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The association between pesticide exposure and non-Hodgkin lymphoma (NHL) including hairy cell leukemia (HCL) was analyzed in a pooled study of three case-control studies. Results on exposure to pesticides were based on 1,425 cases and 2,157 controls participating in the studies. Exposures were assessed by self-administered questionnaires completed as needed by phone. In the pooled univariate anal
We investigate specific anion binding to a range of patchy protein models and use our results to probe protein-protein interactions for aqueous lysozyme solutions. Our molecular simulation studies show that the ion-protein interaction mechanism and strength largely depend on the nature of the interfacial amino acid residues. Via direct ion pairing, small anions interact with charged side-chains wh
A search for new phenomena is presented in final states with two leptons and one or no b-tagged jets. The event selection requires the two leptons to have opposite charge, the same flavor (electrons or muons), and a large invariant mass. The analysis is based on the full run-2 proton-proton collision dataset recorded at a center-of-mass energy of s=13 TeV by the ATLAS experiment at the LHC, corres
CONTEXT: The epidemiological signature of renal cell carcinoma (RCC) during the past decades is explained by overdetection and overtreatment of indolent cancers; furthermore, a non-negligible proportion of patients undergoing surgery for suspected RCC harbour benign renal tumours. As the gold standard for RCC diagnosis remains histopathological analysis of surgical or biopsy specimens, implementat
Cities are messy, planning is messy. Things do not come together as nicely as we would like; they do not necessarily add up. It is one thing to say that cities are multifaceted and complex and quite another to engage with and study this complexity and make sense of it. STS provides a way to interpret and engage with urban messiness without oversimplifying and missing out on the essence of cities.
This paper is centered around using poetic-mythological vocabulary from Northwest Semitic languages as a key to reconstruction of IE phraseology. Mythological material from the NWS area – especially Ugaritic – can sometimes be shown to represent Indo-European borrowings into NWS poetic language; by studying these cases, knowledge may be gleaned about the loan-giver.The famous phrase *egwhent ogwhi
This paper investigates the drivers for, and implementation of, digital transformation projects and organizational change initiatives in 20 companies in the UK. The study follows on previous research based on the Socio-Technical Toolbox [STT], specifically focusing on the activity analysis and employees’ experience and participation in the change initiative or digital transformation project.
We use a novel method to define the R&D team and use the unexpected death of an R&D worker to study its effect on the organization of R&D teams in profit-making firms. Average treatment effects on exit probability, entry probability, wages of stayers, and characteristics of leavers are null. Hires are slightly younger in treatment than control. Treatment effects do not vary by the size
A search for long-lived particles decaying into hadrons is presented. The analysis uses 139 fb−1 of pp collision data collected at s = 13 TeV by the ATLAS detector at the LHC using events that contain multiple energetic jets and a displaced vertex. The search employs dedicated reconstruction techniques that significantly increase the sensitivity to long-lived particles decaying in the ATLAS inner
EU competition policy report
Playing outdoors in nature with peers has been attributed most importance for children's healthy development but is increasingly marginalized because of the attractiveness of screen-based play. Careful merging of digital technology into outdoor play environments rich on nature elements could potentially help bridge digital play with more traditional play activities outdoors. A systematic compariso
I provide a unified account of hope and fear as propositional attitudes. This “mirror account” is based on the historical idea that the only difference between hope and fear is the conative attitude involved, positive for hope and negative for fear. My analysis builds on a qualified version of the standard account of hope. The epistemic condition is formulated in terms of live possibility and the
Climate Change, Disasters and the Refugee Convention is concerned with refugee status determination (RSD) in the context of disasters and climate change. It demonstrates that the legal predicament of people who seek refugee status in this connection has been inconsistently addressed by judicial bodies in leading refugee law jurisdictions, and identifies epistemological as well as doctrinal impedim
Therapy is the often-used treatment for cancer patients, even those that undergo resection surgery. While milestones have been surpassed throughout the decades for a number of cancer types, there are those that comprise of characteristics limiting effectiveness of treatments. For these, such as some breast and pancreatic cancers, other pursuits must be explored to identify avenues for beneficial t
This chapter presents and discuss a platform for small-scale drug candidate production, process development and performance studies of integrated continuous downstream processes. The main idea of the platform methodology is to use common available equipment and reconfigure them for advanced downstream processing. Five different industrial case studies are discussed. The resulting processes are aut
How are bribes supposed to be given or taken? In this article, we study how individuals from countries with low tolerance of corruption learn, teach others and present themselves as knowledgeable about the etiquette of bribes. This involves the social practices of everyday corruption and petty bribes when working as ’strangers’ in countries where such exchanges are more common. Previous interviews
