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The role of CysLT1R in animal models of colorectal cancer

Popular Abstract in Swedish Det finns ett starkt samband mellan kronisk inflammation och cancer. Ett av de mer etablerade sambanden är den mellan kronisk inflammation i tarmen och den i Sverige tredje vanligaste cancersjukdomen, nämligen tjocktarmscancer. Risken för tjocktarmscancer korrelerar med inflammationsutbredning, varaktighet och svårighetsgrad. Den inflammatoriska processen regleras av reCysteinyl leukotrienes (LTC4, LTD4 and LTE4) are potent pro-inflammatory lipids derived from arachidonic acid and mediate their effect through CysLT1R and CysLT2R. There is a strong correlation between long-standing inflammatory bowel disease where these pro-inflammatory mediators are abundant and colorectal cancer. We have shown that LTD4 via its receptor CysLT1 induces expression of proteins ass

Genetic and Metabolic Markers for the Development of Diabetes after Gestational Diabetes Mellitus

Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING PÅ SVENSKA Graviditetsdiabetes (GDM) definieras som ett diabetestillstånd som upptäcks under graviditet. Ofta orsakas detta tillstånd av de hormonförändringar som uppträder under graviditet vilka medför en ökad insulinresistens, dvs. ett ökat motstånd mot insulinets effekter. Diagnosen GDM utesluter dock inte diabetes av annan orsak soThe aims of this work were to determine the prevalence of postpartum diabetes among women with gestational diabetes mellitus (GDM) in a prospective study 5 years postpartum; to characterize these women according to insulin secretion, insulin sensitivity, autoimmunity and genetics; and to identify possible markers and predictors for the development of manifest diabetes. The subjects were recruited

Emerging aspects of nanotoxicology in health and disease: From agriculture and food sector to cancer therapeutics.

Nanotechnology is an evolving scientific field that has allowed the manufacturing of materials with novel physicochemical and biological properties, offering a wide spectrum of potential applications. Properties of nanoparticles that contribute to their usefulness include their markedly increased surface area in relation to mass, surface reactivity and insolubility, ability to agglomerate or chang

Kulturlandskapets förändringar inom röjningsröseområdet Yttra Berg, Halland : en pollenanalytisk undersökning av de senaste 5000 åren

Populärvetenskaplig sammanfattning: Röjningsrösen kan härstamma från bronsålder och ända in i modern tid. De är svåra att datera då det inte finns några karaktäristika för ett röse som skapats under en viss tidsepok. Röjningsröseområden är likväl en stor källa till kunskap om hur jorden brukats under förhistorisk och historisk tid. Med hjälp av paleoekologi kan den förhistoriska miljön studeras. PIn the village Berg, Gällared’s parish, Halland, there is an area with 60 to 75 hectares of abandoned arable fields is present. Within Berg, Yttra Berg’s nature reserve is situated, where 9 hectares of the abandoned arable fields has been recorded, consisting of clearance cairns, terraces and stone walls. Close to the recorded abandoned arable fields a smaller bog, Sänkemosse, is situated. Nearby

Beslutsunderlag för kommunens handlingsprogram -– med fokus mot förebyggande av vardagsolyckor

Based on a new Swedish legislation for accident prevention and protection the support of the establishment of municipality accident prevention programs with documented basic data sets for decision-making is discussed. A division into four documents of basic data sets is proposed. A process is projected for the production, decree and compliment of municipal accident prevention programmes and the do

Testing for Periodicity and Trend in Long-Memory Processes

Popular Abstract in Swedish Avhandlingen handlar om tes av periodicitet och trend inom långminne-processer. Med hjälp av diskret wavelet transform och periodogram presenteras vi två test för periodicitet och tre test för trend. Vi utvärderar vår test samt studerar deras egenskaper delvis genom att använda oss av datorintensiva metoder såsom Monte Carlo och delvis genom att jämföra dem med andra liThis thesis presents methods of testing the periodicity and trend for the time series, which exhibit dependence over long periods of time. Many such processes can be modeled by a class of models called fractionally differenced processes. The first approach we consider to analyse such processes is by using the band periodogram, which divides the periodogram into different intervals or bands, matchi

The Children’s Revised Impact of Event Scale (CRIES): Validity as a screening instrument for PTSD.

