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Elucidating regulators of red blood cell development in health and disease

Våra röda blodkroppar lever i genomsnitt 120 dagar och bryts därefter ner avmakrofagerna, immunsystemets medfödda städare av både främmande och egnaceller. De röda blodkropparnas uppgift är att transportera syre från lungorna tillkroppens olika vävnader och föra tillbaka koldioxid. Men vad händer om de rödablodkropparna bryts ner ovanligt snabbt eller helt enkelt inte produceras i tillräckligtsnabRed blood cells are are plentiful, flexible and essential. They are the most abundant cell in our body and their mainobject is to carry oxygen, which is essential for cellular respiration. The formation of red blood cells is callederythropoiesis. Erythropoiesis is intimately coupled to cell division and mitochondrial function. Aberrations in thesetwo processes are often associated with red blood c

Monitoring the standard – here, now and in person : Detecting accessibility faults as an engaged citizen

This chapter analyses volunteer work for identifying and reporting accessibility faults in urban settings. By looking closely at how people monitor adherence to the accessibility standards of laws and human rights, it is possible to recognise and understand their concrete fight against exclusion and discrimination. The author uses ethnographic data from go-alongs with two ‘accessibility detectives

Social Media Sad Girls and the Normalization of Sad States of Being

This paper examines virtual manifestations of “sad girls” on the media platform Tumblr. Here users write about their struggles with mental illness, revealing a set of shared experiences that encompass both psyche and body. Predominant narratives of what it means to be mentally ill are questioned, and alternative conceptualizations of the psyche are introduced. I argue that the sad girls legitimize

Live well, die well - an international cohort study on experiences, concerns and preferences of patients in the last phase of life: the research protocol of the iLIVE study

Introduction Adequately addressing the needs of patients at the end of life and their relatives is pivotal in preventing unnecessary suffering and optimising their quality of life. The purpose of the iLIVE study is to contribute to high-quality personalised care at the end of life in different countries and cultures, by investigating the experiences, concerns, preferences and use of care of termin

Daedalus flykt

The Swedish inventor and scientist Christopher Polhem (1661-1751) has been called the Daedalus of the North. This article concerns the picture of Polhem through the ages, what has been written concerning him, and about the still surprisingly modest research on him. First gives a short introduction to Polhem. His own life story, put forward by himself, has had an immense influence on the following

A mean field theory learning algorithm for neural networks

Based on t he Boltzmann Machine concept, we derive alear ning algorithm in which time-consuming stochastic measurementsof correlations a re replaced by solutions to dete rminist ic mean fieldtheory equ ations. T he method is applied to t he XOR (exclusive-or ),encoder, and line sym metry problems with substantial success. Weobserve speedup facto rs ranging from 10 to 30 for these ap plicat ionsand

The Later Life Audio and Radio Co-operative: considering radio as a technology to promote citizen dialogue in later life

The Later Life Audio and Radio Co-operative (LLARC) is an England-widenetwork of older content creators, age-inclusive radio stations,third sector organisations, local authorities and academics workingon ageing issues. The co-operative was established in 2019 as anoutcome from a participatory action research project. Aiming topromote talk-based content created by older adults, the LLARCadvocates f

Gender by design : Performativity and Consumer Packaging

Mass-produced consumer packages are everyday objects that almost go unnoticed. However, by claiming things such as the essence of femininity or masculinity, they affect us and are co-creators of our reality. Based on visual ethnography, this article traces the representation of gender on mass-produced packaging during a time when male privilege is being challenged and female visual objectification

Breast cancer diagnosis using extended-wavelength diffuse reflectance spectroscopy : comparing tumor subgroups

Optical imaging utilize light to analyze biological tissues in detail, non-invasively and without harmful radiation. Examples include ultrasound optical tomography and photoacoustic imaging; both use a limited number of wavelengths. Diffuse reflectance spectroscopy, another optical technique, covers a continuous wavelength range, but without generating an image. This study focuses on extended-wave

Förändrade förutsättningar för samverkan : Idéburna erfarenheter av idéburen offentlig samverkan med utgångspunkt i NAD

Rapporten presenterar resultaten av en studie som vi genomfört på uppdrag av Nätverket Idéburen Sektor Skåne och handlar om idéburna erfarenheter av samverkan med offentliga organisationer inom NAD. Syftet är att förstå hur strukturella förändringar och organisatoriska strategier har påverkat samverkan över tid. Tidsperioden sträcker sig från 2016 då vi genomförde en utvärdering av samverkan och 2