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Differential gene-expression between large and small-billed subspecies of Tristan Finches, Nesospiza acunhae - investigating imprints of speciation and sex-specific expression

Evolutionsteorin förklarar hur djur och andra organismer förändras över tid. I dess historia beskrivs hur vi alla kommer från samma ursprung, från enkla organismer som uppstod för miljontals år sedan, till den otroliga mångfald och komplexitet som vi ser i naturen idag, inklusive oss människor. Vi människor härstammar allesammans från en aplik förfader som vi delar med schimpanser, och längre till

Power Of The Many - En flerfallsstudie om hur inträdesbarriärer kan övervinnas med hjälp av crowdfunding

Examensarbetets titel: Power of The Many. En flerfallsstudie om hur inträdesbarriärer kan övervinnas med hjälp av crowdfunding Seminariedatum: 2018-01-11 Ämne/kurs: FEKH19, Företagsekonomi, Examensarbete i Strategic Management på kandidatnivå Författare: Axel Karlsson, Jacob Ridderberg och Anton Tholén Handledare: Merle Jacob Nyckelord: Crowdfunding, digitalisering, inträdesbarriärer, startups, et

Characterization of Subscriber Local Loop by Measures and Analysis of Frequency and Impulse Responses

This paper presents methodologies that could be used for characterizing subscriber telephone loops that carry DSL services (ADSL and ADSL2+), by determination and analysis of frequency response, time domain reflectometry, and impulse response of the line. From this analysis, the subscriber loop length, identification and location of impairments such as bridged taps, gauge changes, and open ended t

Local maxima of Gaussian fields

The structure of a stationary Gaussian process near a local maximum with a prescribed heightu has been explored in several papers by the present author, see [5]–[7], which include results for moderateu as well as foru→±∞. In this paper we generalize these results to a homogeneous Gaussian field {ξ(t) t ∈ R n}, with mean zero and the covariance functionr(t). The local structure of a Gaussian field

ICT-enabled refugee integration : A research agenda

The recent phenomenon that has become known as the European refugee crisis is, in reality, a global problem. Accordingly, issues regarding refugee integration have become a central debate topic worldwide. In this paper, we examine how refugees use information and communication technology (ICT) in different regions across the world to understand how ICT supports their desperate journey to safety, t

Factors influencing the efficacy of an online behavioural intervention for children and young people with tics : Process evaluation of a randomised controlled trial

The Online Remote Behavioural Intervention for Tics (ORBIT) trial found that an internet-delivered, therapist-supported, and parent-assisted Exposure and Response Prevention (ERP) intervention reduced tic severity and improved clinical outcomes. This process evaluation aimed to explore mechanisms of impact and factors influencing efficacy. Participants were 112 children with a tic disorder and the

Storsjöodjuret i ett kalejdoskop. Humanekologiska perspektiv på en svensk kryptid.

"Storsjöodjuret”, eller “The Great Lake Monster”, är ett undflyende fenomen i sjön Storsjön, belägen i landskapet Jämtland i norra Sverige. Denna avhandling i ämnet humanekologi undersöker hur det sammankopplingar av det sociala, det kulturella, det historiska och det lokala påverkar formandet av detta svenska kryptid, eller “dolda djur”. Syftet med studien är att visa hur detta vetenskapligt ännuStorsjöodjuret, or The Great Lake Monster, is an elusive phenomenon in lake Storsjön, situated in the province of Jämtland in Northern Sweden. This dissertation in Human Ecology investigates how the intricate web of the social, the cultural, the historical, and the local influence the shaping of this Swedish cryptid, or “hidden animal”. The purpose of the study is to demonstrate how this scientifi

A Neural Network Based Early Warning System for Diarrheal Disease Burden in the Asia Pacific Region

BACKGROUND AND AIM: Warming temperature promotes bacterial growth while extreme precipitation enhances fecal-oral route of exposures to these pathogens, particularly in resource limited settings, increasing burden of diarrheal diseases. Given climate change related increases in frequency of extreme events, there is a pressing need to develop meaningful early warning system with adequate lead time

First-in-human, multicenter, open-label, phase I study of ATOR-1017 (evunzekibart), a 4-1BB antibody, in patients with advanced solid malignancies

BACKGROUND: ATOR-1017 (evunzekibart) is a human agonistic immunoglobulin G4 antibody targeting the costimulatory receptor 4-1BB (CD137). ATOR-1017 activates T cells and natural killer cells in the tumor environment, leading to immune-mediated tumor cell death.METHODS: In this first-in-human, multicenter, phase I study, ATOR-1017 was administered intravenously every 21 days as a monotherapy to pati