden. Stories about marking the site of an unexpected death with a cross could be said to date back to the eleventh century legend of Saint Sigfrid, telling of the first English missionary to spread C

Chromosomal Instability and Genomic Amplification in Bone and Soft Tissue Tumours

Popular Abstract in Swedish De flesta cancerformer uppvisar förvärvade kromosomavvikelser. En del enklare avvikelser har visat sig förekomma enbart i en viss tumörform och kan därför användas som diagnostiska markörer. I de flesta fall föreligger emellertid ett komplext och ospecifikt avvikelsemönster, ibland med ett mycket kraftigt ökat antal kopior av vissa DNA-sekvenser, så kallad genamplifieriAcquired genetic abnormalities are found in all types of malignant tumours and may contribute to neoplastic processes by altering protein structure or dosage. Many bone and soft tissue tumours (BSTT) are characterised by complex patterns of chromosome changes, including extensive intratumour heterogeneity and amplification of DNA sequences. The results presented in this thesis demonstrate that the