The Children’s Revised Impact of Event Scale (CRIES) is a brief child-friendly measure designed to screen children at risk for Posttraumatic Stress Disorder (PTSD). It has good face and construct validity, a stable factor structure, correlates well with other indices of distress, and has been used to screen very large samples of at-risk-children following a wide range of traumatic events. However,

Mechanosensing in the vascular wall - the role of cellular microdomains in vascular remodeling

Popular Abstract in Swedish I denna avhandlig undersöks hur mekanisk sträckning påverkar den glatta muskulaturen som omger våra blodkärl. En ökad sträckning av blodkärlen sker till exempel vid högt blodtryck vilket leder till en förändrad struktur av kärlet, så kallad remodellering. Ett annat mekaniskt stimuli utgörs av blodets friktion mot de endotelceller som täcker blodkärlens kontaktyta mot blThe vascular wall has a remarkable capacity to adapt to mechanical forces exerted by the intraluminal blood pressure and flow. This includes rapid change in contractile tone as well as chronic alteration of vessel structure if the stimulus persists. Stretch of the intact blood vessel wall promotes growth and contractile differentiation. The molecular mechanisms involved are not well defined, but c

Essays on Sickness Insurance, Absence Certification and Social Norms

Popular Abstract in Swedish Avhandlingen består av ett inledande kapitel och tre essäer, som studerar sjukpenningförsäkringen, sociala normer och sjukskrivning. Den första essän, Group-Specific Social Norms and Economic Incentives in a General Welfare System, behandlar interaktionen mellan ekonomiska och sociala drivkrafter i ett generellt bidragssystem. Vi anknyter resultaten till sjukpenningförThe thesis consists of an introductory chapter and three essays, considering sickness insurance, social norms and absence certification. The first essay, Group-Specific Social Norms and Economic Incentives in a General Welfare System, investigates the interaction between economic incentives and social influences in a general welfare system. We relate the results to sickness insurance. The model i

Correspondence between areas causing recall in breast cancer screening and artificial intelligence findings

False positive recall is a major issue in breast cancer screening and the introduction of artificial intelligence (AI) might affect which women who are unnecessarily recalled. We have investigated how an AI system works on false positive recalls at screening and compared with radiologist findings. Two-view digital mammography (DM) examinations from 656 recalled women (136 with screening detected c

Particle-physics-cosmology

Microsoft Word - PARTICLE PHYSICS.docx 1 PARTICLE PHYSICS AND COSMOLOGY Lars Gislén Hans-Uno Bengtsson Gösta Gustafson Department of Theoretical Physics, Lund University Spring 2001 2 3 Chapter l. Quarks, leptons and forces The fundamental particles of matter are quarks and leptons. They can be arranged in three families or generations according to the following scheme: Electric charge u d ⎛ ⎝⎜ ⎞

https://www.particle-nuclear.lu.se/sites/particle-nuclear.lu.se/files/2025-01/particle-physics-cosmology.pdf - 2026-05-20

Strategi- och kvalitetsdokument 2018

1 STRATEGI- OCH KVALITETSDOKUMENT Strategi- och kvalitetsdokument INSTITUTIONEN FÖR PSYKOLOGI | 2018 Vision En Institution som genom forskning och utbildning inom den psykologiska disciplinen förstår, förklarar och för- bättrar vår värld och människors villkor i samverkan med omvärlden och det samhälle vi lever och verkar i. 3 STRATEGI- OCH KVALITETSDOKUMENT Forskning FORSKNINGSMÅL Institutionen f

https://www.psy.lu.se/sites/psy.lu.se/files/strategi-_och_kvalitetsdokument_2018.pdf - 2026-05-20

LPED 2019 7

Centre for Economic Demography Lund University School of Economics and Management P.O. Box 7083 SE-220 07 Lund, Sweden www.ed.lu/publications/Lund-Papers-in-Economic-Demography/ Reconstruction of Regional and National Population Using Intermittent Census-Type Data: The Case of Portugal 1527-1864 NUNO PALMA, JAIME REIS, MENGTIAN ZHANG LUND PAPERS IN ECONOMIC DEMOGRAPHY 2019:7 Copyright is held by t

https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-07/LPED_2019_7.pdf - 2026-05-20

Sv M03 LA03 Linser och Teleskop

M03 Lärarhandledning: Linse och teleskop Lärarhandledning för ”Linser och Teleskop” | sida 1 av 6 Lärarhandledning Modul 3 Linser och Teleskop Linser är en optisk grundkomponent. Att förstå hur linser fungerar är inte alltid trivialt! Linsers har en stor variation på användningsområden. Ett av användningsområdena är teleskop, som gör det möjlighet att titta på himlakroppar. I den här modulen komme

https://www.nrcf.lu.se/sites/nrcf.lu.se/files/2025-05/sv_M03_LA03_Linser_och_Teleskop.pdf - 2026-05-20

Publication In Development

© 2022. Published by The Company of Biologists Ltd. Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain Marcella Birtele 1 , Petter Storm 1 , Yogita Sharma 1 , Janko Kajtez 1 , Jenny Nelander Wahlestedt 1 , Edoardo Sozzi 1 , Fredrik Nilsson 1 , Simon Stott 3 , Xiaoling L He 3 , Bengt Mattsson 1 , Daniella Rylander

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/2022-12/publication%20in%20development.pdf - 2026-05-20

Att skriva en renässans: The New Negro och vägen till en ny svart nationalism 1917–1925

Writing a Renaissance: The New Negro and the path to a new Black nationalism 1917–1925 The New Negro: an Interpretation (1925), edited by the philosopher and critic Alain Locke, is regarded as a central text concerning the literary movement known as the Harlem Renaissance. Widely viewed as documenting the transition of Black American litterature into the age of modernism. The anthology sought to

Distributed fibre-Optic Acoustic sensing : a tool to assess rock properties during active and passive seismic surveys

Ubiquitously used for monitoring pipelines and infrastructures, distributed fibre-optic acoustic sensing is becoming an emerging technology for earthquake monitoring thanks to the possibility to interrogate a large vast of distances with a dense number of sensing points in which an optical fiber cable can be retrofitted. Moreover, it can also be used as a tool by geophysicists for the characteriza

Iron Cages; Liquid Scholars: : Exploring the valuable coordination of higher education scholarships in the international knowledge society

Denna avhandling breddar rådande förståelser av stipendier och deras systematiska användning inom internationell högre utbildning genom att introducera en ny uppsättning teoretiska verktyg för att undersöka sådana satsningar. Med fokus på organisationer i Mexiko och Indonesien samt de studenter de sponsrade till svenska masterprogram mellan 2013 och 2020, utforskar studien värderingsprocesser, samThis thesis broadens prevailing understandings of scholarships and their systematic use in international higher education, introducing a novel set of theoretical tools for examining such endeavors. Focusing on organizations in Mexico and Indonesia and the students they sponsored in Swedish master’s degree programs between 2013-20, the study explores valuation processes, coordination puzzles and et

Diagnostic performance and clinical implications of the World Health Organization Reporting System for Lymph Node Cytopathology

Introduction A World Health Organization (WHO) system has recently been introduced to standardize reporting of lymph node fine-needle aspiration biopsy (LN-FNAB) cytopathology. Herein, we analyze its diagnostic performance in a routine setting.Materials and methodsWe reviewed 2274 consecutive lymph node fine-needle aspiration biopsies categorized according to the WHO system. Corresponding histolog

An evaluation of functional size methods and a bespoke estimation method for real-time systems

Functional size, or function points, is a language-independent measure of software size. It is used as an estimator of development effort and software code size, in particular in the domain of information systems, while in real-time systems it is not so widely spread. In this paper, functional size measurements are empirically evaluated by applying them to a recently completed project. Two establi